There are 7 ways to get from Manhattan to St. Louis by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from New York La Guardia  •  4h 49m

  1. Fly from New York La Guardia (LGA) to St. Louis (STL) LGA - STL

$108 - $303

Cheapest option

Bus  •  25h 5m

  1. Take the bus from New York, Ny to Greyhound Bus Station St. Louis 1683 / ...

$100 - $150

5 alternative options

Fly from Newark  •  5h 14m

  1. Fly from Newark (EWR) to St. Louis (STL) EWR - STL

$122 - $416

Fly from New York JFK  •  7h 18m

  1. Fly from New York JFK (JFK) to St. Louis (STL) JFK - STL

$115 - $377

Train to Philadelphia, fly  •  6h 26m

  1. Take the train from New York Penn Station to 30th Street Train Station
  2. Fly from Philadelphia (PHL) to St. Louis (STL) PHL - STL

$150 - $568

Train  •  26h 49m

  1. Take the train from New York Penn Station to Chicago Union Station Lake Shore Limited / ...
  2. Take the train from Chicago Union Station to St. Louis Gateway Station Lincoln Service / ...

$138 - $203

Drive  •  16h 14m

  1. Drive from Manhattan to St. Louis 962 miles

$90 - $140

Questions & Answers

Travel restrictions may apply and transportation services are subject to change. Please check before you travel.

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The cheapest way to get from Manhattan to St. Louis is to drive which costs $90 - $140 and takes 16h 14m.

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The quickest way to get from Manhattan to St. Louis is to fly which costs $100 - $310 and takes 4h 49m.

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Yes, there is a direct bus departing from New York, Ny and arriving at Greyhound Bus Station St. Louis station. Services depart five times a day, and operate every day. The journey takes approximately 25h 5m.

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No, there is no direct train from Manhattan to St. Louis station. However, there are services departing from 86 St and arriving at St. Louis Gateway Station via New York Penn Station and Chicago Union Station. The journey, including transfers, takes approximately 26h 49m.

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The distance between Manhattan and St. Louis is 879 miles. The road distance is 962 miles.

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The best way to get from Manhattan to St. Louis without a car is to bus which takes 25h 5m and costs $100 - $150.

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It takes approximately 4h 49m to get from Manhattan to St. Louis, including transfers.

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Manhattan to St. Louis bus services, operated by Greyhound USA, depart from New York, Ny station.

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Manhattan to St. Louis train services, operated by Amtrak, depart from New York Penn Station.

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What companies run services between Manhattan, NY, USA and St. Louis, MO, USA?

Southwest Airlines, American Airlines and three other airlines fly from Manhattan to St. Louis hourly. Alternatively, Greyhound USA operates a bus from New York, Ny to Greyhound Bus Station St. Louis 5 times a day. Tickets cost $100 - $150 and the journey takes 25h 5m.

