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How to get fromManhattan to Durhamby bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

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There are 9 ways to get from Manhattan to Durham by bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Laguardia Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus

    best
    1. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus bus
    2. Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)plane plane LGA - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    4h 39m
    $129–453

  2. Bus

    cheapest
    1. Take the bus from New York Midtown to Durhambus bus FlixBus N2471 / ...
    10h 25m
    $85–140

  3. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain train Carolinian
    12h 51m
    $140–320

  4. Drive  487.1 mi

    1. Drive from Manhattan to Durhamcar car 487.1 mi
    8h 42m
    $89–129

  5. Bus to Newark Liberty International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    4h 50m
    $181–871

  6. Train to John F. Kennedy International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus

    1. Take the train from Grand Central Terminal to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Raleigh-Durham International Airport (RDU)plane plane JFK - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    4h 45m
    $400–1,324

  7. Fly Laguardia Airport to Piedmont Triad International Airport, train

    1. Fly from Laguardia Airport (LGA) to Piedmont Triad International Airport (GSO)plane plane LGA - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    5h 29m
    $186–977

  8. Train to Long Island Mac Arthur Airport, fly to Raleigh-Durham International Airport

    1. Take the train from New York Penn Station to Central Isliptrain train
    2. Fly from Long Island Mac Arthur Airport (ISP) to Raleigh-Durham International Airport (RDU)plane plane ISP - RDU
    6h 12m
    $152–366

  9. Train to Westchester County Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus

    1. Take the train from 125th Street - Harlem to White Plainstrain train
    2. Fly from Westchester County Airport (HPN) to Raleigh-Durham International Airport (RDU)plane plane HPN - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    6h 34m
    $137–722

Manhattan to Durham by bus

Calendar37Weekly Buses
Duration10h 25mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Durham.ExpandLaunch map view
  • Distance: 454.6 mi
  • Duration: 4h 39m

What companies run services between Manhattan, NY, USA and Durham, NC, USA?

Flixbus USA operates a bus from New York Midtown to Durham twice daily. Tickets cost $85–130 and the journey takes 10h 25m. Greyhound USA also services this route 3 times a day. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station once daily. Tickets cost $140–320 and the journey takes 12h 51m.

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