There are 10 ways to get from Maine to South Carolina by plane, car, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Portland to Charlotte  •  4 h 5 min

  1. PWM - CLT

$226 - $743

Cheapest option

Bus Megabus  •  25 h 20 min

$98 - $186

8 alternative options

Fly Bangor to Charlotte  •  4 h 45 min

  1. BGR - CLT

$316 - $1,292

Fly Portland to Charleston  •  6 h 18 min

  1. PWM - CHS

$274 - $1,206

Drive to Manchester, fly to Charlotte  •  4 h 26 min

  1. MHT - CLT

$191 - $649

Bus to Boston, fly to Charlotte  •  6 h 12 min

  1. BOS - CLT

$219 - $616

Bus to Boston, fly to Charleston  •  6 h 55 min

  1. BOS - CHS

$181 - $569

Bus, train  •  19 h 59 min

$182 - $463

Bus via Boston, Ma  •  23 h 20 min

$108 - $283

Drive  •  16 h 5 min

  1. 952 miles

$90 - $140

What companies run services between Maine, USA and South Carolina, USA?

American Airlines, Southwest Airlines and three other airlines fly from South Portland Gardens to Rock Hill hourly. Alternatively, you can take a bus from Portland to Florence via Congress St + Valley St, Portland, Me, Boston, Ma, New York, Ny, and Fayetteville, Nc in around 23 h 20 min.

