There are 9 ways to get from Mainz to Sicily by plane, car, car ferry, train, night train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Palermo Airport
best- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
5h 46m€96–289Bus to Hahn, fly to Catania–Fontanarossa Airport
cheapest- Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
- Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane HHN - CTA
6h 9m€68–227Drive, car ferry
- Drive from Mainz to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
28h 34m€219–329Train, night train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain 55 / ...
- Take the night train from Stuttgart Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
32h 5m€231–549Bus
- Take the bus from Mainz central train station to Milanbus FlixBus 476
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
35h 31m€114–281Fly Frankfurt to Catania–Fontanarossa Airport
- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
5h 23m€88–304Bus to Hahn, fly to Palermo Airport
- Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
- Fly from Hahn (HHN) to Palermo Airport (PMO)plane HHN - PMO
6h 32m€71–252Train, bus
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the bus from Mannheim central bus station to Milano, Autostazione Lampugnanobus N77
- Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus
36h 20m€117–196Train, car ferry
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
- Take the train from Basel SBB to Como S. Giovannitrain Ec
- Take the train from Como S.Giovanni to Genova Piazza Principetrain
- Take the car ferry from Port of Genoa to Port of Palermocarferry
36h 21m€247–588
Mainz to Sicily by bus
Questions & Answers
The cheapest way to get from Mainz to Sicily is to bus and fly which costs €70 - €260 and takes 6h 32m.
The fastest way to get from Mainz to Sicily is to fly which takes 5h 23m and costs €85 - €310.
No, there is no direct bus from Mainz station to Sicily. However, there are services departing from Mainz central train station and arriving at Piazza Boiardo via Milano, Autostazione Lampugnano and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 35h 31m.
No, there is no direct train from Mainz to Sicily. However, there are services departing from Mainz, Hauptbahnhof and arriving at Palermo Notarbartolo via Stuttgart Hbf, Venezia Mestre, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 32h 5m.
The distance between Mainz and Sicily is 1425 km.
The best way to get from Mainz to Sicily without a car is to train and night train which takes 32h 5m and costs €230 - €550.
It takes approximately 5h 46m to get from Mainz to Sicily, including transfers.
Mainz to Sicily bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Sicily train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Sicily is to fly which takes 5h 46m and costs €95 - €290. Alternatively, you can bus, which costs €110 - €290 and takes 35h 31m.
What companies run services between Mainz, Germany and Sicily, Italy?
Lufthansa, ITA Airways, and Swiss fly from Frankfurt (FRA) to Palermo Airport (PMO) every 4 hours. Alternatively, you can take a bus from Mainz central train station to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 35h 31m.
- Website
- lufthansa.com
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €85–340
Flights from Frankfurt to Palermo Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €85–350
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €90–260
Flights from Frankfurt to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €90–260
- Website
- ita-airways.com
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- €80–270
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €90–260
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €85–360
- Website
- swiss.com
Flights from Frankfurt to Palermo Airport via Zurich
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- €75–310
- Website
- ryanair.com
Flights from Hahn to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €50–210
Flights from Hahn to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Tuesday, Friday, and Saturday
- Estimated price
- €50–190
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 37m
- Frequency
- Every 3 hours
- Estimated price
- €30–80
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- €45–110
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Stuttgart Hbf to Venezia Mestre
- Ave. Duration
- 11h 54m
- Frequency
- Once daily
- Estimated price
- €45–130
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €100–130
- Couchette Carriage
- €75–90
- Seating Carriage
- €45–55
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 3h 45m
- Frequency
- Hourly
- Estimated price
- €65–140
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €85–200
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €19–27
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Once daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €27–65
- Website
- https://www.ns.nl/en
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 11m
- Frequency
- 4 times a week
- Estimated price
- €55–95
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Como S. Giovanni
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €95–280
- Website
- https://www.sbb.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Como S.Giovanni to Genova Piazza Principe
- Ave. Duration
- 3h 42m
- Frequency
- Twice a week
- Estimated price
- €12–16
- Website
- https://www.trenord.it/en/
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Mainz central train station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- €50–90
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €100–190
- Website
- https://www.flixbus.co.uk
Bus from Mannheim central bus station to Milano, Autostazione Lampugnano
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- €45–80
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 45m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- autoservizisalemi.it
Bus from Milano, San Donato M3 to Palermo Via Tommaso Fazello
- Ave. Duration
- 21h
- Frequency
- Twice a week
- Estimated price
- €55–85
- Schedules at
- autoservizisalemi.it
- info@flibco.com
- Website
- flibco.com
Bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airport
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- €17–35
- Website
- https://www.flibco.com/en
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €95–150
- Website
- https://www.gnv.it/en
Want to know more about travelling around Italy
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More Questions & Answers
Mainz to Sicily bus services, operated by FlixBus, arrive at Milan station.
Mainz to Sicily train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hauptbahnhof station.
Book your Mainz to Sicily bus tickets online with Omio.
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