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How to get fromMainz to Domodossolaby train, car, plane or bus

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There are 8 ways to get from Mainz to Domodossola by train, car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Spiez

    best
    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain20 / ...
    3. Take the train from Basel SBB to SpieztrainIc6 / ...
    4. Take the train from Spiez to DomodossolatrainEc / ...
    7h 52m
    €73–295
  2. Fly to Milano Malpensa Airport, bus

    cheapest
    1. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)planeFRA - MXP
    2. Take the bus from Aeroporto Malpensa - Terminal 1 to Domodossola - Stazione Ferroviariabus
    5h 54m
    €71–161
  3. Drive 629.1 km

    1. Drive from Mainz to Domodossolacar629.1 km
    6h 16m
    €99–142
  4. Train

    1. Take the train from Mainz Hbf to Zürich HBtrainNightjet
    2. Take the train from Zürich HB to DomodossolatrainIc
    9h 59m
    €125–347
  5. Fly to Zurich Airport, train

    1. Fly from Frankfurt (FRA) to Zurich Airport (ZRH)planeFRA - ZRH
    2. Take the train from Zürich Flughafen to Brigtrain
    6h 32m
    €147–312
  6. Fly to Milan Linate Airport, train

    1. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)planeFRA - LIN
    2. Take the train from Milano Centrale to Domodossolatrain
    6h 34m
    €74–221
  7. Fly to Basel, train

    1. Fly from Frankfurt (FRA) to Basel (BSL)planeFRA - BSL
    2. Take the train from Basel SBB to Brigtrain
    6h 54m
    €148–407
  8. Fly to Geneva International Airport, train

    1. Fly from Frankfurt (FRA) to Geneva International Airport (GVA)planeFRA - GVA
    2. Take the train from Genève-Aéroport to Brigtrain
    7h 47m
    €152–342

Mainz to Domodossola by train

Calendar143Weekly Trains
Duration7h 52mAverage Duration
Ticket€73Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Domodossola, Italy?

You can take a train from Mainz, Römisches Theater to Domodossola via Mannheim, Hauptbahnhof, Basel SBB, and Spiez in around 7h 52m.

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