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How to get fromManhattan to Iowaby plane, bus (Flixbus, Greyhound), train, bus or car

Find Transport to Iowa

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There are 7 ways to get from Manhattan to Iowa by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Des Moines

    best
    1. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    4h 50m
    $105–478

  2. Fly Laguardia Airport to Quad City International Airport

    cheapest
    1. Fly from Laguardia Airport (LGA) to Quad City International Airport (MLI)plane plane LGA - MLI
    7h 50m
    $80–419

  3. Bus

    1. Take the bus from New York Midtown to Chicago Bus Stationbus bus FlixBus N2640
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S
    29h 55m
    $183–327

  4. Train, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S
    30h 43m
    $306–678

  5. Drive 1,107.8 mi

    1. Drive from Manhattan to Des Moinescar car 1,107.8 mi
    18h 28m
    $203–292

  6. Fly Laguardia Airport to Omaha

    1. Fly from Laguardia Airport (LGA) to Omaha (OMA)plane plane LGA - OMA
    5h 9m
    $278–1,337

  7. Fly Newark Liberty International Airport to Quad City International Airport

    1. Fly from Newark Liberty International Airport (EWR) to Quad City International Airport (MLI)plane plane EWR - MLI
    7h 53m
    $87–389

Laguardia Airport (LGA) to Des Moines (DSM) flights

Calendar59Weekly Planes
Duration5h 6mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

What companies run services between Manhattan, NY, USA and Iowa, USA?

American Airlines, Delta, and two other airlines fly from Laguardia Airport (LGA) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from New York Midtown to Des Moines via Chicago Bus Station and Des Moines in around 29h 55m.

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