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How to get fromMainz to Luganoby train, bus, car, plane, or night train

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There are 9 ways to get from Mainz to Lugano by train, bus, car, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    7h 14m
    CHF 53–480

  2. Fly to Milan Linate Airport, train

    cheapest
    1. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    2. Take the train from Monza to Luganotrain train
    5h 49m
    CHF 47–163

  3. Bus

    1. Take the bus from Frankfurt central train station to Luganobus bus FlixBus N474
    10h 35m
    CHF 48–79

  4. Drive 587.6 km

    1. Drive from Mainz to Luganocar car 587.6 km
    5h 26m
    CHF 97–140

  5. Fly to Zurich Airport, train

    1. Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane plane FRA - ZRH
    2. Take the train from Zürich HB to Luganotrain train
    4h 52m
    CHF 144–382

  6. Train via Zurich

    1. Take the train from Mainz Hbf to Zürich HBtrain train Nightjet
    2. Take the train from Zürich HB to Luganotrain train Ec / ...
    8h 46m
    CHF 104–286

  7. Train, night train, bus

    1. Take the train from Mainz, Römisches Theater to Karlsruhe Hauptbahnhoftrain train S6
    2. Take the nighttrain from Karlsruhe Hbf to Zuerich Hbnighttrain night train Nj
    3. Take the bus from Zürich Hbf to Lugano Stazionebus bus
    10h 53m
    CHF 59–146

  8. Fly to Milano Malpensa Airport, train

    1. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    2. Take the train from Malpensa Aeroporto T1 to Luganotrain train
    5h 39m
    CHF 66–190

  9. Fly to Basel, train

    1. Fly from Frankfurt (FRA) to Basel (BSL)plane plane FRA - BSL
    2. Take the train from Basel SBB to Luganotrain train
    6h 35m
    CHF 136–553

Mainz to Lugano by train

Calendar76Weekly Trains
Duration7h 14mAverage Duration
TicketCHF 53Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Lugano.ExpandLaunch map view
  • Distance: 575.5 km
  • Duration: 7h 14m

What companies run services between Mainz, Germany and Lugano, Switzerland?

You can take a train from Mainz, Hauptbahnhof to Lugano via Mannheim, Hauptbahnhof and Basel SBB in around 7h 14m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Lugano once daily. Tickets cost CHF 45–75 and the journey takes 8h 50m.

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