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How to get fromManhattan to Iowaby plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

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There are 11 ways to get from Manhattan to Iowa by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Newark Liberty International Airport to Des Moines

    best
    1. Fly from Newark Liberty International Airport (EWR) to Des Moines (DSM)plane plane EWR - DSM
    4h 37m
    $187–798

  2. Fly Laguardia Airport to Quad City International Airport

    cheapest
    1. Fly from Laguardia Airport (LGA) to Quad City International Airport (MLI)plane plane LGA - MLI
    7h 46m
    $105–559

  3. Bus

    1. Take the bus from New York Midtown to Chicago Bus Stationbus bus FlixBus N2641 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    24h 30m
    $194–334

  4. Train, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    28h 46m
    $371–768

  5. Drive 1,107.9 mi

    1. Drive from Manhattan to Des Moinescar car 1,107.9 mi
    18h 28m
    $203–292

  6. Fly Laguardia Airport to Des Moines

    1. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    4h 42m
    $210–978

  7. Fly Laguardia Airport to Omaha

    1. Fly from Laguardia Airport (LGA) to Omaha (OMA)plane plane LGA - OMA
    5h 1m
    $188–787

  8. Train to Philadelphia International Airport, fly to Des Moines

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    5h 56m
    $261–1,720

  9. Train to Philadelphia International Airport, fly to Omaha

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Omaha (OMA)plane plane PHL - OMA
    6h 25m
    $229–1,479

  10. Bus via Indianapolis (Greyhound)

    1. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    28h 5m
    $202–381

  11. Train, bus via Galesburg

    1. Take the train from 125th Street - Harlem to Croton-Harmontrain train
    2. Take the train from Croton-Harmon Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    30h 24m
    $398–797

Newark Liberty International Airport (EWR) to Des Moines (DSM) flights

Calendar92Weekly Planes
Duration5h 16mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Iowa.ExpandLaunch map view
  • Distance: 1,033.7 mi
  • Duration: 4h 37m

What companies run services between Manhattan, NY, USA and Iowa, USA?

Allegiant Air, Delta, and two other airlines fly from Newark Liberty International Airport (EWR) to Des Moines (DSM) hourly. Alternatively, you can take a bus from New York Midtown to Des Moines via Chicago Bus Station and Des Moines in around 24h 30m.

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