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There are 10 ways to get from Madrid to Sicily by plane, train, ferry, bus, car or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Palermo

  1. Fly from Madrid (MAD) to Palermo (PMO)

Cheapest option

Fly to Catania

  1. Fly from Madrid (MAD) to Catania (CTA)

8 alternative options

Fly to Comiso

  1. Fly from Madrid (MAD) to Comiso (CIY)

Fly to Trapani

  1. Fly from Madrid (MAD) to Trapani (TPS)

Train, ferry

  1. Take the train from Madrid-Puerta De Atocha to Barcelona-Sants
  2. Take the ferry from Barcellona to Civitavecchia
  3. Take the ferry from Civitavecchia to Palermo

Train, bus, ferry

  1. Take the train from Madrid-Puerta De Atocha to Marseille St Charles
  2. Take the bus from Marseille to Genoa
  3. Take the ferry from Genoa to Palermo

Train, bus

  1. Take the train from Madrid-Puerta De Atocha to Barcelona-Sants
  2. Take the train from Barcelona-Sants to Girona
  3. Take the bus from Gerona/Girona to Verona
  4. Take the train from Verona Porta Nuova to Roma Termini
  5. Take the train from Roma Termini to Palermo Centrale

Bus

  1. Take the bus from Madrid to Turin
  2. Take the bus from Turin to Palermo

Bus via Milan

  1. Take the bus from Madrid Mendez Alvaro Estacion Sur to Milan Lampugnano M1
  2. Take the bus from Milan San Donato Bus Station to Palermo Via Tommaso Fazello

Drive, car ferry

  1. Drive from Madrid to Marseille
  2. Take the car ferry from Marseille to Bejaia
  3. Drive from Bejaia to Tunis
  4. Take the car ferry from Tunis to Palermo

Madrid to Sicily by train, taxi, ferry, walk and bus

The journey time between Madrid and Sicily is around 37h 57m and covers a distance of around 1900 km. This includes an average layover time of around 2h 46m. Operated by Renfe AVE, Renfe SNCF, Renfe Viajeros and others, the Madrid to Sicily service departs from Madrid-Puerta De Atocha and arrives in Leonardo Da Vinci - Galilei. Typically only one service runs weekly, although weekend and holiday schedules can vary so check in advance.

1 Weekly Services
37h 57m Average Duration
€191 Cheapest Price
See schedules
Spain → Italy
Unrestricted

Travel safe during COVID-19

International entry into Italy from Spain

  • Entry is unrestricted for citizens and permanent residents of Spain
Show more details
Allowed for: All visitors

Restricted for: There are no current restrictions

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Conditions of entry into Italy from Spain

  • There are no current restrictions
This applies to arrivals from all countries, with no exceptions

Rules to follow in Italy

1.5m

Mandatory

Mandatory

Considerations leaving from Spain

There are no current restrictions

Frequently Asked Questions


Yes, entry into Italy is currently allowed from Spain.

Explore travel options

Domestic travel is not restricted, but some conditions may apply

  • Face masks are mandatory
  • There is a social distancing requirement of 1.5 metres
  • FFP2 masks are required on all public transport
  • Observe COVID-19 safety rules

Explore travel options

The national COVID-19 helpline number in Sicily is 1500.

Wearing a face mask on public transport in Sicily is mandatory.

The social distance requirement in Sicily is 1.5 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 1500.

No, returning to Spain from Italy is currently allowed.

See options for return travel.

Last updated: 3 Oct 2022
Exceptions may apply, for full details: European Union.

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Madrid to Sicily is to fly which costs €50 - €110 and takes 8h 29m.

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The quickest way to get from Madrid to Sicily is to fly which costs €40 - €230 and takes 6h.

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No, there is no direct bus from Madrid to Sicily. However, there are services departing from Madrid and arriving at Piazza Boiardo via Turin and Stazione Centrale - Pensilina Esterna. The journey, including transfers, takes approximately 2 days 1h.

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It is approximately 1572 km to get from Madrid to Sicily.

The best way to get from Madrid to Sicily without a car is to train and ferry which takes 37h 57m and costs €190 - €320.

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It takes approximately 6h 2m to get from Madrid to Sicily, including transfers.

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Madrid to Sicily bus services, operated by ALSA, depart from Madrid station.

