Rome2Rio

How to get fromManhattan to Durhamby train, plane, bus, bus (Flixbus, Greyhound), train (Amtrak) or car

Find Transport to Durham

See all options

There are 7 ways to get from Manhattan to Durham by train, plane, bus, bus (Flixbus, Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Newark Liberty International Airport, fly, bus, line 700 bus

    best
    1. Take the train from New York Penn Station to Newark Airport Railroad Stationtrain
    2. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)planeEWR - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    4h 48m
    $75–410

  2. Bus

    cheapest
    1. Take the bus from New York Midtown to DurhambusFlixBus N2470 / ...
    10h 25m
    $60–200

  3. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak StationtrainCarolinian
    11h 54m
    $95–350

  4. Drive 486.7 mi

    1. Drive from Manhattan to Durhamcar486.7 mi
    8h 37m
    $89–129

  5. Bus to Laguardia Airport, fly, bus, line 700 bus

    1. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
    2. Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)planeLGA - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    4h 55m
    $113–430

  6. Train to John F. Kennedy International Airport, fly, bus, line 700 bus

    1. Take the train from Grand Central Terminal to Jamaicatrain
    2. Fly from John F. Kennedy International Airport (JFK) to Raleigh-Durham International Airport (RDU)planeJFK - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    4h 59m
    $69–361

  7. Train to Westchester County Airport, fly, bus, line 700 bus

    1. Take the train from 125th Street - Harlem to White Plainstrain
    2. Fly from Westchester County Airport (HPN) to Raleigh-Durham International Airport (RDU)planeHPN - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus
    6h 41m
    $102–510

Manhattan to Durham by bus

Calendar40Weekly Buses
Duration10h 25mAverage Duration
Ticket$60Cheapest Price
See schedules

Questions & Answers

What companies run services between Manhattan, NY, USA and Durham, NC, USA?

Flixbus USA operates a bus from New York Midtown to Durham 3 times a day. Tickets cost $65–200 and the journey takes 10h 25m. Greyhound USA also services this route 3 times a day. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station once daily. Tickets cost $95–350 and the journey takes 11h 54m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Manhattan

Trips to Durham

Popular routes