There are 10 ways to get from Maine to South Carolina by plane, car, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Portland to Charlotte  •  4 h 3 min

  1. Fly from Portland (PWM) to Charlotte (CLT) PWM - CLT

$229 - $735

Cheapest option

Bus Wanda Coach  •  21 h 49 min

  1. Take the bus from Portland, ME to Logan Airport
  2. Take the bus from Boston, MA to New York
  3. Take the bus from New York, NY to Florence, SC Nyc

$113 - $128

8 alternative options

Drive to Manchester, fly to Charlotte  •  4 h 25 min

  1. Drive from Sanford to Manchester
  2. Fly from Manchester (MHT) to Charlotte (CLT) MHT - CLT

$191 - $649

Fly Bangor to Charlotte  •  4 h 51 min

  1. Fly from Bangor (BGR) to Charlotte (CLT) BGR - CLT

$316 - $1,292

Fly Portland to Charleston  •  6 h 8 min

  1. Fly from Portland (PWM) to Charleston (CHS) PWM - CHS

$272 - $1,200

Bus to Boston, fly to Charlotte  •  6 h 11 min

  1. Take the bus from Wells to Boston, Ma
  2. Fly from Boston (BOS) to Charlotte (CLT) BOS - CLT

$218 - $616

Bus to Boston, fly to Charleston  •  6 h 52 min

  1. Take the bus from Wells to Boston, Ma
  2. Fly from Boston (BOS) to Charleston (CHS) BOS - CHS

$180 - $569

Bus, train  •  20 h 11 min

  1. Take the bus from Portland, Me to Boston, Ma
  2. Take the train from Boston South Station to New York Penn Station
  3. Take the train from New York Penn Station to Florence Amtrak

$182 - $457

Bus Greyhound USA  •  23 h 12 min

  1. Take the bus from Portland, Me to Boston, Ma
  2. Take the bus from Boston, MA - South Station to New York City, NY - Port Authority Bus Terminal
  3. Take the bus from New York, Ny to Fayetteville, Nc
  4. Take the bus from Fayetteville, Nc to Florence, Sc

$117 - $243

Drive  •  16 h 5 min

  1. Drive from Portland to Florence 952 miles

$90 - $140

Questions & Answers

The cheapest way to get from Maine to South Carolina is to drive which costs $90 - $140 and takes 16 h 5 min.

More details

The quickest way to get from Maine to South Carolina is to fly which costs $220 - $750 and takes 4 h 3 min.

More details

No, there is no direct bus from Maine to South Carolina. However, there are services departing from City Hall and arriving at Florence, Sc via Portland, Me, Boston, MA - South Station, New York, Ny and Fayetteville, Nc. The journey, including transfers, takes approximately 23 h 12 min.

More details

The distance between Maine and South Carolina is 1037 miles. The road distance is 952 miles.

Get driving directions

The best way to get from Maine to South Carolina without a car is to bus and train which takes 20 h 11 min and costs $180 - $460.

More details

It takes approximately 4 h 3 min to get from Maine to South Carolina, including transfers.

More details

Maine to South Carolina bus services, operated by Greyhound USA, depart from Portland, Me station.

More details

The best way to get from Maine to South Carolina is to fly which takes 4 h 3 min and costs $220 - $750. Alternatively, you can bus, which costs $110 - $130 and takes 21 h 49 min.

Mode details

Map of how to get from Maine to South Carolina.
Launch map view
  • Distance: 1037.5 miles
  • Duration: 4 h 3 min

What companies run services between Maine, USA and South Carolina, USA?

American Airlines, Southwest Airlines and three other airlines fly from South Portland Gardens to Rock Hill hourly. Alternatively, you can take a bus from Portland to Florence via Congress St + Valley St, Portland, ME, Logan Airport, Terminal A, South Station, Boston, MA, New York, New York, NY, and Florence, SC in around 21 h 49 min.