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The best way to get from Madrid to Sicily is to fly which takes 6h 2m and costs €50 - €240. Alternatively, you can bus, which costs €190 - €260 and takes 2 days 1h.

Mode details

The quickest flight from Madrid Airport to Palermo Airport is the direct flight which takes 2h 25m.

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Madrid to Sicily bus services, operated by FlixBus, arrive at Palermo station.

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Map of how to get from Madrid to Sicily.
Launch map view
  • Distance: 1571.9 km
  • Duration: 6h 2m

What companies run services between Madrid, Spain and Sicily, Italy?

Ryanair, Alitalia and two other airlines fly from Madrid to Palermo 5 times a day. Alternatively, you can take a bus from Madrid to Palermo via Turin, Palermo, and Stazione Centrale - Pensilina Esterna in around 2 days 1h.

Airlines
Ryanair
Website
ryanair.com
Flights from Madrid to Palermo
Ave. Duration
2h 25m
When
Tuesday, Thursday and Saturday
Estimated price
€40 - €230
Flights from Madrid to Palermo via Pisa
Ave. Duration
4h 15m
When
Friday
Estimated price
€40 - €230
Flights from Madrid to Palermo via Rome
Ave. Duration
4h 42m
When
Thursday and Sunday
Estimated price
€40 - €230
Flights from Madrid to Palermo via Bologna
Ave. Duration
4h 40m
When
Thursday and Friday
Estimated price
€40 - €230
Flights from Madrid to Palermo via Milan Bergamo
Ave. Duration
4h 40m
When
Tuesday
Estimated price
€40 - €230
Flights from Madrid to Palermo via Marseille
Ave. Duration
5h 50m
When
Monday, Wednesday and Friday
Estimated price
€40 - €230
Flights from Madrid to Palermo via Turin
Ave. Duration
5h 50m
When
Saturday
Estimated price
€40 - €230
Flights from Madrid to Catania
Ave. Duration
2h 40m
When
Wednesday, Friday and Sunday
Estimated price
€30 - €330
Flights from Madrid to Catania via Bologna
Ave. Duration
4h 40m
When
Monday and Thursday
Estimated price
€30 - €330
Flights from Madrid to Catania via Rome
Ave. Duration
5h 5m
When
Tuesday, Friday, Saturday and Sunday
Estimated price
€30 - €330
Flights from Madrid to Catania via Turin
Ave. Duration
5h 5m
When
Monday and Wednesday
Estimated price
€30 - €330
Flights from Madrid to Catania via Milan Malpensa
Ave. Duration
5h 5m
When
Thursday
Estimated price
€30 - €330
Flights from Madrid to Catania via Bari
Ave. Duration
5h 5m
When
Tuesday
Estimated price
€30 - €330
Flights from Madrid to Catania via Marseille
Ave. Duration
5h 15m
When
Tuesday, Wednesday, Thursday and Friday
Estimated price
€30 - €330
Flights from Madrid to Catania via Alghero
Ave. Duration
5h 20m
When
Saturday
Estimated price
€30 - €330
Flights from Madrid to Catania via Milan Bergamo
Ave. Duration
5h 50m
When
Thursday
Estimated price
€30 - €330
Flights from Madrid to Catania via Charleroi
Ave. Duration
5h 55m
When
Tuesday and Saturday
Estimated price
€30 - €330
Flights from Madrid to Comiso via Milan Malpensa
Ave. Duration
5h 40m
When
Tuesday, Wednesday, Friday, Saturday and Sunday
Estimated price
€75 - €270
Flights from Madrid to Comiso via Milan Bergamo
Ave. Duration
6h 20m
When
Wednesday
Estimated price
€55 - €110
Flights from Madrid to Comiso via Rome
Ave. Duration
6h 30m
When
Monday, Thursday and Saturday
Estimated price
€70 - €240
Flights from Madrid to Comiso via Ibiza, Rome
Ave. Duration
6h 30m
When
Monday and Thursday
Estimated price
€55 - €110
Flights from Madrid to Trapani via Malta
Ave. Duration
7h 20m
When
Wednesday
Estimated price
€40 - €100
Flights from Madrid to Trapani via Bologna
Ave. Duration
7h 17m
When
Monday and Friday
Estimated price
€75 - €300
Flights from Madrid to Trapani via Rome
Ave. Duration
9h 25m
When
Thursday
Estimated price
€40 - €100
Flights from Madrid to Trapani via Milan Bergamo
Ave. Duration
9h 35m
When
Monday and Wednesday
Estimated price
€40 - €100
Flights from Madrid to Trapani via Toulouse
Ave. Duration
4h 30m
When
Monday and Friday
Estimated price
€40 - €100
Flights from Madrid to Trapani via London Stansted
Ave. Duration
6h 30m
When
Monday
Estimated price
€40 - €100
Alitalia
Website
alitalia.com
Flights from Madrid to Palermo via Rome
Ave. Duration
4h 55m
When
Every day
Estimated price
€60 - €370
Flights from Madrid to Catania via Rome
Ave. Duration
5h 5m
When
Every day
Estimated price
€60 - €430
easyJet
Website
easyjet.com
Flights from Madrid to Palermo via Geneva
Ave. Duration
5h 15m
When
Saturday
Estimated price
€60 - €350
Iberia
Website
iberia.com
Flights from Madrid to Catania
Ave. Duration
2h 45m
When
Sunday
Estimated price
€130 - €490
Transavia France
Website
transavia.com
Flights from Madrid to Catania via Paris Orly
Ave. Duration
6h
When
Friday
Estimated price
€110 - €600
Train operators
Renfe AVE
Rome2rio's guide to Renfe AVE
Contact Details
Phone
+34 91 232 03 20
Email
comunicacion@renfe.es
Website
renfe.com
Train from Madrid-Puerta De Atocha to Barcelona-Sants
Ave. Duration
2h 30m
Frequency
Hourly
Estimated price
€60 - €120
Website
Renfe AVE
Promo
€60 - €80
Promo+
€68 - €73
Flexible
€90 - €120
Train from Barcelona-Sants to Girona
Ave. Duration
38 min
Frequency
5 times a day
Estimated price
€9 - €35
Website
Renfe AVE
Promo
€9 - €13
Promo+
€14 - €16
Flexible
€24 - €35
Renfe SNCF
Phone
+34 902 320 320
Email
comunicacion@renfe.es
Website
renfe-sncf.com
Train from Madrid-Puerta De Atocha to Barcelona-Sants
Ave. Duration
2h 57m
Frequency
Once daily
Estimated price
€55 - €85
Website
renfe-sncf.com
Train from Madrid-Puerta De Atocha to Marseille St Charles
Ave. Duration
8h 1m
Frequency
Once daily
Estimated price
€85 - €130
Website
renfe-sncf.com
Train from Barcelona-Sants to Girona
Ave. Duration
38 min
Frequency
3 times a day
Estimated price
€30 - €45
Website
renfe-sncf.com
Renfe Viajeros