Airlines
American Airlines
Website
aa.com
Flights from Portland to Charlotte
Ave. Duration
2 h 32 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Charlotte via Philadelphia
Ave. Duration
4 h 26 min
When
Monday to Saturday
Estimated price
$290 - $1,300
Flights from Portland to Charlotte via Reagan Washington
Ave. Duration
4 h 36 min
When
Every day
Estimated price
$290 - $1,300
Flights from Bangor to Charlotte
Ave. Duration
2 h 52 min
When
Every day
Estimated price
$260 - $1,200
Flights from Bangor to Charlotte via Reagan Washington
Ave. Duration
4 h 43 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,200
Flights from Bangor to Charlotte via Philadelphia
Ave. Duration
5 h 38 min
When
Every day
Estimated price
$260 - $1,200
Flights from Bangor to Charlotte via New York La Guardia
Ave. Duration
4 h 59 min
When
Saturday and Sunday
Estimated price
$260 - $1,200
Flights from Portland to Charleston via Charlotte
Ave. Duration
5 h 13 min
When
Every day
Estimated price
$290 - $1,300
Flights from Portland to Charleston via Reagan Washington
Ave. Duration
5 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $1,300
Flights from Portland to Charleston via Philadelphia
Ave. Duration
6 h 36 min
When
Saturday
Estimated price
$290 - $1,300
Flights from Manchester to Charlotte
Ave. Duration
2 h 30 min
When
Every day
Estimated price
$190 - $950
Flights from Manchester to Charlotte via Reagan Washington
Ave. Duration
4 h 24 min
When
Every day
Estimated price
$190 - $950
Flights from Manchester to Charlotte via Philadelphia
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$190 - $950
Flights from Boston to Charlotte
Ave. Duration
2 h 26 min
When
Every day
Estimated price
$95 - $900
Flights from Boston to Charlotte via Reagan Washington
Ave. Duration
4 h 10 min
When
Monday to Friday
Estimated price
$95 - $900
Flights from Boston to Charleston via Charlotte
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$150 - $1,100
Flights from Boston to Charleston via Philadelphia
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$150 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Portland to Charlotte via Baltimore
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$260 - $1,200
Flights from Portland to Charleston via Baltimore
Ave. Duration
4 h 53 min
When
Every day
Estimated price
$320 - $1,300
Flights from Manchester to Charlotte via Baltimore
Ave. Duration
4 h 1 min
When
Monday to Saturday
Estimated price
$260 - $1,400
Flights from Boston to Charlotte via Baltimore
Ave. Duration
4 h 2 min
When
Monday to Saturday
Estimated price
$250 - $1,300
Flights from Boston to Charleston via Baltimore
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$290 - $1,200
Delta
Website
delta.com
Flights from Portland to Charlotte via New York JFK
Ave. Duration
4 h 32 min
When
Monday to Saturday
Estimated price
$220 - $1,500
Flights from Portland to Charlotte via New York La Guardia
Ave. Duration
4 h 41 min
When
Saturday
Estimated price
$220 - $1,500
Flights from Bangor to Charlotte via New York La Guardia
Ave. Duration
5 h 33 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,200
Flights from Bangor to Charlotte via New York JFK
Ave. Duration
5 h 48 min
When
Every day
Estimated price
$240 - $1,200
Flights from Portland to Charleston via New York La Guardia
Ave. Duration
5 h 9 min
When
Every day
Estimated price
$270 - $1,300
Flights from Portland to Charleston via Atlanta
Ave. Duration
5 h 43 min
When
Every day
Estimated price
$300 - $1,400
Flights from Portland to Charleston via Detroit
Ave. Duration
6 h 16 min
When
Every day
Estimated price
$310 - $1,400
Flights from Manchester to Charlotte via New York La Guardia
Ave. Duration
4 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $950
Flights from Boston to Charleston
Ave. Duration
2 h 31 min
When
Saturday
Estimated price
$180 - $1,200
United Airlines
Website
united.com
Flights from Portland to Charlotte via Washington Dulles
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$210 - $1,400
Flights from Portland to Charlotte via Newark
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$210 - $1,400
Flights from Bangor to Charlotte via Newark
Ave. Duration
5 h 58 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,300
Flights from Portland to Charleston via Washington Dulles
Ave. Duration
4 h 24 min
When
Sunday
Estimated price
$300 - $1,400
Flights from Portland to Charleston via Newark
Ave. Duration
4 h 56 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,400
Flights from Manchester to Charlotte via Newark
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$180 - $1,400
Flights from Boston to Charlotte via Washington Dulles
Ave. Duration
4 h 1 min
When
Every day
Estimated price
$140 - $1,200
Flights from Boston to Charleston via Newark
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$190 - $1,200
Flights from Boston to Charleston via Washington Dulles
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$190 - $1,200
JetBlue Airways
Website
jetblue.com
Flights from Portland to Charlotte via New York JFK
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$200 - $1,700
Flights from Portland to Charleston via New York JFK
Ave. Duration
6 h 42 min
When
Every day
Estimated price
$270 - $1,200
Flights from Boston to Charlotte
Ave. Duration
2 h 20 min
When
Every day
Estimated price
$140 - $1,000
Flights from Boston to Charlotte via New York JFK
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$140 - $1,000
Flights from Boston to Charleston
Ave. Duration
2 h 28 min
When
Every day
Estimated price
$190 - $1,000
Train operators
Amtrak Acela Express
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Boston South Station Amtrak to New York Penn Station
Ave. Duration
3 h 45 min
Frequency
Hourly
Estimated price
$75 - $160
Website
amtrak.com
Coach
$75 - $160
Business Class
$110 - $200
First Class
$291
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New York Penn Station to Florence Amtrak
Ave. Duration
11 h 50 min
Frequency
4 times a day
Estimated price
$90 - $260
Website
amtrak.com
Coach Seat
$90 - $140
Flexi Coach Seat
$160 - $230
Business Coach Seat
$180 - $260
Room
$370 - $550
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Wells to Boston, Ma
Ave. Duration
1 h 35 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$24 - $35
Bus from Portland, Me to Boston, Ma
Ave. Duration
2 h 10 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Bus from Boston, Ma to New York, Ny
Ave. Duration
4 h 20 min
Frequency
Hourly
Estimated price
$25 - $65
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $65
Bus from New York, Ny to Fayetteville, Nc
Ave. Duration
13 h 45 min
Frequency
Hourly
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1 h 35 min
Frequency
Every 30 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35
Concord Coach Lines
Peter Pan Bus Lines
Phone
1-800-343-9999
Email
dveronesi@peterpanbus.com
Website
peterpanbus.com
Bus from Boston, MA - South Station to New York City, NY - Port Authority Bus Terminal
Ave. Duration
4 h 20 min
Frequency
Every 4 hours
Estimated price
$21 - $40
Website
peterpanbus.com

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Questions & Answers

The distance between Maine and South Carolina is 1660 km. The road distance is 1523 km.

The cheapest way to get from Maine to South Carolina is to drive which costs $90 - $140 and takes 16 h 5 min.

The quickest way to get from Maine to South Carolina is to fly which takes 4 h 5 min and costs $220 - $750.

No, there is no direct bus from Maine to South Carolina. However, there are services departing from Congress St + 389 Congress St and arriving at Florence, Sc via Portland, Me, Boston, Ma, New York, Ny and Fayetteville, Nc. The journey, including transfers, takes approximately 23 h 20 min.

It takes approximately 4 h 5 min to get from Maine to South Carolina, including transfers.