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How to get fromManhattan to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus or car

Find Transport to Des Moines

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There are 6 ways to get from Manhattan to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Newark Liberty International Airport

    best
    1. Fly from Newark Liberty International Airport (EWR) to Des Moines (DSM)plane plane EWR - DSM
    4h 47m
    $197–898
  2. Bus

    cheapest
    1. Take the bus from New York Midtown to Chicago Bus Stationbus bus FlixBus N2640
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    27h 59m
    $132–327
  3. Train, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    28h 47m
    $163–567
  4. Drive 1,107.8 mi

    1. Drive from Manhattan to Des Moinescar car 1,107.8 mi
    18h 28m
    $203–292
  5. Fly from Laguardia Airport

    1. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    5h
    $210–1,028
  6. Train to Philadelphia International Airport, fly

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    6h 8m
    $220–1,617

Manhattan to Des Moines by bus

Calendar7Weekly Buses
Duration27h 59mAverage Duration
Ticket$132Cheapest Price
See schedules

Questions & Answers

What companies run services between Manhattan, NY, USA and Des Moines, IA, USA?

Allegiant Air, Delta, and two other airlines fly from Newark Liberty International Airport (EWR) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from New York Midtown to Des Moines via Chicago Bus Station in around 27h 59m.

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