Spain's excellent and extensive rail system connects cities across Spain and into neighbouring countries. Renfe's high-speed AVE trains can reach speeds of up to 350km/h, making travel between major cities very efficient. All medium- and long-distance trains require a seat reservation; ticket sales for these trains usually open 30-60 days before travel. Most Renfe trains have two classes: Turista (2nd class) and Preferente (1st class), although some AVE trains offer Turista Plus. There is free WiFi for Preferente passengers and for those with a +Renfe loyalty card.

Rome2rio's guide to Renfe Viajeros
Contact Details
Phone
+34 91 232 03 20
Email
comunicacion@renfe.es
Website
renfe.com
Train from Barcelona-Sants to Girona
Ave. Duration
38 min
Frequency
Hourly
Estimated price
€10 - €13
Website
Renfe Viajeros
Trenitalia Frecce

Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Verona Porta Nuova to Roma Termini
Ave. Duration
3h 18m
Frequency
Every 4 hours
Estimated price
€30 - €110
Website
Trenitalia Frecce
Super Economy
€30 - €50
Base Standard
€60 - €85
Base Premium
€75 - €110
ItaloTreno

Private train company Italotreno operates high-speed trains in Italy on the same tracks as Trenitalia. The routes service 21 stations across the country, including popular routes Milan-Florence, Rome-Venice and Bologna-Naples. Choose from four classes of service, all with free Wi-Fi: Smart, Comfort, Prima and Club Executive. Italo also operates Italobus – an integrated train-bus service that takes passengers from the main train stations to other Italian cities.

