There are 10 ways to get from Mainz to Lugano by train, bus, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
7h 14mCHF 50–251Fly Frankfurt to Milan Linate Airport, train
cheapest- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
- Take the train from Monza to Luganotrain
6h 4mCHF 40–165Bus
- Take the bus from Frankfurt central train station to Luganobus FlixBus N474
10h 20mCHF 60–85Night train, train
- Take the nighttrain from Mainz Hbf to Zuerich Hbnighttrain Nj
- Take the train from Zürich HB to Luganotrain Ec / ...
8h 46mCHF 89–178Drive 587.6 km
- Drive from Mainz to Luganocar 587.6 km
5h 26mCHF 98–142Train, bus
- Take the train from Mainz Hbf to Zürich HBtrain Nightjet
- Take the bus from Zürich Hbf to Lugano Stazionebus
9h 53mCHF 53–101Fly Frankfurt to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich HB to Luganotrain
4h 51mCHF 157–308Fly Frankfurt to Milano Malpensa Airport, train
- Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane FRA - MXP
- Take the train from Malpensa Aeroporto T1 to Luganotrain
5h 48mCHF 59–182Fly Frankfurt to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Luganotrain
6h 34mCHF 133–466Train to Stuttgart Airport, fly to Zurich Airport, train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Zurich Airport (ZRH)plane STR - ZRH
- Take the train from Zürich HB to Luganotrain
6h 40mCHF 194–424
Mainz to Lugano by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Lugano is to train and bus which costs SFr 50 - SFr 110 and takes 9h 53m.
The fastest way to get from Mainz to Lugano is to fly and train which takes 4h 51m and costs SFr 150 - SFr 310.
No, there is no direct bus from Mainz station to Lugano. However, there are services departing from Frankfurt central train station and arriving at Lugano via . The journey, including transfers, takes approximately 10h 20m.
No, there is no direct train from Mainz to Lugano. However, there are services departing from Mainz, Hauptbahnhof and arriving at Lugano via Mannheim, Hauptbahnhof and Basel SBB. The journey, including transfers, takes approximately 7h 14m.
The distance between Mainz and Lugano is 575 km. The road distance is 587.6 km.
The best way to get from Mainz to Lugano without a car is to train which takes 7h 14m and costs SFr 50 - SFr 260.
It takes approximately 7h 14m to get from Mainz to Lugano, including transfers.
Mainz to Lugano bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Lugano train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Lugano is to train which takes 7h 14m and costs SFr 50 - SFr 260. Alternatively, you can bus, which costs SFr 60 - SFr 90 and takes 10h 20m.
What companies run services between Mainz, Germany and Lugano, Switzerland?
You can take a train from Mainz, Hauptbahnhof to Lugano via Mannheim, Hauptbahnhof and Basel SBB in around 7h 14m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Lugano once daily. Tickets cost CHF 50–75 and the journey takes 8h 50m.
- Website
- lufthansa.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–350
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- CHF 70–340
Flights from Frankfurt to Milano Malpensa Airport via Munich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- CHF 70–370
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 50–400
Flights from Frankfurt to Basel
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- CHF 75–420
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- CHF 75–420
Flights from Stuttgart Airport to Zurich Airport
- Ave. Duration
- 45 min
- When
- Saturday
- Estimated price
- CHF 60–340
- Website
- swiss.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–350
Flights from Frankfurt to Milano Malpensa Airport via Zurich Airport
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- CHF 70–170
Flights from Frankfurt to Basel
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- CHF 75–420
Flights from Stuttgart Airport to Zurich Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- CHF 60–340
- Website
- airdolomiti.it
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 120–350
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- CHF 110–340
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 50–400
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 130–380
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 90–200
Flights from Frankfurt to Milano Malpensa Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- CHF 50–150
- Website
- easyjet.com
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- CHF 30–130
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 11–24
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- CHF 40–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- CHF 28–65
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- CHF 10–45
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 13–19
- Schedules at
- Süwex
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- CHF 7–14
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- CHF 25–50
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- CHF 45–95
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Twice daily
- Estimated price
- CHF 45–95
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- CHF 85–120
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 60–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 60–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- CHF 85–120
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 60–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- CHF 18–24
- Schedules at
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- CHF 18–24
- Schedules at
- SBB GmbH
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- 3 times a week
- Estimated price
- CHF 29–93
- Website
- Nightjet
- Sleeper Carriage
- CHF 90–93
- Couchette Carriage
- CHF 55–70
- Seating Carriage
- CHF 29–35
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Lugano
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- CHF 5–7
- Website
- Trenord
Train from Monza to Lugano
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- CHF 3–5
- Website
- Trenord
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Frankfurt central train station to Lugano
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- CHF 50–75
- Website
- Flixbus
- Phone
- + 381 31 510 060
- zlatanprevoz@gmail.com
- Website
- facebook.com
Bus from Zürich Hbf to Lugano Stazione
- Ave. Duration
- 2h 31m
- Frequency
- Once a week
- Estimated price
- CHF 7–11
- Schedules at
- facebook.com
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italian Lakes: Getting around by train
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Mainz to Lugano bus services, operated by FlixBus, arrive at Lugano station.
Mainz to Lugano train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Lugano is 588 km. It takes approximately 5h 26m to drive from Mainz to Lugano.
Book your Mainz to Lugano train tickets online with Omio.
Book your Mainz to Lugano bus tickets online with Omio.
There are 6667+ hotels available in Lugano.






































