There are 6 ways to get from Manhattan to St. Louis by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from New York La Guardia  •  4 h 42 min

  1. Fly from New York La Guardia (LGA) to St. Louis (STL) LGA - STL

$148 - $363

Cheapest option

Bus  •  25 h 5 min

  1. Take the bus from New York, Ny to St Louis, Mo 1683 / ...

$95 - $250

4 alternative options

Fly from Newark  •  4 h 46 min

  1. Fly from Newark (EWR) to St. Louis (STL) EWR - STL

$160 - $450

Train to Philadelphia, fly  •  6 h 14 min

  1. Take the train from New York Penn Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to St. Louis (STL) PHL - STL

$248 - $613

Train  •  26 h 48 min

  1. Take the train from New York Penn Station to Chicago Union Station Lake Shore Limited
  2. Take the train from Chicago Union Station to St. Louis Gateway Station Lincoln Service / ...

$173 - $503

Drive  •  16 h 12 min

  1. Drive from Manhattan to St. Louis 961.5 miles

$90 - $140

Questions & Answers

Yes, there is a direct bus departing from New York, Ny and arriving at St Louis, Mo. Services depart every 30 minutes, and operate every day. The journey takes approximately 25 h 5 min.

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The distance between Manhattan and St. Louis is 879 miles. The road distance is 961.5 miles.

Get driving directions

The best way to get from Manhattan to St. Louis without a car is to bus which takes 25 h 5 min and costs .

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It takes approximately 4 h 42 min to get from Manhattan to St. Louis, including transfers.

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Manhattan to St. Louis bus services, operated by Greyhound USA, depart from New York, Ny station.

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The best way to get from Manhattan to St. Louis is to fly which takes 4 h 42 min and costs . Alternatively, you can bus, which costs and takes 25 h 5 min, you could also train, which costs and takes 26 h 48 min.

Mode details

The quickest flight from New York La Guardia Airport to St. Louis Airport is the direct flight which takes 2 h 35 min.

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Manhattan to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

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St. Louis is 1 h behind Manhattan. It is currently 11:16 PM in Manhattan and 10:16 PM in St. Louis.

Yes, the driving distance between Manhattan to St. Louis is 961 miles. It takes approximately 16 h 12 min to drive from Manhattan to St. Louis.

Get driving directions

Map of how to get from Manhattan to St. Louis.
Launch map view
  • Distance: 879.4 miles
  • Duration: 4 h 42 min

What companies run services between Manhattan, NY, USA and St. Louis, MO, USA?

Southwest Airlines, American Airlines and three other airlines fly from Manhattan to St. Louis hourly. Alternatively, Greyhound USA operates a bus from Manhattan to St. Louis every 30 minutes. Tickets cost $95 - $250 and the journey takes 25 h 5 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from New York La Guardia to St. Louis
Ave. Duration
2 h 41 min
When
Every day
Estimated price
$320 - $750
Flights from New York La Guardia to St. Louis via Chicago Midway
Ave. Duration
4 h 30 min
When
Monday to Friday
Estimated price
$320 - $750
Flights from New York La Guardia to St. Louis via Nashville
Ave. Duration
4 h 35 min
When
Monday to Friday
Estimated price
$320 - $750
Flights from Newark to St. Louis
Ave. Duration
2 h 41 min
When
Every day
Estimated price
$300 - $950
Flights from Newark to St. Louis via Chicago Midway
Ave. Duration
4 h 27 min
When
Monday to Friday
Estimated price
$300 - $950
Flights from Philadelphia to St. Louis
Ave. Duration
2 h 31 min
When
Every day
Estimated price
$340 - $900
Flights from Philadelphia to St. Louis via Nashville
Ave. Duration
4 h 20 min
When
Sunday
Estimated price
$340 - $900
Flights from Philadelphia to St. Louis via Chicago Midway
Ave. Duration
4 h 20 min
When
Saturday
Estimated price
$340 - $900
Delta
Website
delta.com
Flights from New York La Guardia to St. Louis
Ave. Duration
2 h 56 min
When
Every day
Estimated price
$230 - $700
Flights from New York La Guardia to St. Louis via Detroit
Ave. Duration
4 h 24 min
When
Monday to Friday
Estimated price
$230 - $700
Flights from Newark to St. Louis via Detroit
Ave. Duration
4 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $750
Flights from Philadelphia to St. Louis via Detroit
Ave. Duration
4 h 6 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $800
United Airlines
Website
united.com
Flights from Newark to St. Louis
Ave. Duration
2 h 53 min
When
Every day
Estimated price
$190 - $950
Flights from Philadelphia to St. Louis via Washington Dulles
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$280 - $1,100
American Airlines
Website
aa.com
Flights from New York La Guardia to St. Louis
Ave. Duration
2 h 50 min
When
Every day
Estimated price
$230 - $650
Flights from Philadelphia to St. Louis
Ave. Duration
2 h 29 min
When
Every day
Estimated price
$200 - $750
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Philadelphia 30th Street Station
Ave. Duration
1 h 7 min
Frequency
Every 30 minutes
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Chicago Union Station
Ave. Duration
19 h 10 min
Frequency
Once daily
Estimated price
$120 - $370
Website
amtrak.com
Coach Seat
$120 - $190
Flexi Coach Seat
$220 - $330
Business Coach Seat
$260 - $370
Room
$500 - $700
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5 h 30 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New York, Ny to St Louis, Mo
Ave. Duration
25 h 5 min
Frequency
Every 30 minutes
Estimated price
$95 - $250
Website
greyhound.com
Economy
$95 - $160
Flexible
$190 - $250

Want to know more about travelling around United States

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More Questions & Answers

American Airlines, Delta and Southwest Airlines offer flights from New York La Guardia Airport to St. Louis Airport.

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Book your Manhattan to St. Louis bus tickets online with Greyhound.

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There are 193+ hotels available in St. Louis. Prices start at $70 USD per night.

More details

The best way to get from Manhattan to Newark Airport is to shuttle which takes 20 min and costs .

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