There are 9 ways to get from Mainz to Lugano by train, bus, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
7h 13mCHF 50–402Bus
cheapest- Take the bus from Frankfurt central train station to Luganobus FlixBus N474
10h 40mCHF 42–74Train, night train, bus
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the night train from Mannheim Hbf to Zuerich Hbnighttrain Nj
- Take the bus from Zürich to Luganobus
10h 57mCHF 52–134Drive 587.6 km
- Drive from Mainz to Luganocar 587.6 km
5h 26mCHF 96–139Train via Zurich
- Take the train from Mainz Hbf to Zürich HBtrain Nightjet
- Take the train from Zürich HB to Luganotrain Ec / ...
8h 46mCHF 107–272Fly to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich HB to Luganotrain
4h 51mCHF 153–411Fly to Milano Malpensa Airport, train
- Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane FRA - MXP
- Take the train from Malpensa Aeroporto T1 to Luganotrain
5h 38mCHF 80–198Fly to Milan Linate Airport, train
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
- Take the train from Monza to Luganotrain
5h 55mCHF 46–201Fly to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Luganotrain
6h 35mCHF 136–576
Mainz to Lugano by train
Questions & Answers
The cheapest way to get from Mainz to Lugano is to bus which costs SFr 40 - SFr 75 and takes 10h 40m.
The fastest way to get from Mainz to Lugano is to fly and train which takes 4h 51m and costs SFr 150 - SFr 420.
No, there is no direct bus from Mainz station to Lugano. However, there are services departing from Mainz central train station and arriving at Lugano via Frankfurt central train station. The journey, including transfers, takes approximately 10h 40m.
No, there is no direct train from Mainz to Lugano. However, there are services departing from Mainz, Hauptbahnhof and arriving at Lugano via Mannheim, Hauptbahnhof and Basel SBB. The journey, including transfers, takes approximately 7h 13m.
The distance between Mainz and Lugano is 575 km. The road distance is 587.6 km.
The best way to get from Mainz to Lugano without a car is to train which takes 7h 13m and costs SFr 50 - SFr 410.
It takes approximately 7h 13m to get from Mainz to Lugano, including transfers.
Mainz to Lugano bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Lugano train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Lugano is to train which takes 7h 13m and costs SFr 50 - SFr 410. Alternatively, you can bus, which costs SFr 40 - SFr 75 and takes 10h 40m.
What companies run services between Mainz, Germany and Lugano, Switzerland?
You can take a train from Mainz, Hauptbahnhof to Lugano via Mannheim, Hauptbahnhof and Basel SBB in around 7h 13m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Lugano once daily. Tickets cost CHF 40–70 and the journey takes 8h 50m.
- Website
- lufthansa.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- CHF 65–460
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- CHF 70–430
Flights from Frankfurt to Milano Malpensa Airport via Munich
- Ave. Duration
- 2h 57m
- When
- Every day
- Estimated price
- CHF 110–480
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 100–550
Flights from Frankfurt to Basel
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- CHF 75–550
- Website
- swiss.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- CHF 65–460
Flights from Frankfurt to Milano Malpensa Airport via Zurich Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- CHF 75–290
Flights from Frankfurt to Basel
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- CHF 75–140
- Website
- airdolomiti.it
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Sunday
- Estimated price
- CHF 90–460
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- CHF 95–430
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 100–550
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Monday, Saturday, and Sunday
- Estimated price
- CHF 110–550
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 80–190
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- CHF 60–170
- Website
- easyjet.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- CHF 35–160
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- CHF 11–35
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- CHF 40–120
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- CHF 13–20
- Website
- https://int.bahn.de/en
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- CHF 13–20
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Every 4 hours
- Estimated price
- CHF 13–19
- Schedules at
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- CHF 13–19
- Schedules at
- suewex.de
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- CHF 7–16
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- CHF 25–60
- Website
- https://www.ns.nl/en
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- CHF 45–110
- Website
- https://www.ns.nl/en
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- CHF 85–250
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 60–170
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- CHF 18–23
- Schedules at
- sbb-deutschland.de
- Phone
- +43 (0) 51717
- Website
- nightjet.com
Night train from Mannheim Hbf to Zuerich Hb
- Ave. Duration
- 4h 46m
- Frequency
- 6 times a week
- Estimated price
- CHF 25–88
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- CHF 86–88
- Couchette Carriage
- CHF 50–65
- Seating Carriage
- CHF 25–30
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- https://www.trenord.it/en/
Train from Monza to Lugano
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- CHF 3–5
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Monza to Lugano
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- CHF 9–15
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 9–13
- 2nd Class
- CHF 11–15
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Frankfurt central train station to Lugano
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- CHF 40–70
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Zürich to Lugano
- Ave. Duration
- 2h 45m
- Frequency
- 5 times a day
- Estimated price
- CHF 14–25
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italian Lakes: Getting around by train
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Mainz to Lugano bus services, operated by FlixBus, arrive at Lugano station.
Mainz to Lugano train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Lugano is 588 km. It takes approximately 5h 26m to drive from Mainz to Lugano.
Book your Mainz to Lugano train tickets online with Omio.
Book your Mainz to Lugano bus tickets online with Omio and FlixBus.
There are 7138+ hotels available in Lugano.






















































