Rome2Rio

How to get fromManduria to Sienaby bus, train, car, plane, or train (Trenitalia)

Find Transport to Siena

See all options

There are 13 ways to get from Manduria to Siena by bus, train, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train via Naples

    best
    1. Take the bus from Manduria to Taranto Porto Mercantilebus bus
    2. Take the train from Taranto to Napoli Centraletrain train Ic
    3. Take the train from Napoli Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 28m
    €99–233
  2. Train, train to Brindisi Airport, fly to Perugia Sant'Egidio Airport, bus

    cheapest
    1. Take the train from Manduria to Francavilla Fontanatrain train
    2. Take the train from Francavilla Fontana to Brindisitrain train
    3. Fly from Brindisi Airport (BDS) to Perugia Sant'Egidio Airport (PEG)plane plane BDS - PEG
    4. Take the bus from Aeroporto "San Francesco d'Assisi" to Perugia - Bus Terminalbus bus
    5. Take the bus from Perugia to Sienabus bus
    9h 51m
    €51–240
  3. Bus via Rome

    1. Take the bus from Manduria to Roma, Autostazione Tiburtinabus bus N555
    2. Take the bus from Roma, Autostazione Tiburtina to Sienabus bus 1520
    12h 30m
    €65–107
  4. Drive 757.8 km

    1. Drive from Manduria to Sienacar car 757.8 km
    8h
    €121–174
  5. Fly Brindisi Airport to Pisa International Airport, train

    1. Fly from Brindisi Airport (BDS) to Pisa International Airport (PSA)plane plane BDS - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    8h 3m
    €63–222
  6. Train (Trenitalia)

    1. Take the train from Brindisi to Roma Terminitrain train Fa / ...
    2. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    12h 2m
    €128–275
  7. Bus, train

    1. Take the bus from Manduria to Taranto Porto Mercantilebus bus
    2. Take the train from Taranto to Roma Terminitrain train Ic
    3. Take the train from Roma Termini to Chiusi-Chianciano T.train train
    4. Take the train from Chiusi-Chianciano T. to Sienatrain train Re
    12h 52m
    €84–177
  8. Bus

    1. Take the bus from Manduria to Lecce Via V. Carlucciobus bus Linea 97 Corsa 0541
    2. Take the bus from Lecce Central Bus Station to Siena Central Train Stationbus bus Itabus
    13h 10m
    €53–105
  9. Fly Brindisi Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Brindisi Airport (BDS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane BDS - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 38m
    €71–198
  10. Bus, bus to Bari Karol Wojtyła Airport, fly to Pisa International Airport, train

    1. Take the bus from Manduria to Gioia Del Collebus bus
    2. Take the bus from Gioia del Colle - Ospedale to Altamura - Alberghierobus bus
    3. Take the bus from Altamura Via Matera to Bari Airportbus bus
    4. Fly from Bari Karol Wojtyła Airport (BRI) to Pisa International Airport (PSA)plane plane BRI - PSA
    5. Take the train from Pisa Centrale to Empolitrain train
    6. Take the train from Empoli to Sienatrain train
    10h 2m
    €65–193
  11. Bus, bus to Bari Karol Wojtyła Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the bus from Manduria to Gioia Del Collebus bus
    2. Take the bus from Gioia del Colle - Ospedale to Altamura - Alberghierobus bus
    3. Take the bus from Altamura Via Matera to Bari Airportbus bus
    4. Fly from Bari Karol Wojtyła Airport (BRI) to Bologna Guglielmo Marconi Airport (BLQ)plane plane BRI - BLQ
    5. Take the train from Bologna Centrale to Firenze S.M.N.train train
    6. Take the train from Firenze S.M.N. to Sienatrain train
    10h 38m
    €68–199
  12. Fly Brindisi Airport to Fiumicino International Airport, train

    1. Fly from Brindisi Airport (BDS) to Fiumicino International Airport (FCO)plane plane BDS - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 54m
    €77–273
  13. Fly Brindisi Airport to Venice Marco Polo Airport, train

    1. Fly from Brindisi Airport (BDS) to Venice Marco Polo Airport (VCE)plane plane BDS - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    10h 40m
    €83–253

Manduria to Siena by bus

Calendar7Weekly Buses
Duration12h 30mAverage Duration
Ticket€65Cheapest Price
See schedules

Questions & Answers

What companies run services between Manduria, Italy and Siena, Italy?

You can take a bus from Manduria to Siena via Roma, Autostazione Tiburtina in around 12h 30m. Alternatively, you can take a train from Manduria to Siena via Francavilla Fontana, Brindisi, Roma Termini, and Firenze S.M.N. in around 12h 2m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers