There are 9 ways to get from Mainz to Lugano by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
- Take the train from Basel SBB to Luganotrain Ec
7h 58mCHF 65–161Bus
cheapest- Take the bus from Frankfurt central train station to Luganobus FlixBus N474
10h 30mCHF 37–64Drive 587.6 km
- Drive from Mainz to Luganocar 587.6 km
5h 26mCHF 92–132Fly to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich HB to Luganotrain
4h 52mCHF 129–299Train via Zurich
- Take the train from Mainz Hbf to Zürich HBtrain Nightjet
- Take the train from Zürich HB to Luganotrain Ec / ...
8h 47mCHF 118–326Train, bus
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim Hbf to Zuerich Hbtrain Ec
- Take the bus from Zurich Central Bus Station Sihlquai to Lugano Via Giacomo and Filippo Cianibus
11h 14mCHF 78–111Fly to Milano Malpensa Airport, train
- Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane FRA - MXP
- Take the train from Malpensa Aeroporto T1 to Luganotrain
5h 49mCHF 61–178Fly to Milan Linate Airport, train
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
- Take the train from Monza to Luganotrain
6h 6mCHF 42–141Fly to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Luganotrain
6h 35mCHF 137–289
Mainz to Lugano by train
Questions & Answers
The cheapest way to get from Mainz to Lugano is to bus which costs SFr 35 - SFr 65 and takes 10h 30m.
The fastest way to get from Mainz to Lugano is to fly and train which takes 4h 52m and costs SFr 120 - SFr 300.
No, there is no direct bus from Mainz station to Lugano. However, there are services departing from Mainz central train station and arriving at Lugano via Frankfurt central train station. The journey, including transfers, takes approximately 10h 30m.
No, there is no direct train from Mainz to Lugano. However, there are services departing from Mainz, Römisches Theater and arriving at Lugano via Mannheim, Hauptbahnhof and Basel SBB. The journey, including transfers, takes approximately 7h 58m.
The distance between Mainz and Lugano is 574 km. The road distance is 587.6 km.
The best way to get from Mainz to Lugano without a car is to train which takes 7h 58m and costs SFr 65 - SFr 170.
It takes approximately 7h 58m to get from Mainz to Lugano, including transfers.
Mainz to Lugano bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Lugano train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
The best way to get from Mainz to Lugano is to train which takes 7h 58m and costs SFr 65 - SFr 170. Alternatively, you can bus, which costs SFr 35 - SFr 65 and takes 10h 30m.
What companies run services between Mainz, Germany and Lugano, Switzerland?
You can take a train from Mainz, Römisches Theater to Lugano via Mannheim, Hauptbahnhof and Basel SBB in around 7h 58m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Lugano once daily. Tickets cost CHF 35–60 and the journey takes 8h 50m.
- Website
- lufthansa.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- CHF 60–280
Flights from Frankfurt to Zurich Airport via Munich
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- CHF 65–260
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 55–270
Flights from Frankfurt to Milano Malpensa Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Monday to Friday
- Estimated price
- CHF 75–290
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 55–210
Flights from Frankfurt to Milan Linate Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 55–240
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 70–330
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- CHF 75–310
- Website
- airdolomiti.it
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–280
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 70–270
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 55–210
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 85–330
- Website
- swiss.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- CHF 60–280
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Sunday
- Estimated price
- CHF 70–290
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 65–140
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- CHF 45–130
- Website
- easyjet.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 30–120
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- CHF 12–18
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Once daily
- Estimated price
- CHF 13–18
- Schedules at
- suewex.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- CHF 44–49
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- CHF 35–120
- Website
- https://www.ns.nl/en
- 2nd Class
- CHF 35–55
- 1st Class
- CHF 70–120
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- CHF 60–220
- Website
- https://www.ns.nl/en
- 2nd Class
- CHF 60–95
- 1st Class
- CHF 130–220
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 59m
- Frequency
- 5 times a week
- Estimated price
- CHF 45–60
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Mannheim Hbf to Zuerich Hb
- Ave. Duration
- 4h 43m
- Frequency
- 5 times a week
- Estimated price
- CHF 55–75
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- CHF 75–140
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 55–110
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- CHF 18–23
- Schedules at
- sbb-deutschland.de
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- https://www.trenord.it/en/
Train from Monza to Lugano
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- CHF 3–5
- Website
- https://www.trenord.it/en/
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Frankfurt central train station to Lugano
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- CHF 35–60
- Website
- https://www.flixbus.co.uk
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Zurich Central Bus Station Sihlquai to Lugano Via Giacomo and Filippo Ciani
- Ave. Duration
- 3h 5m
- Frequency
- Once a week
- Estimated price
- CHF 11–18
- Website
- https://regiojet.com/
Want to know more about travelling around Switzerland
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More Questions & Answers
Mainz to Lugano bus services, operated by FlixBus, arrive at Lugano station.
Mainz to Lugano train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Lugano is 588 km. It takes approximately 5h 26m to drive from Mainz to Lugano.
Book your Mainz to Lugano train tickets online with Omio.
Book your Mainz to Lugano bus tickets online with FlixBus.
There are 6297+ hotels available in Lugano.










