Contact Details
Phone
+39 060708
Website
italotreno.it
Train from Verona Porta Nuova to Roma Termini
Ave. Duration
3h 13m
Frequency
3 times a day
Estimated price
€27 - €80
Website
Italo Treno
Smart Economy
€29 - €45
Smart Low Cost
€27 - €40
Smart Flex
€55 - €80
Trenitalia Intercity

Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Palermo Centrale
Ave. Duration
11h 59m
Frequency
Once daily
Estimated price
€50 - €75
Website
Trenitalia Intercity
2nd Class
€50 - €75
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 30 300 137 300
Email
service@flixbus.com
Website
flixbus.de
Bus from Marseille to Genoa
Ave. Duration
6h 25m
Frequency
Every 3 hours
Estimated price
€20 - €25
Website
flixbus.co.uk
Bus from Turin to Palermo
Ave. Duration
24h 25m
Frequency
Twice daily
Estimated price
€75 - €95
Website
flixbus.co.uk
Frequently asked questions
Is there Wi-Fi on FlixBus?
Yes - FlixBus offers free Wi-Fi
Are there power outlets on FlixBus?
Yes
Does FlixBus offer meals or snacks?
Yes - snacks and drinks may be purchased from the driver. Please note, this is not available on all services.
For more information, please visit this page
ALSA

A Spanish subsidiary of National Express, ALSA provides bus and coach services across Spain and neighbouring countries including Portugal, France, Germany, the Netherlands, Italy, Poland and Malta. Founded in 1923, ALSA values service and the customer experience. Buses are equipped with communal TV screens showing movies, individual behind-seat screens, ALSA radio, app for books and music, and free WiFi. ALSA services are accessible to people with disabilities, and guide dogs are welcome on all journeys. There are three types of tickets on offer (Frequent Traveller Pass, Share Pass and ALSA Pass), along with discounts for senior citizens, students and children.

Contact Details
Phone
+34 902 42 22 42
Email
alsa@alsa.es
Website
alsa.es
Bus from Gerona/Girona to Verona
Ave. Duration
18h 15m
Frequency
Once daily
Estimated price
€85 - €120
Website
ALSA
Bus from Madrid to Turin
Ave. Duration
23h
Frequency
Once daily
Estimated price
€120 - €170
Website
ALSA
Union Ivkoni
Phone
02/989 0000
Website
union-ivkoni.com
Bus from Madrid Mendez Alvaro Estacion Sur to Milan Lampugnano M1
Ave. Duration
26h
Frequency
Twice a week
Estimated price
€55 - €80
Website
Union Ivkoni
Autoservizi Salemi Srl
Phone
(+39) 0923 98.11.20
Website
autoservizisalemi.it
Bus from Milan San Donato Bus Station to Palermo Via Tommaso Fazello
Ave. Duration
21h
Frequency
Once daily
Estimated price
€70 - €110
Schedules at
autoservizisalemi.it
Ferry operators
Grimaldi Lines
Phone
+39.081.496.444
Email
info@grimaldi.napoli.it
Website
grimaldi-lines.com
Ferry from Barcellona to Civitavecchia
Ave. Duration
20h
Frequency
6 times a week
Estimated price
€60 - €95
Website
Grimaldi Lines
Car ferry from Tunis to Palermo
Ave. Duration
10h 30m
Frequency
Twice a week
Estimated price
€23 - €35
Website
Grimaldi Lines
Grandi Navi Veloci
Phone
+39 010 209 4591
Email
booking@gnv.it
Website
gnv.it
Ferry from Civitavecchia to Palermo
Ave. Duration
12h
Frequency
Once a week
Estimated price
€55 - €85
Website
Grandi Navi Veloci
Ferry from Genoa to Palermo
Ave. Duration
21h
Frequency
Once daily
Estimated price
€60 - €140
Website
Grandi Navi Veloci
Algerie Ferries
Phone
+213 (0)21.63.53.76
Email
drc.entmv@algerieferries.dz
Website
algerieferries.dz
Car ferry from Marseille to Bejaia
Ave. Duration
20h
Frequency
Once a week
Estimated price
€255
Website
Algerie Ferries

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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Alitalia, easyJet and Ryanair offer flights from Madrid Airport to Palermo Airport.

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There are 33+ hotels available in Sicily. Prices start at €100 per night.

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