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How to get fromManhattan to Iowaby plane, bus (Flixbus, Greyhound), train, bus, car or bus (Greyhound)

Find Transport to Iowa

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There are 9 ways to get from Manhattan to Iowa by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Des Moines

    best
    1. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    4h 46m
    $220–1,028

  2. Fly Laguardia Airport to Quad City International Airport

    cheapest
    1. Fly from Laguardia Airport (LGA) to Quad City International Airport (MLI)plane plane LGA - MLI
    7h 49m
    $90–449

  3. Bus

    1. Take the bus from New York Midtown to Chicago Bus Stationbus bus FlixBus N2641 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    24h 30m
    $173–312

  4. Train, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    28h 46m
    $321–728

  5. Drive 1,107.8 mi

    1. Drive from Manhattan to Des Moinescar car 1,107.8 mi
    18h 28m
    $203–292

  6. Fly Laguardia Airport to Omaha

    1. Fly from Laguardia Airport (LGA) to Omaha (OMA)plane plane LGA - OMA
    5h 8m
    $238–1,137

  7. Fly Newark Liberty International Airport to Quad City International Airport

    1. Fly from Newark Liberty International Airport (EWR) to Quad City International Airport (MLI)plane plane EWR - MLI
    7h 46m
    $92–399

  8. Bus via Indianapolis (Greyhound)

    1. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    28h 5m
    $215–410

  9. Train, bus via Bloomington

    1. Take the train from 125th Street - Harlem to Croton-Harmontrain train
    2. Take the train from Croton-Harmon Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    4. Take the bus from Bloomington-Normal to Des Moinesbus bus
    31h 25m
    $344–742

Laguardia Airport (LGA) to Des Moines (DSM) flights

Calendar91Weekly Planes
Duration5h 2mAverage Duration
Ticket$199Cheapest Price
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Questions & Answers

What companies run services between Manhattan, NY, USA and Iowa, USA?

American Airlines, Delta, and two other airlines fly from Laguardia Airport (LGA) to Des Moines (DSM) hourly. Alternatively, you can take a bus from New York Midtown to Des Moines via Chicago Bus Station and Des Moines in around 24h 30m.

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Want to know more about travelling around United States

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