There are 9 ways to get from Manduria to Siena by bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Manduria to Taranto Porto Mercantilebus
- Take the train from Taranto to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
10h 13m€118–220Bus
cheapest- Take the bus from Manduria to Lecce Via V. Carlucciobus Linea 97 Corsa 0541
- Take the bus from Lecce Central Bus Station to Siena Central Train Stationbus Itabus
13h 10m€48–100Bus via Rome
- Take the bus from Manduria to Roma, Autostazione Tiburtinabus N555
- Take the bus from Roma, Autostazione Tiburtina to Sienabus 1520
12h 30m€66–107Drive 757.9 km
- Drive from Manduria to Sienacar 757.9 km
8h€121–174Fly Brindisi Airport to Pisa International Airport, train
- Fly from Brindisi Airport (BDS) to Pisa International Airport (PSA)plane BDS - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 25m€68–279Fly Brindisi Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Brindisi Airport (BDS) to Bologna Guglielmo Marconi Airport (BLQ)plane BDS - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 14m€66–264Fly Brindisi Airport to Fiumicino International Airport, train
- Fly from Brindisi Airport (BDS) to Fiumicino International Airport (FCO)plane BDS - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 29m€78–295Bus, bus to Bari Karol Wojtyła Airport, fly to Pisa International Airport, train
- Take the bus from Manduria to Gioia Del Collebus
- Take the bus from Gioia del Colle - Ospedale to Altamura - Alberghierobus
- Take the bus from Altamura Via Matera to Bari Airportbus
- Fly from Bari Karol Wojtyła Airport (BRI) to Pisa International Airport (PSA)plane BRI - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
10h 23m€65–251Fly Brindisi Airport to Venice Marco Polo Airport, train
- Fly from Brindisi Airport (BDS) to Venice Marco Polo Airport (VCE)plane BDS - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
10h 27m€89–286
Manduria to Siena by bus
Questions & Answers
The cheapest way to get from Manduria to Siena is to bus which costs €45 - €100 and takes 13h 10m.
The fastest way to get from Manduria to Siena is to fly and train which takes 7h 25m and costs €65 - €280.
No, there is no direct bus from Manduria to Siena. However, there are services departing from Manduria and arriving at Siena via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 12h 30m.
The distance between Manduria and Siena is 896 km. The road distance is 757.9 km.
The best way to get from Manduria to Siena without a car is to bus and train which takes 10h 13m and costs €110 - €220.
It takes approximately 10h 13m to get from Manduria to Siena, including transfers.
Manduria to Siena bus services, operated by FlixBus, depart from Manduria station.
Manduria to Siena bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Yes, the driving distance between Manduria to Siena is 758 km. It takes approximately 8h to drive from Manduria to Siena.
Book your Manduria to Siena bus tickets online with Omio and FlixBus.
What companies run services between Manduria, Italy and Siena, Italy?
You can take a bus from Manduria to Siena via Roma, Autostazione Tiburtina in around 12h 30m.
- Website
- ryanair.com
Flights from Brindisi Airport to Pisa International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €45–230
Flights from Brindisi Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €35–190
Flights from Brindisi Airport to Fiumicino International Airport
- Ave. Duration
- 1h 20m
- When
- Saturday to Wednesday
- Estimated price
- €29–180
Flights from Bari Karol Wojtyła Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–190
Flights from Bari Karol Wojtyła Airport to Pisa International Airport via Palermo
- Ave. Duration
- 3h 30m
- When
- Saturday
- Estimated price
- €35–190
Flights from Brindisi Airport to Venice Marco Polo Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Sunday, and Saturday
- Estimated price
- €30–160
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Taranto to Firenze S.M.N.
- Ave. Duration
- 6h 36m
- Frequency
- Once daily
- Estimated price
- €110–210
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–25
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €35–70
- Website
- Trenitalia Frecce
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- 0832-228441
- info@stplecce.it
- Website
- stplecce.it
Bus from Manduria to Taranto Porto Mercantile
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- €2–5
- Schedules at
- stplecce.it
- 2nd Class
- €3–5
Bus from Manduria to Lecce Via V. Carluccio
- Ave. Duration
- 1h 5m
- Frequency
- 3 times a day
- Estimated price
- €3–5
- Schedules at
- stplecce.it
- 2nd Class
- €3–5
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
There are 2503+ hotels available in Siena.










