There are 6 ways to get from Manhattan to St. Louis by shuttle, bus, taxi, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Shuttle, bus  •  7 h 28 min

  1. Take a shuttle bus from Manhattan, KS to Topeka, KS
  2. Take the bus from Topeka, Ks to Kansas City, Mo
  3. Take the bus from Kansas City, Mo to St Louis, Mo

$87 - $147

5 alternative options

Taxi, train  •  9 h 42 min

  1. Take a taxi from Manhattan to Topeka Amtrak
  2. Take the train from Topeka Amtrak to Kansas City Amtrak
  3. Take the train from Kansas City Amtrak to St. Louis Gateway Station Amtrak

$215 - $350

Drive  •  6 h 4 min

  1. Drive from Manhattan to St. Louis 370 miles

$35 - $55

Fly from Manhattan  •  4 h 53 min

  1. Fly from Manhattan (MHK) to St. Louis (STL) MHK - STL

$311 - $1,336

Fly from Kansas City  •  5 h 20 min

  1. Fly from Kansas City (MCI) to St. Louis (STL) MCI - STL

$236 - $424

Drive to Wichita, fly  •  4 h 16 min

  1. Drive from Manhattan to Wichita
  2. Fly from Wichita (ICT) to St. Louis (STL) ICT - STL

$235 - $1,021

What companies run services between Manhattan, KS, USA and St. Louis, MO, USA?

American Airlines flies from Manhattan to St. Louis every 3 hours.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Kansas City to St. Louis
Ave. Duration
58 min
When
Every day
Estimated price
$130 - $420
Flights from Wichita to St. Louis
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$220 - $1,000
American Airlines
Website
aa.com
Flights from Manhattan to St. Louis via Chicago O'Hare
Ave. Duration
4 h 56 min
When
Every day
Estimated price
$280 - $1,300
Flights from Manhattan to St. Louis via Dallas/Ft.Worth
Ave. Duration
4 h 58 min
When
Every day
Estimated price
$310 - $1,400
Flights from Manhattan to St. Louis via Dallas/Ft.Worth, Chicago O'Hare
Ave. Duration
8 h 43 min
When
Saturday
Estimated price
$360 - $1,500
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Topeka Amtrak to Kansas City Amtrak
Ave. Duration
2 h 6 min
Frequency
Twice daily
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $55
Room
$140 - $200
Train from Kansas City Amtrak to St. Louis Gateway Station Amtrak
Ave. Duration
5 h 40 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
KCI RoadRunner
Website
kciroadrunner.com
Shuttle from Manhattan, KS to Topeka, KS
Ave. Duration
1 h 5 min
Frequency
Every 4 hours
Estimated price
$46 - $50
Schedules at
arivalshuttle.com
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Topeka, Ks to Kansas City, Mo
Ave. Duration
1 h 10 min
Frequency
Hourly
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $19
Flexible
$22 - $28
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Other operators
Taxi from Manhattan to Topeka Amtrak
Ave. Duration
56 min
Estimated price
$130 - $170

Want to know more about travelling around United States

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Questions & Answers

The distance between Manhattan and St. Louis is 555 km. The road distance is 592 km.

The cheapest way to get from Manhattan to St. Louis is to drive which costs $35 - $55 and takes 6 h 4 min.

The quickest way to get from Manhattan to St. Louis is to drive and fly which takes 4 h 16 min and costs $230 - $1,100.

It takes approximately 7 h 28 min to get from Manhattan to St. Louis, including transfers.