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How to get fromMainz to Sicilyby plane, car, car ferry, train, night train, or bus

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There are 11 ways to get from Mainz to Sicily by plane, car, car ferry, train, night train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Catania–Fontanarossa Airport

    best
    1. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    5h 15m
    €89–246

  2. Bus to Hahn, fly to Palermo Airport

    cheapest
    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus bus
    2. Fly from Hahn (HHN) to Palermo Airport (PMO)plane plane HHN - PMO
    6h 23m
    €76–262

  3. Drive, car ferry

    1. Drive from Mainz to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    28h 34m
    €223–334

  4. Train, night train

    1. Take the train from Frankfurt to Hauptbahnhoftrain train 47 / ...
    2. Take the night train from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    33h 15m
    €225–604

  5. Bus

    1. Take the bus from Mainz central train station to Milanbus bus FlixBus 476
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    35h 31m
    €118–294

  6. Fly Frankfurt to Palermo Airport

    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    5h 36m
    €88–269

  7. Bus to Hahn, fly to Catania–Fontanarossa Airport

    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus bus
    2. Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane plane HHN - CTA
    6h 2m
    €102–229

  8. Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Frankfurt to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane plane STR - CTA
    7h 19m
    €106–352

  9. Train to Cologne Bonn Airport, fly to Palermo Airport

    1. Take the train from Frankfurt to Siegburg Bftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane plane CGN - PMO
    7h 33m
    €87–349

  10. Train, car ferry

    1. Take the train from Frankfurt to Chiassotrain train Ec
    2. Take the train from Chiasso to Genova P. Principetrain train Ec
    3. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    35h
    €404–1,076

  11. Train, bus

    1. Take the train from Mainz, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train 55 / ...
    2. Take the bus from Karlsruhe central train station to Strasbourgbus bus 321 / ...
    3. Take the bus from Strasbourg - L'Étoile Park Bus Station to Milano, Autostazione Lampugnanobus bus
    4. Take the bus from Milano, Autostazione Lampugnano to Alcamo SP55bus bus
    5. Take the bus from Alcamo via Gulliver to PALERMO via Sciuti Liberta'bus bus
    38h 21m
    €131–277

Mainz to Sicily by train and night train

Calendar14Weekly Services
Duration33h 15mAverage Duration
Ticket€225Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Sicily.ExpandLaunch map view
  • Distance: 1,521.8 km
  • Duration: 5h 15m

What companies run services between Mainz, Germany and Sicily, Italy?

Lufthansa, Lufthansa City, and two other airlines fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) 5 times a day. Alternatively, you can take a bus from Mainz central train station to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 35h 31m.

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