Airlines
American Airlines
Website
aa.com
Flights from Portland to Charlotte
Ave. Duration
2 h 34 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Charlotte via Reagan Washington
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$290 - $1,300
Flights from Manchester to Charlotte
Ave. Duration
2 h 31 min
When
Every day
Estimated price
$190 - $950
Flights from Manchester to Charlotte via Reagan Washington
Ave. Duration
4 h 40 min
When
Every day
Estimated price
$190 - $950
Flights from Manchester to Charlotte via Philadelphia
Ave. Duration
4 h 59 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $950
Flights from Bangor to Charlotte
Ave. Duration
2 h 58 min
When
Every day
Estimated price
$260 - $1,200
Flights from Bangor to Charlotte via Reagan Washington
Ave. Duration
4 h 47 min
When
Every day
Estimated price
$260 - $1,200
Flights from Bangor to Charlotte via Philadelphia
Ave. Duration
5 h 28 min
When
Every day
Estimated price
$260 - $1,200
Flights from Bangor to Charlotte via New York La Guardia
Ave. Duration
5 h 45 min
When
Every day
Estimated price
$260 - $1,200
Flights from Portland to Charleston via Reagan Washington
Ave. Duration
4 h 46 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Charleston via Philadelphia
Ave. Duration
4 h 54 min
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$290 - $1,300
Flights from Portland to Charleston via Charlotte
Ave. Duration
5 h 27 min
When
Every day
Estimated price
$290 - $1,300
Flights from Boston to Charlotte
Ave. Duration
2 h 26 min
When
Every day
Estimated price
$95 - $900
Flights from Boston to Charleston via Charlotte
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$150 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Portland to Charlotte via Baltimore
Ave. Duration
4 h 7 min
When
Monday to Saturday
Estimated price
$260 - $1,200
Flights from Manchester to Charlotte via Baltimore
Ave. Duration
4 h 10 min
When
Monday to Saturday
Estimated price
$260 - $1,400
Flights from Portland to Charleston via Baltimore
Ave. Duration
4 h 48 min
When
Every day
Estimated price
$320 - $1,300
Flights from Boston to Charlotte via Baltimore
Ave. Duration
3 h 56 min
When
Monday to Saturday
Estimated price
$250 - $1,300
Flights from Boston to Charleston via Baltimore
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$290 - $1,200
United Airlines
Website
united.com
Flights from Portland to Charlotte via Washington Dulles
Ave. Duration
4 h 15 min
When
Every day
Estimated price
$210 - $1,400
Flights from Portland to Charlotte via Newark
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$210 - $1,400
Flights from Manchester to Charlotte via Newark
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$180 - $1,400
Flights from Bangor to Charlotte via Newark
Ave. Duration
5 h 22 min
When
Every day
Estimated price
$270 - $1,300
Flights from Portland to Charleston via Washington Dulles
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$300 - $1,400
Flights from Portland to Charleston via Newark
Ave. Duration
5 h 37 min
When
Every day
Estimated price
$300 - $1,400
Flights from Boston to Charlotte via Washington Dulles
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$140 - $1,200
Flights from Boston to Charlotte via Newark
Ave. Duration
4 h 7 min
When
Monday to Friday
Estimated price
$140 - $1,200
Flights from Boston to Charleston via Washington Dulles
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$190 - $1,200
Flights from Boston to Charleston via Newark
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$190 - $1,200
Delta
Website
delta.com
Flights from Portland to Charlotte via New York La Guardia
Ave. Duration
4 h 34 min
When
Saturday
Estimated price
$220 - $1,500
Flights from Manchester to Charlotte via Detroit
Ave. Duration
4 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $950
Flights from Manchester to Charlotte via Atlanta
Ave. Duration
4 h 59 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $950
Flights from Bangor to Charlotte via New York La Guardia
Ave. Duration
5 h 32 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,200
Flights from Bangor to Charlotte via New York JFK
Ave. Duration
5 h 54 min
When
Every day
Estimated price
$240 - $1,200
Flights from Portland to Charleston via New York La Guardia
Ave. Duration
5 h 8 min
When
Every day
Estimated price
$270 - $1,300
Flights from Portland to Charleston via Atlanta
Ave. Duration
5 h 27 min
When
Every day
Estimated price
$300 - $1,400
Flights from Portland to Charleston via Detroit
Ave. Duration
5 h 36 min
When
Every day
Estimated price
$310 - $1,400
Flights from Boston to Charleston
Ave. Duration
2 h 25 min
When
Every day
Estimated price
$180 - $1,200
JetBlue Airways
Website
jetblue.com
Flights from Portland to Charleston via New York JFK
Ave. Duration
5 h 43 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,200
Flights from Boston to Charlotte
Ave. Duration
2 h 24 min
When
Every day
Estimated price
$140 - $1,000
Flights from Boston to Charlotte via New York JFK
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$140 - $1,000
Flights from Boston to Charleston
Ave. Duration
2 h 28 min
When
Every day
Estimated price
$190 - $1,000
Flights from Boston to Charleston via Reagan Washington
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$190 - $1,000
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Boston South Station to New York Penn Station
Ave. Duration
3 h 40 min
Frequency
Every 4 hours
Estimated price
$75 - $160
Website
amtrak.com
Coach
$75 - $160
Business Class
$110 - $200
First Class
$291
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Florence Amtrak
Ave. Duration
11 h 50 min
Frequency
Twice daily
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Wells to Boston, Ma
Ave. Duration
1 h 35 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$24 - $35
Bus from Portland, Me to Boston, Ma
Ave. Duration
2 h 10 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Bus from New York, Ny to Fayetteville, Nc
Ave. Duration
13 h 45 min
Frequency
Hourly
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1 h 35 min
Frequency
Every 30 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35
Concord Coach Lines
Lucky Star Bus
Phone
(888) 881-0887 / (617) 269-5468
Email
info@luckystarbus.com
Website
luckystarbus.com
Bus from Boston, MA to New York
Ave. Duration
4 h 30 min
Frequency
Every 2 hours
Estimated price
$25
Schedules at
luckystarbus.com
Wanda Coach
Phone
6466307186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from New York, NY to Florence, SC
Ave. Duration
11 h 45 min
Frequency
5 times a day
Estimated price
$55
Schedules at
wandacoach.com
Starline Bus
Website
starlinebus.com
Bus from New York, NY to Florence, SC
Ave. Duration
11 h 15 min
Frequency
Twice daily
Estimated price
$55
Schedules at
starlinebus.com
Book at
gotobus.com
bus
Bus from Boston, MA - South Station to New York City, NY - Port Authority Bus Terminal
Ave. Duration
3 h 45 min
Frequency
Hourly
Estimated price
$31

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