There are 9 ways to get from Mainz to Lugano by train, bus, car, plane, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhofS6 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBB20 / ...
- Take the train from Basel SBB to LuganoEc
7h 58mCHF 60–248Bus
cheapest- Take the bus from Frankfurt central train station to LuganoN474
10h 30mCHF 35–87Drive 587.6 km
- Drive from Mainz to Lugano587.6 km
5h 26mCHF 94–135Fly to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)FRA - ZRH
- Take the train from Zürich HB to Lugano
4h 51mCHF 120–275Train via Zurich
- Take the train from Mainz Hbf to Zürich HBNightjet
- Take the train from Zürich HB to LuganoIc2 / ...
8h 45mCHF 105–295Train, night train
- Take the train from Mainz, Römisches Theater to Ludwigshafen, MitteS6 / ...
- Take the train from Ludwigshafen, Mitte to Karlsruhe HauptbahnhofS3 / ...
- Take the night train from Karlsruhe Hbf to Zuerich HbNj
- Take the train from Zürich HB to LuganoEcm
10h 38mCHF 68–305Fly to Milano Malpensa Airport, train
- Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)FRA - MXP
- Take the train from Malpensa Aeroporto T1 to Lugano
5h 49mCHF 72–159Fly to Milan Linate Airport, train
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)FRA - LIN
- Take the train from Monza to Lugano
5h 58mCHF 48–152Fly to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)FRA - BSL
- Take the train from Basel SBB to Lugano
6h 37mCHF 138–367
Mainz to Lugano by train
Questions & Answers
The cheapest way to get from Mainz to Lugano is to bus which costs SFr 35 - SFr 90 and takes 10h 30m.
The fastest way to get from Mainz to Lugano is to fly and train which takes 4h 51m and costs SFr 120 - SFr 280.
No, there is no direct bus from Mainz station to Lugano. However, there are services departing from Mainz central train station and arriving at Lugano via Frankfurt central train station. The journey, including transfers, takes approximately 10h 30m.
No, there is no direct train from Mainz to Lugano. However, there are services departing from Mainz, Römisches Theater and arriving at Lugano via Mannheim, Hauptbahnhof and Basel SBB. The journey, including transfers, takes approximately 7h 58m.
The distance between Mainz and Lugano is 573 km. The road distance is 587.6 km.
The best way to get from Mainz to Lugano without a car is to train which takes 7h 58m and costs SFr 55 - SFr 250.
It takes approximately 7h 58m to get from Mainz to Lugano, including transfers.
Mainz to Lugano bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Lugano train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
The best way to get from Mainz to Lugano is to train which takes 7h 58m and costs SFr 55 - SFr 250. Alternatively, you can bus, which costs SFr 35 - SFr 90 and takes 10h 30m.
What companies run services between Mainz, Germany and Lugano, Switzerland?
You can take a train from Mainz, Römisches Theater to Lugano via Mannheim, Hauptbahnhof and Basel SBB in around 7h 58m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Lugano once daily. Tickets cost CHF 30–80 and the journey takes 8h 50m.
- Website
- lufthansa.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- CHF 65–280
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 65–260
Flights from Frankfurt to Milano Malpensa Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Wednesday and Thursday
- Estimated price
- CHF 80–270
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 70–140
Flights from Frankfurt to Milan Linate Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 60–110
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 60–470
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- CHF 60–470
- Website
- airdolomiti.it
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 85–280
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 80–260
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 70–140
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 95–310
- Website
- swiss.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- CHF 65–280
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 60–470
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 65–180
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- CHF 40–120
- Website
- easyjet.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 35–110
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- CHF 12–18
- Website
- https://int.bahn.de/en
Train from Mainz, Römisches Theater to Ludwigshafen, Mitte
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- CHF 12–18
- Website
- https://int.bahn.de/en
Train from Ludwigshafen, Mitte to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- CHF 13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- CHF 13–19
- Schedules at
- suewex.de
Train from Mainz, Römisches Theater to Ludwigshafen, Mitte
- Ave. Duration
- 57 min
- Frequency
- Twice daily
- Estimated price
- CHF 13–18
- Schedules at
- suewex.de
Train from Ludwigshafen, Mitte to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 3m
- Frequency
- 5 times a week
- Estimated price
- CHF 13–19
- Schedules at
- suewex.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- CHF 29–80
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- CHF 35–130
- Website
- https://www.ns.nl/en
- 2nd Class
- CHF 35–55
- 1st Class
- CHF 75–130
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Twice daily
- Estimated price
- CHF 65–220
- Website
- https://www.ns.nl/en
- 2nd Class
- CHF 65–95
- 1st Class
- CHF 130–220
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 55m
- Frequency
- Every 2 hours
- Estimated price
- CHF 50–100
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- CHF 40–75
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- CHF 18–24
- Schedules at
- sbb-deutschland.de
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- CHF 13–18
- Schedules at
- sbb-deutschland.de
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Karlsruhe Hbf to Zuerich Hb
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- CHF 30–242
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- CHF 239–242
- Couchette Carriage
- CHF 120–140
- Seating Carriage
- CHF 30–45
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- https://www.trenord.it/en/
Train from Monza to Lugano
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- CHF 3–5
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Monza to Lugano
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- CHF 9–15
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 9–13
- 2nd Class
- CHF 11–15
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Frankfurt central train station to Lugano
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- CHF 30–80
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Switzerland
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More Questions & Answers
Mainz to Lugano bus services, operated by FlixBus, arrive at Lugano station.
Mainz to Lugano train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Lugano is 588 km. It takes approximately 5h 26m to drive from Mainz to Lugano.
Book your Mainz to Lugano train tickets online with Omio.
Book your Mainz to Lugano bus tickets online with FlixBus.
There are 5852+ hotels available in Lugano.















































