There are 8 ways to get from Manitowoc to Des Moines by taxi, plane, bus (Greyhound), car, bus, train, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Appleton International Airport, fly
best- Take the taxi from Manitowoc to Appleton International Airport (ATW)taxi
- Fly from Appleton International Airport (ATW) to Des Moines (DSM)plane ATW - DSM
5h$244–859Drive 400.4 mi
cheapest- Drive from Manitowoc to Des Moinescar 400.4 mi
7h 45m$74–106Bus (Greyhound)
- Take the bus from Manitowoc to Chicago Bus Stationbus Greyhound US0150S
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
11h 33m$82–174Bus to Green Bay, fly
- Take the bus from Manitowoc, WI to Green Bay, WIbus
- Fly from Green Bay (GRB) to Des Moines (DSM)plane GRB - DSM
6h$177–798Bus to General Mitchell International Airport, fly
- Take the bus from Manitowoc Amtrak Bus Stop to Milwaukeebus
- Fly from General Mitchell International Airport (MKE) to Des Moines (DSM)plane MKE - DSM
7h 32m$200–1,270Bus, bus to Chicago O'Hare International Airport, fly
- Take the bus from Manitowoc Amtrak Bus Stop to Milwaukeebus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
7h 9m$153–728Bus, train
- Take the bus from Manitowoc Amtrak Bus Stop to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
11h 55m$83–204Bus via Saint Paul
- Take the bus from Manitowoc Amtrak Bus Stop to St. Paul-Minneapolisbus Amtrak Thruway Connecting Service
- Take the bus from MSP Airport to Des Moinesbus Jefferson 803
14h 25m
Appleton International Airport (ATW) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Manitowoc to Des Moines is to drive which costs $70 - $110 and takes 7h 45m.
The fastest way to get from Manitowoc to Des Moines is to taxi and fly which takes 5h and costs $240 - $900.
The distance between Manitowoc and Des Moines is 379 miles. The road distance is 402.7 miles.
The best way to get from Manitowoc to Des Moines without a car is to bus which takes 11h 33m and costs $80 - $180.
It takes approximately 5h to get from Manitowoc to Des Moines, including transfers.
Yes, the driving distance between Manitowoc to Des Moines is 403 miles. It takes approximately 7h 45m to drive from Manitowoc to Des Moines.
There are 241+ hotels available in Des Moines.
What companies run services between Manitowoc, WI, USA and Des Moines, IA, USA?
You can take a vehicle from Manitowoc to Des Moines via Manitowoc and Chicago Bus Station in around 11h 33m.
- Website
- united.com
Flights from Appleton International Airport to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $110–700
Flights from Green Bay to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $110–700
Flights from General Mitchell International Airport to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $160–1,100
Flights from General Mitchell International Airport to Des Moines via Denver
- Ave. Duration
- 7h 58m
- When
- Every day
- Estimated price
- $360–1,700
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–600
- Website
- aa.com
Flights from Appleton International Airport to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $110–700
Flights from Green Bay to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $110–700
Flights from General Mitchell International Airport to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $160–1,100
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $80–600
- Website
- delta.com
Flights from Appleton International Airport to Des Moines via Minneapolis
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $110–700
Flights from Appleton International Airport to Des Moines via Detroit
- Ave. Duration
- 6h 5m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $150–850
Flights from Green Bay to Des Moines via Minneapolis
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $110–700
Flights from Green Bay to Des Moines via Detroit
- Ave. Duration
- 5h 53m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $150–850
Flights from General Mitchell International Airport to Des Moines via Minneapolis
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $190–1,200
Flights from General Mitchell International Airport to Des Moines via Atlanta
- Ave. Duration
- 6h 59m
- When
- Every day
- Estimated price
- $340–1,700
Flights from General Mitchell International Airport to Des Moines via Detroit
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $230–1,300
- Website
- southwest.com
Flights from General Mitchell International Airport to Des Moines via St. Louis
- Ave. Duration
- 4h 20m
- When
- Monday to Friday
- Estimated price
- $190–1,200
Flights from General Mitchell International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 6h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–1,100
Flights from General Mitchell International Airport to Des Moines via Denver
- Ave. Duration
- 7h 35m
- When
- Every day
- Estimated price
- $360–1,700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Manitowoc to Chicago Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $40–95
- Website
- https://www.greyhound.com/
Bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
- Phone
- +1 989-725-5105
- Website
- indiantrails.com
Bus from Manitowoc, WI to Green Bay, WI
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $7–23
- Website
- https://indiantrails.com
Bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- https://indiantrails.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Manitowoc, WI to Green Bay, WI
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Bus from Manitowoc Amtrak Bus Stop to St. Paul-Minneapolis
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-236-1240
- Website
- golamers.com
Bus from Manitowoc, WI to Green Bay, WI
- Ave. Duration
- 55 min
- Frequency
- Twice a week
- Estimated price
- $14–23
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
Bus from Manitowoc Amtrak Bus Stop to Milwaukee
- Ave. Duration
- 2h
- Frequency
- Twice a week
- Estimated price
- $21–50
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–38
- Schedules at
- coachusa.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from MSP Airport to Des Moines
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $23–110
- Book at
- https://www.jeffersonlines.com
- Ave. Duration
- 1h 16m
- Estimated price
- $110–140
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