There are 8 ways to get from Manhattan to Syracuse, Ny by bus (Flixbus, Greyhound), train, car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from New York Midtown to Syracuse Bus StationFlixBus 2686 / ...
5h 5m$40–170Train
- Take the train from New York Penn Station to SyracuseVIA Rail
5h 34m$40–100Drive 252.8 mi
- Drive from Manhattan to Syracuse, Ny252.8 mi
4h 37m$47–67Fly Laguardia Airport to Syracuse Hancock International Airport
- Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)LGA - SYR
4h 26m$64–465Train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport
- Take the train from Grand Central Terminal to Jamaica
- Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)JFK - SYR
4h 29m$70–436Train to Newark Liberty International Airport, fly to Syracuse Hancock International Airport
- Take the train from New York Penn Station to Newark Airport Railroad Station
- Fly from Newark Liberty International Airport (EWR) to Syracuse Hancock International Airport (SYR)EWR - SYR
4h 25m$71–436Fly John F. Kennedy International Airport to Ithaca Tompkins Regional Airport, bus
- Fly from John F. Kennedy International Airport (JFK) to Ithaca Tompkins Regional Airport (ITH)JFK - ITH
- Take the bus from Ithaca to Syracuse Bus Station
6h 30m$66–297Fly Laguardia Airport to Rochester, bus
- Fly from Laguardia Airport (LGA) to Rochester (ROC)LGA - ROC
- Take the bus from Rochester, NY to Syracuse, NY
6h 41m$155–513
Manhattan to Syracuse, Ny by bus
Questions & Answers
The cheapest way to get from Manhattan to Syracuse, Ny is to drive which costs $45 - $70 and takes 4h 37m.
The fastest way to get from Manhattan to Syracuse, Ny is to train and fly which takes 4h 25m and costs $70 - $440.
Yes, there is a direct bus departing from New York Midtown and arriving at Syracuse Bus Station station. Services depart every two hours, and operate every day. The journey takes approximately 5h 5m.
Yes, there is a direct train departing from New York Penn Station station and arriving at Syracuse. Services depart once daily, and operate every day. The journey takes approximately 5h 34m.
The distance between Manhattan and Syracuse, Ny is 285 miles. The road distance is 254.3 miles.
The best way to get from Manhattan to Syracuse, Ny without a car is to bus which takes 5h 5m and costs $40 - $170.
The bus from New York Midtown to Syracuse Bus Station takes 5h 5m including transfers and departs every two hours.
Manhattan to Syracuse, Ny bus services, operated by Flixbus USA, depart from New York Midtown station.
Manhattan to Syracuse, Ny train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from Manhattan to Syracuse, Ny is to bus which takes 5h 5m and costs $40 - $170. Alternatively, you can train, which costs $40 - $100 and takes 5h 34m, you could also fly, which costs $60 - $470 and takes 4h 26m.
What companies run services between Manhattan, NY, USA and Syracuse, Ny, NY, USA?
Flixbus USA operates a bus from New York Midtown to Syracuse Bus Station every 4 hours. Tickets cost $40–90 and the journey takes 5h 5m. Two other operators also service this route. Alternatively, VIA Rail operates a train from New York Penn Station to Syracuse once daily. Tickets cost $40–100 and the journey takes 5h 34m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- delta.com
Flights from Laguardia Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $60–450
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $55–410
Flights from John F. Kennedy International Airport to Ithaca Tompkins Regional Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $35–250
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $55–390
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $55–410
- Website
- united.com
Flights from Newark Liberty International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $55–410
Flights from Laguardia Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–460
- Website
- aa.com
Flights from Laguardia Airport to Rochester via Reagan Washington
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $75–460
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from New York Penn Station to Syracuse
- Ave. Duration
- 5h 34m
- Frequency
- Once daily
- Estimated price
- $40–100
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $50–100
- Economy Adult - Advanced Booking
- $50–85
- Economy Escape Advanced Booking - Adult
- $40–60
- Phone
- +1-718-217-5477
- Website
- mta.info
Train from Grand Central Terminal to Jamaica
- Ave. Duration
- 21 min
- Frequency
- Every 15 minutes
- Estimated price
- $4–9
- Website
- https://www.mta.info/agency/long-island-rail-road
- Schedules at
- https://www.mta.info/agency/long-island-rail-road/timetables
- Off-Peak
- $4–7
- Peak
- $5–9
- Phone
- +1 973-275-5555
- Website
- njtransit.com
Train from New York Penn Station to Newark Airport Railroad Station
- Ave. Duration
- 24 min
- Frequency
- Every 20 minutes
- Estimated price
- $15–19
- Website
- https://www.njtransit.com/
- Schedules at
- https://www.njtransit.com/bus-to
- Adult Airport
- $15–19
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from New York Midtown to Syracuse Bus Station
- Ave. Duration
- 5h 5m
- Frequency
- Every 4 hours
- Estimated price
- $40–90
- Schedules at
- flixbus.com
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $17–29
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from New York Midtown to Syracuse Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–70
- Website
- https://www.greyhound.com/
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from New York Midtown to Syracuse Bus Station
- Ave. Duration
- 5h
- Frequency
- 4 times a day
- Estimated price
- $40–170
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–160
- Flexible
- $75–170
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Rochester, NY to Syracuse, NY
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a week
- Estimated price
- $20–60
- Website
- https://www.ourbus.com
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More Questions & Answers
Manhattan to Syracuse, Ny bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
Manhattan to Syracuse, Ny train services, operated by VIA Rail, arrive at Syracuse station.
Yes, the driving distance between Manhattan to Syracuse, Ny is 254 miles. It takes approximately 4h 37m to drive from Manhattan to Syracuse, Ny.
Book your Manhattan to Syracuse, Ny train tickets online with Omio.
Book your Manhattan to Syracuse, Ny bus tickets online with Omio and FlixBus.
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