Airlines
Delta
Website
delta.com
Flights from New York La Guardia to St. Louis
Ave. Duration
3h
When
Every day
Estimated price
$190 - $600
Flights from Newark to St. Louis via Detroit
Ave. Duration
4h 34m
When
Every day
Estimated price
$170 - $550
Flights from New York JFK to St. Louis via Detroit
Ave. Duration
5h 28m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $550
Flights from New York JFK to St. Louis via Atlanta
Ave. Duration
5h 59m
When
Every day
Estimated price
$180 - $600
Flights from New York JFK to St. Louis via Covington
Ave. Duration
5h 14m
When
Monday to Friday
Estimated price
$170 - $550
Flights from New York JFK to St. Louis via Minneapolis
Ave. Duration
7h 8m
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to St. Louis via Detroit
Ave. Duration
4h 28m
When
Monday to Friday
Estimated price
$220 - $750
American Airlines
Website
aa.com
Flights from New York La Guardia to St. Louis
Ave. Duration
2h 59m
When
Every day
Estimated price
$100 - $390
Flights from New York JFK to St. Louis via Charlotte
Ave. Duration
5h 22m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $400
Flights from New York JFK to St. Louis via Reagan Washington
Ave. Duration
6h 20m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $400
Flights from New York JFK to St. Louis via Chicago O'Hare
Ave. Duration
6h 50m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $400
Flights from New York JFK to St. Louis via Miami
Ave. Duration
7h 46m
When
Every day
Estimated price
$100 - $400
Flights from New York JFK to St. Louis via Philadelphia
Ave. Duration
7h 49m
When
Every day
Estimated price
$100 - $400
Flights from New York JFK to St. Louis via Dallas/Ft.Worth
Ave. Duration
8h 10m
When
Monday, Tuesday, Wednesday, Thursday and Sunday
Estimated price
$100 - $400
Flights from Philadelphia to St. Louis
Ave. Duration
2h 34m
When
Every day
Estimated price
$110 - $550
Flights from Philadelphia to St. Louis via Reagan Washington
Ave. Duration
4h 21m
When
Monday to Friday
Estimated price
$110 - $550
Southwest Airlines
Website
southwest.com
Flights from New York La Guardia to St. Louis
Ave. Duration
2h 47m
When
Every day
Estimated price
$110 - $480
Flights from New York La Guardia to St. Louis via Chicago Midway
Ave. Duration
4h 35m
When
Saturday
Estimated price
$110 - $480
Flights from Philadelphia to St. Louis
Ave. Duration
2h 32m
When
Every day
Estimated price
$110 - $470
Flights from Philadelphia to St. Louis via Chicago Midway
Ave. Duration
4h 16m
When
Every day
Estimated price
$110 - $480
Flights from Philadelphia to St. Louis via Nashville
Ave. Duration
4h 15m
When
Monday to Friday
Estimated price
$110 - $480
United Airlines
Website
united.com
Flights from Newark to St. Louis
Ave. Duration
2h 50m
When
Every day
Estimated price
$130 - $400
Flights from Newark to St. Louis via Toronto
Ave. Duration
4h 40m
When
Every day
Estimated price
$140 - $410
Flights from Newark to St. Louis via Washington Dulles
Ave. Duration
4h 49m
When
Monday to Saturday
Estimated price
$130 - $400
Flights from Newark to St. Louis via Chicago O'Hare
Ave. Duration
4h 49m
When
Every day
Estimated price
$130 - $400
Air Canada
Website
aircanada.com
Flights from New York La Guardia to St. Louis via Toronto
Ave. Duration
4h 40m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $420
Flights from Newark to St. Louis via Toronto
Ave. Duration
4h 40m
When
Every day
Estimated price
$140 - $410
Flights from Newark to St. Louis via Chicago O'Hare
Ave. Duration
4h 49m
When
Every day
Estimated price
$130 - $400
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New York Penn Station to 30th Street Train Station
Ave. Duration
1h 8m
Frequency
Hourly
Estimated price
$27 - $40
Website
amtrak.com
Coach Seat
$27 - $40
Premium
$180 - $260
Flexi Coach Seat
$40 - $65
Business Seat
$40 - $60
Train from New York Penn Station to Chicago Union Station
Ave. Duration
19h 10m
Frequency
Once daily
Estimated price
$95 - $140
Website
amtrak.com
Coach Seat
$95 - $140
Premium
$320 - $440
Flexi Coach Seat
$190 - $290
Business Seat
$210 - $300
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5h 30m
Frequency
5 times a day
Estimated price
$40 - $60
Website
amtrak.com
Coach Seat
$40 - $60
Premium
$210 - $300
Flexi Coach Seat
$75 - $110
Business Seat
$75 - $110
Amtrak Northeast Regional

Amtrak’s Northeast Regional train service serves the US’ busy northeast corridor from Virginia to Massachusetts; major stops include Boston, Providence, New York City, Philadelphia, Washington DC and Baltimore. Amenities include Wi-Fi, a quiet car, cafe and business-class seating, and travelling with a small dog or cat is permitted. Book at least 14 days in advance for a cheaper Saver Fare.

Rome2rio's guide to Amtrak Northeast Regional
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New York Penn Station to 30th Street Train Station
Ave. Duration
1h 23m
Frequency
Hourly
Estimated price
$40 - $85
Website
amtrak.com
Reserved Coach Seat
$40 - $85
Business Class Seat
$65 - $130
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New York, Ny to Greyhound Bus Station St. Louis
Ave. Duration
25h 5m
Frequency
5 times a day
Estimated price
$100 - $150
Website
greyhound.com
Economy
$100 - $150
Flexible
$150 - $220

Want to know more about travelling around United States

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More Questions & Answers

The best way to get from Manhattan to St. Louis is to fly which takes 4h 49m and costs $100 - $310. Alternatively, you can bus, which costs $100 - $150 and takes 25h 5m, you could also train, which costs $130 - $210 and takes 26h 49m.

Mode details

The quickest flight from New York La Guardia Airport to St. Louis Airport is the direct flight which takes 2h 40m.

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Manhattan to St. Louis bus services, operated by Greyhound USA, arrive at Greyhound Bus Station St. Louis.

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St. Louis is 1h behind Manhattan. It is currently 1:05 PM in Manhattan and 12:05 PM in St. Louis.

Manhattan to St. Louis train services, operated by Amtrak, arrive at St. Louis Gateway Station.

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Yes, the driving distance between Manhattan to St. Louis is 962 miles. It takes approximately 16h 14m to drive from Manhattan to St. Louis.

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Air Canada, American Airlines, Southwest Airlines and Delta offer flights from New York La Guardia Airport to St. Louis Airport.

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Book your Manhattan to St. Louis bus tickets online with Greyhound.

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There are 363+ hotels available in St. Louis. Prices start at $100 USD per night.

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