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How to get fromMadrid to Sienaby plane, train, train (Renfe, Ouigo, Trenitalia), bus or car

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There are 8 ways to get from Madrid to Siena by plane, train, train (Renfe, Ouigo, Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Florence Peretola Airport (FLR)plane plane MAD - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 13m
    €66–166

  2. Train

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    3. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    19h 44m
    €168–430

  3. Train, bus

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    2. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    20h 19m
    €129–205

  4. Drive 1,677 km

    1. Drive from Madrid to Sienacar car 1,677 km
    17h 15m
    €258–373

  5. Fly to Pisa International Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Pisa International Airport (PSA)plane plane MAD - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    7h
    €78–213

  6. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MAD - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 59m
    €73–244

  7. Bus

    1. Take the bus from Madrid, Avenida de América to Barcelona, Estació d'Autobusos Nordbus bus
    2. Take the bus from Barcelona - North Bus Station to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    27h 4m
    €89–193

  8. Bus, train

    1. Take the bus from Madrid Mendez Alvaro Estacion Sur to Turin Corso Vittorio Emanuele IIbus bus
    2. Take the train from Torino Porta Susa to Florence Santa Maria Novellatrain train
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    34h 27m

Madrid to Siena by train

Calendar7Weekly Trains
Duration19h 44mAverage Duration
Ticket€168Cheapest Price
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Questions & Answers

What companies run services between Madrid, Spain and Siena, Italy?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Siena via Barcelona-Sants, Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 19h 44m. Alternatively, you can take a bus from Madrid, Avenida de América to Siena via Barcelona - North Bus Station and Florence Villa Constanza Bus Station in around 27h 4m.

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