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How to get fromManhattan to Lexingtonby plane, car, bus (Greyhound), train, bus, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Manhattan to Lexington by plane, car, bus (Greyhound), train, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Louisville International Airport, drive

    best
    1. Fly from Laguardia Airport (LGA) to Louisville International Airport (SDF)plane plane LGA - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    5h 22m
    $137–728

  2. Drive 698.7 mi

    cheapest
    1. Drive from Manhattan to Lexingtoncar car 698.7 mi
    12h 10m
    $128–185

  3. Bus via Reading

    1. Take the bus from New York, NY to Sharonville/Cincinnati, OHbus bus Nyc
    2. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus Greyhound US0110 / ...
    15h 36m
    $174–197

  4. Train, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus Greyhound US0120
    28h 17m

  5. Fly Newark Liberty International Airport to Louisville International Airport, drive

    1. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    5h 23m
    $134–598

  6. Fly Laguardia Airport to Blue Grass Airport

    1. Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)plane plane LGA - LEX
    6h 1m
    $185–959

  7. Bus

    1. Take the bus from New York Midtown to Dayton Trotwood Bus Stationbus bus FlixBus N2642
    2. Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus bus Greyhound US0110
    19h 27m
    $160–258

  8. Bus #2

    1. Take the bus from Port Authority Bus Terminal to Dayton Trotwood Bus Stationbus bus Greyhound US0421
    2. Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus bus Greyhound US0110
    20h 43m
    $147–272

Laguardia Airport (LGA) to Louisville International Airport (SDF) flights

Calendar59Weekly Planes
Duration3h 45mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Lexington.ExpandLaunch map view
  • Distance: 744 mi
  • Duration: 5h 22m

What companies run services between Manhattan, NY, USA and Lexington, KY, USA?

You can take a subway from 86th Street to Lexington via Canal St, New York, NY, Sharonville/Cincinnati, OH, Cincinnati Bus Station, and Lexington Bus Stop in around 15h 36m. Alternatively, Delta and American Airlines fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX) every 2 hours.

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