There are 11 ways to get from Mainz to Sicily by plane, car, car ferry, train, night train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Catania–Fontanarossa Airport
best- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
5h 16m€75–306Bus to Hahn, fly to Palermo Airport
cheapest- Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
- Fly from Hahn (HHN) to Palermo Airport (PMO)plane HHN - PMO
6h 32m€71–252Drive, car ferry
- Drive from Mainz to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
28h 34m€216–321Train, night train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain 55 / ...
- Take the night train from Stuttgart Hbf to Verona Porta Nuovanighttrain Nj
- Take the train from Verona Porta Nuova to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
32h 46m€229–529Bus
- Take the bus from Mainz central train station to Milanbus FlixBus 476
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
35h 29m€115–280Fly Frankfurt to Palermo Airport
- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
5h 46m€94–269Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane STR - CTA
6h 50m€106–307Bus to Hahn, fly to Catania–Fontanarossa Airport
- Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
- Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane HHN - CTA
6h 2m€132–299Train to Cologne Bonn Airport, fly to Palermo Airport
- Take the train from Frankfurt to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane CGN - PMO
7h 27m€95–356Train, car ferry
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Genova P. Principetrain Ec
- Take the car ferry from Port of Genoa to Port of Palermocarferry
34h 59m€385–1,006Train, bus
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
- Take the bus from Basel to Milano, Autostazione Lampugnanobus
- Take the bus from Milano, Autostazione Lampugnano to Alcamo SP55bus
- Take the bus from Alcamo via Gulliver to PALERMO via Sciuti Liberta'bus
36h 12m€138–288
Mainz to Sicily by bus
Questions & Answers
The cheapest way to get from Mainz to Sicily is to bus and fly which costs €70 - €260 and takes 6h 32m.
The fastest way to get from Mainz to Sicily is to fly which takes 5h 16m and costs €70 - €310.
No, there is no direct bus from Mainz station to Sicily. However, there are services departing from Mainz central train station and arriving at Piazza Boiardo via Milano, Autostazione Lampugnano and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 35h 29m.
No, there is no direct train from Mainz to Sicily. However, there are services departing from Mainz, Hauptbahnhof and arriving at Palermo Notarbartolo via Stuttgart Hbf, Verona Porta Nuova, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 32h 46m.
The distance between Mainz and Sicily is 1523 km.
The best way to get from Mainz to Sicily without a car is to train and night train which takes 32h 46m and costs €220 - €550.
It takes approximately 5h 16m to get from Mainz to Sicily, including transfers.
Mainz to Sicily bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Sicily train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Sicily is to fly which takes 5h 16m and costs €70 - €310. Alternatively, you can bus, which costs €110 - €280 and takes 35h 29m.
What companies run services between Mainz, Germany and Sicily, Italy?
Lufthansa, ITA Airways, and Lufthansa City fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) 5 times a day. Alternatively, you can take a bus from Mainz central train station to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 35h 29m.
- Website
- lufthansa.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €100–380
Flights from Frankfurt to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €70–380
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–410
Flights from Frankfurt to Palermo Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €100–410
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- €100–400
Flights from Cologne Bonn Airport to Palermo Airport via Munich
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €100–400
- Website
- ita-airways.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €100–380
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–320
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- €85–230
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- €65–200
- Website
- eurowings.com
Flights from Stuttgart Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- €65–200
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €65–220
- Website
- ryanair.com
Flights from Hahn to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €50–210
Flights from Hahn to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Tuesday, Friday, and Saturday
- Estimated price
- €50–200
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 25m
- When
- Wednesday and Saturday
- Estimated price
- €65–250
- Website
- swiss.com
Flights from Frankfurt to Palermo Airport via Zurich
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- €100–380
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 37m
- Frequency
- Every 3 hours
- Estimated price
- €30–80
- Website
- https://int.bahn.de/en
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- €26–65
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- €45–110
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Stuttgart Hbf to Verona Porta Nuova
- Ave. Duration
- 12h 32m
- Frequency
- Once daily
- Estimated price
- €45–130
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €100–130
- Couchette Carriage
- €75–90
- Seating Carriage
- €45–60
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Verona Porta Nuova to Roma Termini
- Ave. Duration
- 3h 18m
- Frequency
- Every 3 hours
- Estimated price
- €60–120
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €90–200
- Website
- https://www.trenitalia.com/en.html
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 39 min
- Frequency
- Every 4 hours
- Estimated price
- €15–35
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €27–65
- Website
- https://www.ns.nl/en
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 40 min
- Frequency
- 5 times a week
- Estimated price
- €27–55
- Website
- https://www.belgiantrain.be/en
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €220–650
- Website
- https://www.sbb.ch/en
Train from Chiasso to Genova P. Principe
- Ave. Duration
- 2h 50m
- Frequency
- Twice a week
- Estimated price
- €65–200
- Website
- https://www.sbb.ch/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €14–21
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Once daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- €55–100
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Mainz central train station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- €50–90
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €110–190
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 45m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- autoservizisalemi.it
Bus from Milano, Autostazione Lampugnano to Alcamo SP55
- Ave. Duration
- 22h 45m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- autoservizisalemi.it
- info@flibco.com
- Website
- flibco.com
Bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airport
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €17–35
- Website
- https://www.flibco.com/en
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Basel to Milano, Autostazione Lampugnano
- Ave. Duration
- 5h 15m
- Frequency
- 4 times a day
- Estimated price
- €26–50
- Website
- https://www.blablacar.co.uk/bus
- Phone
- 06 164 160, +39091342525
- info@segesta.it
- Website
- segesta.it
Bus from Alcamo via Gulliver to PALERMO via Sciuti Liberta'
- Ave. Duration
- 1h 13m
- Frequency
- Hourly
- Estimated price
- €11–17
- Schedules at
- segesta.it
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €90–140
- Website
- https://www.gnv.it/en
Want to know more about travelling around Italy
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More Questions & Answers
Mainz to Sicily bus services, operated by FlixBus, arrive at Milan station.
Mainz to Sicily train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hauptbahnhof station.
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