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How to get fromManhattan to Iowaby plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Find Transport to Iowa

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There are 11 ways to get from Manhattan to Iowa by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Des Moines

    best
    1. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    4h 46m
    $240–1,128

  2. Fly Laguardia Airport to Quad City International Airport

    cheapest
    1. Fly from Laguardia Airport (LGA) to Quad City International Airport (MLI)plane plane LGA - MLI
    7h 45m
    $105–559

  3. Bus

    1. Take the bus from New York Midtown to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    28h
    $196–342

  4. Train, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    28h 46m
    $336–728

  5. Drive 1,107.8 mi

    1. Drive from Manhattan to Des Moinescar car 1,107.8 mi
    18h 28m
    $203–292

  6. Fly Newark Liberty International Airport to Des Moines

    1. Fly from Newark Liberty International Airport (EWR) to Des Moines (DSM)plane plane EWR - DSM
    4h 47m
    $197–848

  7. Fly Laguardia Airport to Omaha

    1. Fly from Laguardia Airport (LGA) to Omaha (OMA)plane plane LGA - OMA
    4h 54m
    $248–1,137

  8. Train to Philadelphia International Airport, fly to Des Moines

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    5h 57m
    $281–1,820

  9. Train to Philadelphia International Airport, fly to Omaha

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Omaha (OMA)plane plane PHL - OMA
    6h 32m
    $289–1,829

  10. Bus via Indianapolis (Greyhound)

    1. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    28h 5m
    $217–417

  11. Train, bus via Bloomington

    1. Take the train from 125th Street - Harlem to Croton-Harmontrain train
    2. Take the train from Croton-Harmon Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    4. Take the bus from Bloomington-Normal to Des Moinesbus bus
    31h 26m
    $359–802

Laguardia Airport (LGA) to Des Moines (DSM) flights

Calendar85Weekly Planes
Duration5h 6mAverage Duration
Ticket$224Cheapest Price
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Questions & Answers

What companies run services between Manhattan, NY, USA and Iowa, USA?

American Airlines, Delta, and two other airlines fly from Laguardia Airport (LGA) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from New York Midtown to Des Moines via Chicago Bus Station and Des Moines in around 28h.

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