There are 11 ways to get from Manhattan to Florida Keys by plane, train, shuttle, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Newark Liberty International Airport to Key West International Airport
best- Fly from Newark Liberty International Airport (EWR) to Key West International Airport (EYW)plane EWR - EYW
7h 55m$167–506Train to Philadelphia International Airport, fly to Key West International Airport
cheapest- Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to Key West International Airport (EYW)plane PHL - EYW
9h 32m$145–1,265Train, shuttle
- Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain Silver Meteor
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
34h 21m$320–744Bus
- Take the bus from Port Authority Bus Terminal to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
39h 10m$167–414Drive 1,420.9 mi
- Drive from Manhattan to Florida Keyscar 1,420.9 mi
24h 39m$260–375Fly Laguardia Airport to Key West International Airport
- Fly from Laguardia Airport (LGA) to Key West International Airport (EYW)plane LGA - EYW
8h 11m$160–546Fly Laguardia Airport to Miami International Airport, shuttle
- Fly from Laguardia Airport (LGA) to Miami International Airport (MIA)plane LGA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 17m$180–491Fly Newark Liberty International Airport to Miami International Airport, shuttle
- Fly from Newark Liberty International Airport (EWR) to Miami International Airport (MIA)plane EWR - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 13m$207–551Fly John F. Kennedy International Airport to Miami International Airport, shuttle
- Fly from John F. Kennedy International Airport (JFK) to Miami International Airport (MIA)plane JFK - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 21m$226–612Fly Laguardia Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Laguardia Airport (LGA) to Fort Lauderdale–Hollywood International Airport (FLL)plane LGA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 38m$200–461Fly Newark Liberty International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Newark Liberty International Airport (EWR) to Fort Lauderdale–Hollywood International Airport (FLL)plane EWR - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 35m$222–461
Manhattan to Florida Keys by bus and foot
Questions & Answers
The cheapest way to get from Manhattan to Florida Keys is to bus which costs $160 - $420 and takes 39h 10m.
The fastest way to get from Manhattan to Florida Keys is to fly which takes 7h 55m and costs $160 - $550.
No, there is no direct bus from Manhattan to Florida Keys. However, there are services departing from Port Authority Bus Terminal and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 39h 10m.
The distance between Manhattan and Florida Keys is 1240 miles. The road distance is 1429.2 miles.
The best way to get from Manhattan to Florida Keys without a car is to train and shuttle which takes 34h 21m and costs $320 - $750.
It takes approximately 7h 55m to get from Manhattan to Florida Keys, including transfers.
Manhattan to Florida Keys bus services, operated by Greyhound USA, depart from Port Authority Bus Terminal station.
The best way to get from Manhattan to Florida Keys is to fly which takes 7h 55m and costs $160 - $550. Alternatively, you can bus, which costs $160 - $420 and takes 39h 10m.
Manhattan to Florida Keys bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Manhattan to Florida Keys is 1429 miles. It takes approximately 24h 39m to drive from Manhattan to Florida Keys.
What companies run services between Manhattan, NY, USA and Florida Keys, FL, USA?
United Airlines, American Airlines, and two other airlines fly from Newark Liberty International Airport (EWR) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Port Authority Bus Terminal to Florida Keys via Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 39h 10m.
- Website
- aa.com
Flights from Newark Liberty International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $110–600
Flights from Laguardia Airport to Key West International Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $130–700
Flights from Laguardia Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $130–700
Flights from Philadelphia International Airport to Key West International Airport
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $130–700
Flights from Philadelphia International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $140–700
Flights from Laguardia Airport to Miami International Airport
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $90–470
Flights from Newark Liberty International Airport to Miami International Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $75–400
Flights from John F. Kennedy International Airport to Miami International Airport
- Ave. Duration
- 3h 24m
- When
- Every day
- Estimated price
- $80–410
Flights from John F. Kennedy International Airport to Miami International Airport via Raleigh/Durham
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $80–420
Flights from Laguardia Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 19m
- When
- Every day
- Estimated price
- $65–350
- Website
- delta.com
Flights from Laguardia Airport to Key West International Airport
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $130–700
Flights from Philadelphia International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $150–750
Flights from Laguardia Airport to Miami International Airport
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $90–470
Flights from John F. Kennedy International Airport to Miami International Airport
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $80–410
Flights from Laguardia Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- $65–350
Flights from Laguardia Airport to Fort Lauderdale–Hollywood International Airport via Raleigh/Durham
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $70–350
Flights from Newark Liberty International Airport to Fort Lauderdale–Hollywood International Airport via Raleigh/Durham
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $55–300
- Website
- united.com
Flights from Newark Liberty International Airport to Key West International Airport
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $110–600
Flights from Newark Liberty International Airport to Miami International Airport
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- $75–400
Flights from Newark Liberty International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- $55–290
- Website
- spirit.com
Flights from Newark Liberty International Airport to Key West International Airport via Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 6h 11m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $95–410
Flights from Laguardia Airport to Key West International Airport via Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 5h 56m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–420
Flights from Philadelphia International Airport to Key West International Airport via Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 5h 56m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–600
Flights from Laguardia Airport to Miami International Airport
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $45–300
Flights from Newark Liberty International Airport to Miami International Airport
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- $55–340
Flights from Laguardia Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- $45–250
Flights from Newark Liberty International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- $50–230
Flights from Newark Liberty International Airport to Fort Lauderdale–Hollywood International Airport via Charleston
- Ave. Duration
- 6h 16m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $50–230
- Website
- jetblue.com
Flights from Laguardia Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- $65–350
Flights from Newark Liberty International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- $55–290
- Website
- flyfrontier.com
Flights from Laguardia Airport to Miami International Airport
- Ave. Duration
- 3h 16m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $90–470
Flights from John F. Kennedy International Airport to Miami International Airport
- Ave. Duration
- 3h 19m
- When
- Every day
- Estimated price
- $80–410
- Website
- allegiantair.com
Flights from Newark Liberty International Airport to Key West International Airport via Knoxville
- Ave. Duration
- 6h 56m
- When
- Monday and Friday
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 29m
- Frequency
- Once daily
- Estimated price
- $160–550
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $18–260
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 33m
- Frequency
- Hourly
- Estimated price
- $12–230
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $12–230
- Business Class
- $60–270
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 10m
- Frequency
- Every 2 hours
- Estimated price
- $20–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $20–460
- First Class
- $130–600
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Port Authority Bus Terminal to Atlanta Bus Station
- Ave. Duration
- 18h 35m
- Frequency
- 4 times a day
- Estimated price
- $80–180
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $65–200
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $60–160
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 824+ hotels available in Florida Keys.








