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How to get fromMainz to Luganoby train, bus, car, or plane

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There are 10 ways to get from Mainz to Lugano by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    7h 12m
    CHF 51–462

  2. Bus

    cheapest
    1. Take the bus from Frankfurt central train station to Luganobus bus FlixBus N474
    10h 40m
    CHF 43–79

  3. Drive 587.6 km

    1. Drive from Mainz to Luganocar car 587.6 km
    5h 26m
    CHF 97–140

  4. Fly to Zurich Airport, train

    1. Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane plane FRA - ZRH
    2. Take the train from Zürich HB to Luganotrain train
    4h 51m
    CHF 153–423

  5. Train via Zurich

    1. Take the train from Mainz Hbf to Zürich HBtrain train Nightjet
    2. Take the train from Zürich HB to Luganotrain train Ec / ...
    8h 46m
    CHF 107–281

  6. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim Hbf to Zuerich Hbtrain train Ec
    3. Take the bus from Zurich Central Bus Station Sihlquai to Lugano Via Giacomo and Filippo Cianibus bus
    11h 14m
    CHF 92–160

  7. Fly to Milano Malpensa Airport, train

    1. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    2. Take the train from Malpensa Aeroporto T1 to Luganotrain train
    5h 38m
    CHF 75–199

  8. Fly to Milan Linate Airport, train

    1. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    2. Take the train from Monza to Luganotrain train
    5h 48m
    CHF 46–182

  9. Fly to Basel, train

    1. Fly from Frankfurt (FRA) to Basel (BSL)plane plane FRA - BSL
    2. Take the train from Basel SBB to Luganotrain train
    6h 35m
    CHF 136–577

  10. Fly to Turin Caselle Airport, train

    1. Fly from Frankfurt (FRA) to Turin Caselle Airport (TRN)plane plane FRA - TRN
    2. Take the train from Torino Porta Susa to Milano Centraletrain train
    3. Take the train from Milano Centrale to Luganotrain train
    7h 4m
    CHF 134–346

Mainz to Lugano by train

Calendar76Weekly Trains
Duration7h 12mAverage Duration
TicketCHF 51Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Lugano.ExpandLaunch map view
  • Distance: 575.3 km
  • Duration: 7h 12m

What companies run services between Mainz, Germany and Lugano, Switzerland?

You can take a train from Mainz, Hauptbahnhof to Lugano via Mannheim, Hauptbahnhof and Basel SBB in around 7h 12m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Lugano once daily. Tickets cost CHF 40–75 and the journey takes 8h 50m.

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