There are 8 ways to get from Mainz to Sicily by plane, car, car ferry, bus, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Catania–Fontanarossa Airport
best- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
5h 10m€88–236Fly Frankfurt to Palermo Airport
cheapest- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
5h 37m€82–237Drive, car ferry
- Drive from Mainz to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
27h 19m€245–360Bus
- Take the bus from Mühlheim am Main to Palermo Piazza Cairolibus
30h 57m€266–366Train, night train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain 55 / ...
- Take the nighttrain from Stuttgart Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
31h 32m€224–475Bus to Hahn, fly to Catania–Fontanarossa Airport
- Take the bus from Mainz, Hauptbahnhof to Hahnbus
- Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane HHN - CTA
6h 12m€88–510Bus via Milan
- Take the bus from Mainz central train station to Milanbus FlixBus 476
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
35h 27m€208–309Bus #2
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Palermo Piazza Cairolibus
38h 34m€293–404
Mainz to Sicily by train and night train
Comparing Your Travel Options
The cheapest way to get from Mainz to Sicily is to fly which costs €80 - €240 and takes 5h 37m.
The fastest way to get from Mainz to Sicily is to fly which takes 5h 10m and costs €85 - €240.
No, there is no direct bus from Mainz to Sicily. However, there are services departing from Mühlheim am Main and arriving at Piazza Boiardo via Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 30h 57m.
No, there is no direct train from Mainz to Sicily. However, there are services departing from Mainz, Hauptbahnhof and arriving at Palermo Notarbartolo via Stuttgart Hbf, Venezia Mestre, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 31h 32m.
The distance between Mainz and Sicily is 1522 km.
The best way to get from Mainz to Sicily without a car is to bus which takes 30h 57m and costs €260 - €370.
It takes approximately 5h 10m to get from Mainz to Sicily, including transfers.
Mainz to Sicily bus services, operated by Onebus, depart from Mühlheim am Main station.
Mainz to Sicily train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Sicily is to fly which takes 5h 10m and costs €85 - €240. Alternatively, you can bus, which costs €260 - €370 and takes 30h 57m.
What companies run services between Mainz, Germany and Sicily, Italy?
Lufthansa, ITA Airways, and Edelweiss Air fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) 3 times a day. Alternatively, Onebus operates a bus from Mühlheim am Main to Palermo Piazza Cairoli once a week. Tickets cost €250–350 and the journey takes 28h 19m.
- Website
- ryanair.com
Flights from Hahn to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 35m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €40–190
Flights from Hahn to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 51m
- When
- Saturday and Monday
- Estimated price
- €40–190
Flights from Hahn to Catania–Fontanarossa Airport via Pescara
- Ave. Duration
- 4h 45m
- When
- Sunday
- Estimated price
- €45–190
- Website
- ita-airways.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €70–260
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- €60–200
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 5h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €95–200
- Website
- lufthansa.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €70–260
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Thursday and Saturday
- Estimated price
- €75–280
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €28–55
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Stuttgart Hbf to Venezia Mestre
- Ave. Duration
- 11h 54m
- Frequency
- 3 times a day
- Estimated price
- €45–130
- Website
- Nightjet
- Sleeper Carriage
- €100–130
- Couchette Carriage
- €75–90
- Seating Carriage
- €45–55
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 3h 44m
- Frequency
- Hourly
- Estimated price
- €70–120
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 3h 53m
- Frequency
- Hourly
- Estimated price
- €55–95
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 6h 46m
- Frequency
- 4 times a day
- Estimated price
- €55–100
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- 4 times a day
- Estimated price
- €95–170
- Website
- Trenitalia Intercity
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Mühlheim am Main to Palermo Piazza Cairoli
- Ave. Duration
- 28h 19m
- Frequency
- Once a week
- Estimated price
- €250–350
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Palermo Piazza Cairoli
- Ave. Duration
- 36h 46m
- Frequency
- Once a week
- Estimated price
- €290–400
- Website
- Onebus
- Phone
- +49 (0) 6543 5019-400
- reisebuero@bohr.de
- Website
- Bohr
Bus from Mainz, Hauptbahnhof to Hahn
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- €14–16
- Schedules at
- Bohr
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Mainz central train station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- €65–100
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €140–210
- Website
- Flixbus
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
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Booking & Getting There
Mainz to Sicily bus services, operated by Onebus, arrive at Palermo Piazza Cairoli station.
Mainz to Sicily train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hauptbahnhof station.
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