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How to get fromMainz to Sicilyby plane, car, car ferry, train, night train or bus

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There are 9 ways to get from Mainz to Sicily by plane, car, car ferry, train, night train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Catania–Fontanarossa Airport

    best
    1. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    5h 11m
    €93–316
  2. Bus to Hahn, fly to Catania–Fontanarossa Airport

    cheapest
    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus bus
    2. Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane plane HHN - CTA
    6h 17m
    €73–244
  3. Drive, car ferry

    1. Drive from Mainz to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    28h 34m
    €185–320
  4. Train, night train

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train 11 / ...
    2. Take the night train from Stuttgart Hbf to Venezia Mestrenighttrain night train Nj
    3. Take the train from Venezia Mestre to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    31h 55m
    €156–559
  5. Bus

    1. Take the bus from Mainz central train station to Milano, Autostazione Lampugnanobus bus 476
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    35h 32m
    €91–277
  6. Fly Frankfurt to Palermo Airport

    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    5h 41m
    €100–288
  7. Bus to Hahn, fly to Palermo Airport

    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus bus
    2. Fly from Hahn (HHN) to Palermo Airport (PMO)plane plane HHN - PMO
    6h 37m
    €110–316
  8. Train, car ferry

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 20 / ...
    3. Take the train from Basel SBB to Zürich HBtrain train Ice / ...
    4. Take the train from Zürich HB to Genova P. Principetrain train Ec
    5. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    35h 41m
    €257–597
  9. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the bus from Mannheim Central Bus Station to Milanbus bus
    3. Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus bus
    36h 56m
    €106–167

Mainz to Sicily by train and night train

Calendar7Weekly Services
Duration31h 55mAverage Duration
Ticket€156Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Sicily, Italy?

Lufthansa, Air Dolomiti, and ITA Airways fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) 4 times a day. Alternatively, you can take a bus from Mainz central train station to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 35h 32m.

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