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How to get fromMainz to Sicilyby plane, car, car ferry, train, night train or bus

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There are 10 ways to get from Mainz to Sicily by plane, car, car ferry, train, night train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Catania–Fontanarossa Airport

    best
    1. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)planeFRA - CTA
    5h 11m
    €98–266

  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Milano, Autostazione Lampugnanobus476
    2. Take the bus from Milano, Autostazione Lampugnano to PalermobusN597
    35h 43m
    €94–253

  3. Drive, car ferry

    1. Drive from Mainz to Port of Genoacar
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry
    28h 33m
    €184–309

  4. Train, night train

    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain22 / ...
    3. Take the night train from Stuttgart Hbf to Venezia MestrenighttrainNj
    4. Take the train from Venezia Mestre to Roma TerminitrainFr
    5. Take the train from Roma Termini to Palermo CentraletrainIc
    32h 22m
    €153–564

  5. Fly Frankfurt to Palermo Airport

    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)planeFRA - PMO
    5h 39m
    €95–238

  6. Bus to Hahn, fly to Catania–Fontanarossa Airport

    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
    2. Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)planeHHN - CTA
    6h 17m
    €108–294

  7. Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
    2. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)planeSTR - CTA
    6h 54m
    €106–345

  8. Train to Cologne Bonn Airport, fly to Palermo Airport

    1. Take the train from Frankfurt to Siegburg Bftrain
    2. Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)planeCGN - PMO
    7h 26m
    €110–395

  9. Train, car ferry

    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain20 / ...
    3. Take the train from Basel SBB to Zürich HBtrainIce / ...
    4. Take the train from Zürich HB to Genova P. PrincipetrainEc
    5. Take the car ferry from Port of Genoa to Port of Palermocarferry
    35h 39m
    €257–587

  10. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS5 / ...
    2. Take the bus from Mannheim Central Bus Station to Milanbus
    3. Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus
    36h 53m
    €106–162

Mainz to Sicily by train and night train

Calendar7Weekly Services
Duration32h 22mAverage Duration
Ticket€153Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Sicily, Italy?

Lufthansa, Air Dolomiti, and three other airlines fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) 3 times a day. Alternatively, you can take a bus from Mainz central train station to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 35h 43m.

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