There are 6 ways to get from Manhattan to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Newark Liberty International Airport
best- Fly from Newark Liberty International Airport (EWR) to Des Moines (DSM)plane EWR - DSM
4h 47m$197–898Bus
cheapest- Take the bus from New York Midtown to Chicago Bus Stationbus FlixBus N2640
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
27h 59m$132–327Train, bus
- Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain Lake Shore Limited / ...
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
28h 47m$163–567Drive 1,107.8 mi
- Drive from Manhattan to Des Moinescar 1,107.8 mi
18h 28m$203–292Fly from Laguardia Airport
- Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane LGA - DSM
5h$210–1,028Train to Philadelphia International Airport, fly
- Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane PHL - DSM
6h 8m$220–1,617
Manhattan to Des Moines by bus
Questions & Answers
The cheapest way to get from Manhattan to Des Moines is to bus which costs $130 - $330 and takes 27h 59m.
The fastest way to get from Manhattan to Des Moines is to fly which takes 4h 47m and costs $190 - $900.
No, there is no direct bus from Manhattan to Des Moines. However, there are services departing from New York Midtown and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 27h 59m.
The distance between Manhattan and Des Moines is 1040 miles. The road distance is 1114.3 miles.
The best way to get from Manhattan to Des Moines without a car is to bus which takes 27h 59m and costs $130 - $330.
It takes approximately 4h 47m to get from Manhattan to Des Moines, including transfers.
Manhattan to Des Moines bus services, operated by Flixbus USA, depart from New York Midtown station.
The best way to get from Manhattan to Des Moines is to fly which takes 4h 47m and costs $190 - $900. Alternatively, you can bus, which costs $130 - $330 and takes 27h 59m.
Manhattan to Des Moines bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Des Moines is 1h behind Manhattan. It is currently 2:32 PM in Manhattan and 1:32 PM in Des Moines.
What companies run services between Manhattan, NY, USA and Des Moines, IA, USA?
Allegiant Air, Delta, and two other airlines fly from Newark Liberty International Airport (EWR) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from New York Midtown to Des Moines via Chicago Bus Station in around 27h 59m.
- Website
- united.com
Flights from Newark Liberty International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $160–850
Flights from Laguardia Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Philadelphia International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $190–1,100
- Website
- aa.com
Flights from Newark Liberty International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $160–850
Flights from Laguardia Airport to Des Moines
- Ave. Duration
- 3h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $190–1,000
Flights from Laguardia Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Laguardia Airport to Des Moines via Reagan Washington
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Philadelphia International Airport to Des Moines
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Philadelphia International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $190–1,100
- Website
- delta.com
Flights from Newark Liberty International Airport to Des Moines via Detroit
- Ave. Duration
- 5h 8m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–850
Flights from Laguardia Airport to Des Moines
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Laguardia Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,100
Flights from Laguardia Airport to Des Moines via Detroit
- Ave. Duration
- 5h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–1,000
Flights from Philadelphia International Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Philadelphia International Airport to Des Moines via Detroit
- Ave. Duration
- 5h 45m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $190–1,100
- Website
- allegiantair.com
Flights from Newark Liberty International Airport to Des Moines
- Ave. Duration
- 3h 5m
- When
- Friday
- Estimated price
- $160–850
Flights from Philadelphia International Airport to Des Moines
- Ave. Duration
- 2h 44m
- When
- Thursday
- Estimated price
- $190–1,000
- Website
- southwest.com
Flights from Laguardia Airport to Des Moines via Chicago Midway
- Ave. Duration
- 5h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $190–1,000
Flights from Laguardia Airport to Des Moines via St. Louis
- Ave. Duration
- 5h 20m
- When
- Sunday
- Estimated price
- $200–1,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Chicago Union Station
- Ave. Duration
- 19h 32m
- Frequency
- Once daily
- Estimated price
- $120–450
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $18–250
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 33m
- Frequency
- Hourly
- Estimated price
- $12–230
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $12–230
- Business Class
- $60–270
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 10m
- Frequency
- Every 2 hours
- Estimated price
- $20–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $20–460
- First Class
- $130–600
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from New York Midtown to Chicago Bus Station
- Ave. Duration
- 20h 25m
- Frequency
- Once daily
- Estimated price
- $90–220
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $40–110
- Website
- https://www.greyhound.com/
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More Questions & Answers
Yes, the driving distance between Manhattan to Des Moines is 1114 miles. It takes approximately 18h 28m to drive from Manhattan to Des Moines.
Book your Manhattan to Des Moines bus tickets online with Omio and FlixBus.
There are 245+ hotels available in Des Moines.







