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How to get fromMainz to Luganoby train, bus, night train, car, or plane

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There are 10 ways to get from Mainz to Lugano by train, bus, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    7h 15m
    CHF 48–228

  2. Train, night train, bus

    cheapest
    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the nighttrain from Mannheim Hbf to Zuerich Hbnighttrain night train Nj
    3. Take the bus from Zürich Hbf to Lugano Stazionebus bus
    10h 16m
    CHF 37–119

  3. Bus

    1. Take the bus from Frankfurt central train station to Luganobus bus FlixBus N474
    10h 35m
    CHF 48–79

  4. Drive  587.6 km

    1. Drive from Mainz to Luganocar car 587.6 km
    5h 26m
    CHF 99–142

  5. Train via Zurich

    1. Take the train from Mainz Hbf to Zürich HBtrain train Nightjet
    2. Take the train from Zürich HB to Luganotrain train Ec / ...
    8h 46m
    CHF 101–172

  6. Fly Frankfurt to Zurich Airport, train

    1. Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane plane FRA - ZRH
    2. Take the train from Zürich HB to Luganotrain train
    4h 51m
    CHF 145–290

  7. Fly Frankfurt to Milano Malpensa Airport, train

    1. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    2. Take the train from Malpensa Aeroporto T1 to Luganotrain train
    5h 38m
    CHF 62–179

  8. Fly Frankfurt to Milan Linate Airport, train

    1. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    2. Take the train from Monza to Luganotrain train
    6h 4m
    CHF 38–152

  9. Fly Frankfurt to Basel, train

    1. Fly from Frankfurt (FRA) to Basel (BSL)plane plane FRA - BSL
    2. Take the train from Basel SBB to Luganotrain train
    6h 35m
    CHF 131–413

  10. Train to Stuttgart Airport, fly to Zurich Airport, train

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Zurich Airport (ZRH)plane plane STR - ZRH
    3. Take the train from Zürich HB to Luganotrain train
    6h 40m
    CHF 185–410

Mainz to Lugano by train

Calendar76Weekly Trains
Duration7h 15mAverage Duration
TicketCHF 48Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Lugano.ExpandLaunch map view
  • Distance: 575.5 km
  • Duration: 7h 15m

What companies run services between Mainz, Germany and Lugano, Switzerland?

You can take a train from Mainz, Hauptbahnhof to Lugano via Mannheim, Hauptbahnhof and Basel SBB in around 7h 15m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Lugano once daily. Tickets cost CHF 45–75 and the journey takes 8h 50m.

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Want to know more about travelling around Switzerland

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