There are 5 ways to get from Manhattan to St. Louis by shuttle, bus, taxi, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Shuttle, bus  •  7 h 32 min

  1. Take a shuttle bus from Manhattan, KS to Topeka, KS
  2. Take the bus from Topeka, Ks to Kansas City, Mo
  3. Take the bus from Kansas City, Mo to St Louis, Mo

$88 - $148

4 alternative options

Taxi, train  •  9 h 49 min

  1. Take a taxi from Manhattan to Topeka Amtrak
  2. Take the train from Topeka Amtrak to Kansas City Amtrak
  3. Take the train from Kansas City Amtrak to St. Louis Gateway Station

$215 - $350

Drive  •  6 h 4 min

  1. Drive from Manhattan to St. Louis 370 miles

$35 - $55

Fly from Manhattan  •  4 h 56 min

  1. Fly from Manhattan (MHK) to St. Louis (STL) MHK - STL

$312 - $1,337

Shuttle to Kansas City, fly  •  5 h 21 min

  1. Take a shuttle bus from Manhattan, KS to Kansas City International Airport, MO
  2. Fly from Kansas City (MCI) to St. Louis (STL) MCI - STL

$237 - $425

Questions & Answers

The distance between Manhattan and St. Louis is 347 miles. The road distance is 370 miles.

Get driving directions

The best way to get from Manhattan to St. Louis without a car is to shuttle and bus which takes 7 h 32 min and costs .

More details

It takes approximately 7 h 32 min to get from Manhattan to St. Louis, including transfers.

More details

There is no direct flight from Manhattan Airport to St. Louis Airport. The quickest flight takes 4 h 4 min and has one stopover.

Search flights

Yes, the driving distance between Manhattan to St. Louis is 370 miles. It takes approximately 6 h 4 min to drive from Manhattan to St. Louis.

Get driving directions

American Airlines offers flights from Manhattan Airport to St. Louis Airport.

Search flights

There are 193+ hotels available in St. Louis. Prices start at $70 USD per night.

More details

The best way to get from Manhattan to Manhattan Airport is to taxi which takes 11 min and costs .

More details

Map of how to get from Manhattan to St. Louis.
Launch map view
  • Distance: 346.8 miles
  • Duration: 7 h 32 min

What companies run services between Manhattan, KS, USA and St. Louis, MO, USA?

American Airlines flies from Manhattan to St. Louis every 2 hours.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Kansas City to St. Louis
Ave. Duration
55 min
When
Every day
Estimated price
$130 - $420
American Airlines
Website
aa.com
Flights from Manhattan to St. Louis via Chicago O'Hare
Ave. Duration
4 h 46 min
When
Every day
Estimated price
$280 - $1,300
Flights from Manhattan to St. Louis via Dallas/Ft.Worth
Ave. Duration
5 h 11 min
When
Every day
Estimated price
$310 - $1,400
Flights from Manhattan to St. Louis via Dallas/Ft.Worth, Chicago O'Hare
Ave. Duration
8 h 39 min
When
Every day
Estimated price
$360 - $1,500
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Topeka Amtrak to Kansas City Amtrak
Ave. Duration
2 h 13 min
Frequency
Twice daily
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $55
Room
$140 - $200
Train from Kansas City Amtrak to St. Louis Gateway Station
Ave. Duration
5 h 40 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
KCI RoadRunner
Website
kciroadrunner.com
Shuttle from Manhattan, KS to Topeka, KS
Ave. Duration
1 h 5 min
Frequency
Every 4 hours
Estimated price
$46 - $50
Schedules at
arivalshuttle.com
Shuttle from Manhattan, KS to Kansas City International Airport, MO
Ave. Duration
2 h 45 min
Frequency
Every 4 hours
Estimated price
$100 - $115
Schedules at
arivalshuttle.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Topeka, Ks to Kansas City, Mo
Ave. Duration
1 h 30 min
Frequency
Hourly
Estimated price
$13 - $29
Website
greyhound.com
Economy
$13 - $19
Flexible
$23 - $29
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Other operators
Taxi from Manhattan to Topeka Amtrak
Ave. Duration
56 min
Estimated price
$130 - $170

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