There are 10 ways to get from Mainz to Zürich by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  4 h 18 min

  1. Ec

$100 - $160

Cheapest option

Bus via Frankfurt  •  7 h 20 min

  1. X07 / ...

$25 - $43

8 alternative options

Train via Basel SBB  •  4 h 41 min

  1. Re / ...
  2. Ice / ...
  3. 3 / ...

$102 - $176

Train via Mannheim Hbf  •  5 h 32 min

  1. Rb / ...
  2. Ice / ...

$97 - $160

Train, bus  •  7 h 48 min

  1. Rb / ...
  2. Ouibus

$35 - $51

Bus  •  9 h 10 min

  1. N207 / ...

$29 - $50

Drive  •  3 h 43 min

  1. 256.5 miles

$50 - $80

Fly Frankfurt to Zurich  •  2 h 50 min

  1. FRA - ZRH

$109 - $300

Fly Frankfurt to Basel, train  •  3 h 45 min

  1. FRA - BSL

$116 - $354

Bus to Luxembourg, fly to Zurich  •  5 h 35 min

  1. LUX - ZRH

$86 - $294

What companies run services between Mainz, Germany and Zürich, Switzerland?

Deutsche Bahn operates a train from Mainz to Zürich once daily. Tickets cost $100 - $160 and the journey takes 4 h 18 min. Alternatively, FlixBus operates a bus from Mainz to Zürich 4 times a day. Tickets cost $23 - $40 and the journey takes 5 h 15 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Zurich
Ave. Duration
55 min
When
Every day
Estimated price
$150 - $650
Flights from Frankfurt to Zurich via Stuttgart
Ave. Duration
2 h 32 min
When
Every day
Estimated price
$140 - $650
Flights from Frankfurt to Zurich via Nuremberg
Ave. Duration
2 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$150 - $650
Flights from Frankfurt to Basel
Ave. Duration
45 min
When
Every day
Estimated price
$110 - $380
Flights from Luxembourg to Zurich via Frankfurt
Ave. Duration
2 h 50 min
When
Every day
Estimated price
$170 - $700
Swiss
Website
swiss.com
Flights from Frankfurt to Zurich
Ave. Duration
55 min
When
Every day
Estimated price
$150 - $650
Flights from Frankfurt to Basel
Ave. Duration
45 min
When
Every day
Estimated price
$110 - $380
Flights from Luxembourg to Zurich
Ave. Duration
56 min
When
Every day
Estimated price
$110 - $900
Train operators
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Mainz Hbf to Zürich HB
Ave. Duration
4 h 18 min
Frequency
Once daily
Estimated price
$100 - $160
Website
bahn.de
Train from Mainz Hbf to Mannheim Hbf
Ave. Duration
50 min
Frequency
Hourly
Estimated price
$21 - $35
Website
bahn.de
Train from Mannheim Hbf to Basel SBB
Ave. Duration
2 h 11 min
Frequency
Hourly
Estimated price
$50 - $85
Website
bahn.de
Train from Mainz Römisches Theater to Mannheim Hbf
Ave. Duration
1 h 17 min
Frequency
Every 30 minutes
Estimated price
$21 - $35
Website
bahn.de
Train from Mannheim Hbf to Zürich HB
Ave. Duration
3 h 15 min
Frequency
Every 4 hours
Estimated price
$75 - $130
Website
bahn.de
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Basel SBB to Zürich HB
Ave. Duration
53 min
Frequency
Hourly
Estimated price
$30 - $60
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Frankfurt, Frankfurt central station to Zurich
Ave. Duration
5 h 15 min
Frequency
4 times a day
Estimated price
$23 - $40
Website
flixbus.co.uk
Bus from Mainz to Zurich
Ave. Duration
9 h 10 min
Frequency
Twice daily
Estimated price
$29 - $50
Website
flixbus.co.uk
Ouibus
Phone
0890715298
Website
ouibus.com
Bus from Mannheim to Winterthur
Ave. Duration
5 h 35 min
Frequency
Every 15 minutes
Estimated price
$12 - $18
Website
Ouibus
Bus from Mainz to Luxembourg
Ave. Duration
2 h 25 min
Frequency
Hourly
Estimated price
$7 - $11
Website
Ouibus

Want to know more about travelling around Switzerland

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Mainz and Zürich is 292 km. The road distance is 410 km.

The cheapest way to get from Mainz to Zürich is to bus which costs 21€ - 40€ and takes 7 h 20 min.

The quickest way to get from Mainz to Zürich is to fly which takes 2 h 50 min and costs 90€ - 260€.

Yes, there is a direct train departing from Mainz Hbf and arriving at Zürich HB. Services depart once daily. The journey takes approximately 4 h 18 min.

Yes, there is a direct bus departing from Mainz and arriving at Zurich. Services depart twice daily, and operate every day. The journey takes approximately 9 h 10 min.

The train from Mainz Hbf to Zürich HB takes 4 h 18 min including transfers and departs once daily.