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How to get fromMainz to Sicilyby plane, car, car ferry, train, night train, or bus

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There are 11 ways to get from Mainz to Sicily by plane, car, car ferry, train, night train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Catania–Fontanarossa Airport

    best
    1. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    5h 16m
    €89–236

  2. Bus to Hahn, fly to Palermo Airport

    cheapest
    1. Take the bus from Mainz, Hauptbahnhof to Hahnbus bus
    2. Fly from Hahn (HHN) to Palermo Airport (PMO)plane plane HHN - PMO
    6h 23m
    €72–253

  3. Drive, car ferry

    1. Drive from Mainz to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    28h 34m
    €222–333

  4. Train, night train

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train 11 / ...
    3. Take the night train from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    4. Take the train from Verona Porta Nuova to Roma Terminitrain train Fr
    5. Take the train from Roma Termini to Palermo Centraletrain train Ic
    32h 37m
    €226–594

  5. Bus

    1. Take the bus from Mühlheim am Main to Palermo Piazza Cairolibus bus
    32h 53m

  6. Fly Frankfurt to Palermo Airport

    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    5h 37m
    €83–219

  7. Bus to Hahn, fly to Catania–Fontanarossa Airport

    1. Take the bus from Mainz, Hauptbahnhof to Hahnbus bus
    2. Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane plane HHN - CTA
    6h 2m
    €98–230

  8. Train, train to Stuttgart Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    3. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane plane STR - CTA
    6h 46m
    €102–352

  9. Train to Cologne Bonn Airport, fly to Palermo Airport

    1. Take the train from Frankfurt to Siegburg Bftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane plane CGN - PMO
    7h 27m
    €91–421

  10. Bus via Milan

    1. Take the bus from Mainz central train station to Milanbus bus FlixBus 476
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    35h 33m
    €194–323

  11. Bus #2

    1. Take the bus from Wiesbaden Gartenfeldstraße P+R to Palermo Piazza Cairolibus bus
    38h 41m

Mainz to Sicily by train and night train

Calendar14Weekly Services
Duration32h 37mAverage Duration
Ticket€226Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Sicily.ExpandLaunch map view
  • Distance: 1,521.8 km
  • Duration: 5h 16m

What companies run services between Mainz, Germany and Sicily, Italy?

Lufthansa, Lufthansa City, and two other airlines fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) 5 times a day. Alternatively, Onebus operates a bus from Mühlheim am Main to Palermo Piazza Cairoli once a week, and the journey takes 28h 19m.

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