There are 10 ways to get from Mainz to Sicily by plane, car, car ferry, train, night train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Palermo Airport
best- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
5h 46m€100–269Bus to Hahn, fly to Palermo Airport
cheapest- Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
- Fly from Hahn (HHN) to Palermo Airport (PMO)plane HHN - PMO
6h 32m€71–252Drive, car ferry
- Drive from Mainz to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
28h 34m€219–329Train, night train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain 55 / ...
- Take the night train from Stuttgart Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
32h 3m€231–550Bus
- Take the bus from Mainz central train station to Milanbus FlixBus 476
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
35h 29m€114–280Fly Frankfurt to Catania–Fontanarossa Airport
- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
5h 23m€88–294Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane STR - CTA
6h 57m€101–328Bus to Hahn, fly to Catania–Fontanarossa Airport
- Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
- Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane HHN - CTA
6h 9m€119–587Train, car ferry
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Genova P. Principetrain Ec
- Take the car ferry from Port of Genoa to Port of Palermocarferry
34h 57m€383–960Bus via Zurich
- Take the bus from Frankfurt, Hauptbahnhof FOB to Zürich Bus Stationbus
- Take the bus from Zurigo to Milanobus
- Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus
36h 1m
Mainz to Sicily by bus
Questions & Answers
The cheapest way to get from Mainz to Sicily is to bus and fly which costs €70 - €260 and takes 6h 32m.
The fastest way to get from Mainz to Sicily is to fly which takes 5h 23m and costs €85 - €300.
No, there is no direct bus from Mainz station to Sicily. However, there are services departing from Mainz central train station and arriving at Piazza Boiardo via Milano, Autostazione Lampugnano and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 35h 29m.
No, there is no direct train from Mainz to Sicily. However, there are services departing from Mainz, Hauptbahnhof and arriving at Palermo Notarbartolo via Stuttgart Hbf, Venezia Mestre, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 32h 3m.
The distance between Mainz and Sicily is 1425 km.
The best way to get from Mainz to Sicily without a car is to train and night train which takes 32h 3m and costs €230 - €550.
It takes approximately 5h 46m to get from Mainz to Sicily, including transfers.
Mainz to Sicily bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Sicily train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Sicily is to fly which takes 5h 46m and costs €100 - €270. Alternatively, you can bus, which costs €110 - €280 and takes 35h 29m.
What companies run services between Mainz, Germany and Sicily, Italy?
Lufthansa, ITA Airways, and Swiss fly from Frankfurt (FRA) to Palermo Airport (PMO) every 4 hours. Alternatively, you can take a bus from Mainz central train station to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 35h 29m.
- Website
- lufthansa.com
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €95–370
Flights from Frankfurt to Palermo Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €95–370
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €90–270
Flights from Frankfurt to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €90–270
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- €95–380
- Website
- ita-airways.com
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- €85–230
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €90–270
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €85–320
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 16m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €60–200
- Website
- swiss.com
Flights from Frankfurt to Palermo Airport via Zurich
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- €85–340
- Website
- eurowings.com
Flights from Stuttgart Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- €60–200
- Website
- ryanair.com
Flights from Hahn to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €50–210
Flights from Hahn to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Tuesday, Friday, and Saturday
- Estimated price
- €50–550
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 37m
- Frequency
- Every 3 hours
- Estimated price
- €35–80
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Stuttgart Hbf to Venezia Mestre
- Ave. Duration
- 11h 54m
- Frequency
- Once daily
- Estimated price
- €45–130
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €100–130
- Couchette Carriage
- €75–90
- Seating Carriage
- €45–55
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 3h 45m
- Frequency
- Hourly
- Estimated price
- €65–140
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 42m
- Frequency
- Once daily
- Estimated price
- €85–200
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €210–600
- Website
- https://www.sbb.ch/en
Train from Chiasso to Genova P. Principe
- Ave. Duration
- 2h 50m
- Frequency
- Twice a week
- Estimated price
- €65–190
- Website
- https://www.sbb.ch/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Mainz central train station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- €50–90
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €110–190
- Website
- https://www.flixbus.co.uk
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 45m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- autoservizisalemi.it
Bus from Milano, San Donato M3 to Palermo Via Tommaso Fazello
- Ave. Duration
- 21h
- Frequency
- Twice a week
- Estimated price
- €55–85
- Schedules at
- autoservizisalemi.it
- info@flibco.com
- Website
- flibco.com
Bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airport
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- €17–35
- Website
- https://www.flibco.com/en
- Phone
- +38 098-888-11-08
- igoruzhanskyi@grandbus.com.ua
- Website
- grandbus.com.ua
Bus from Frankfurt, Hauptbahnhof FOB to Zürich Bus Station
- Ave. Duration
- 4h 47m
- Frequency
- Once daily
- Website
- https://www.grandbus.com.ua/en
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Zurigo to Milano
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €16–30
- Website
- https://www.itabus.it/en/home
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €95–150
- Website
- https://www.gnv.it/en
Want to know more about travelling around Italy
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More Questions & Answers
Mainz to Sicily bus services, operated by FlixBus, arrive at Milan station.
Mainz to Sicily train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hauptbahnhof station.
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