Greyhound USA operates a bus from Manhattan to Groton twice daily. Tickets cost $18 - $45 and the journey takes 3 h 50 min. Alternatively, New York City Transit (MTA) operates a train from Manhattan to Groton every 10 minutes. Tickets cost $3 and the journey takes 9 min. Amtrak Northeast Regional also services this route every 2 hours.
From New York, NY bus to New London, CT. 3 h 50 min $34. From 86 St subway to New York Penn Station then train to New London Union Station Amtrak. 4 h 3 min $122. From 83rd & Lex. bus to Orient Point then car ferry to New London. 5 h 25 min $69. From Manhattan drive to Groton. 2 h 22 min $15.