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There are 5 ways to get from Madrid to Santa María de Cayón by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Recommended option

Train

  1. Take the train from Madrid-Chamartin to Santander

4 alternative options

Bus

  1. Take the bus from Madrid to Santander

Drive

  1. Drive from Madrid to Santa María de Cayón

Fly to Santander, bus

  1. Fly from Madrid (MAD) to Santander (SDR)
  2. Take the bus from Santander to Santa Maria De Cayon

Fly to Bilbao, bus

  1. Fly from Madrid (MAD) to Bilbao (BIO)
  2. Take the bus from Bilbao to Santander
  3. Take the bus from Santander to Santa Maria De Cayon

Madrid to Santa María de Cayón by subway, train and bus

20 Weekly Services
7h 8m Average Duration
€40 Cheapest Price
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Questions & Answers

The most affordable way to get from Madrid to Santa María de Cayón is to train, which costs €35 - €60 and takes 7h 8m.

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The quickest way to get from Madrid to Santa María de Cayón is to drive which costs €75 - €110 and takes 4h 18m.

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No, there is no direct bus from Madrid to Santa María de Cayón. However, there are services departing from Madrid and arriving at Santa Maria De Cayon via Santander. The journey, including transfers, takes approximately 7h 20m.

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The distance between Madrid and Santa María de Cayón is 322 km. The road distance is 443.3 km.

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The best way to get from Madrid to Santa María de Cayón without a car is to train which takes 7h 8m and costs €35 - €60.

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It takes approximately 7h 8m to get from Madrid to Santa María de Cayón, including transfers.

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Madrid to Santa María de Cayón bus services, operated by ALSA, depart from Madrid station.

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The best way to get from Madrid to Santa María de Cayón is to train which takes 7h 8m and costs €35 - €60. Alternatively, you can bus, which costs €65 - €110 and takes 7h 20m.

Mode details

The quickest flight from Madrid Airport to Santander Airport is the direct flight which takes 1h 5m.

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Madrid to Santa María de Cayón bus services, operated by ALSA, arrive at Santander station.

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Map of how to get from Madrid to Santa María de Cayón.
Launch map view
  • Distance: 322 km
  • Duration: 7h 8m

What companies run services between Madrid, Spain and Santa María de Cayón, Spain?

Renfe Viajeros operates a train from Madrid-Chamartin to Santander 3 times a day. Tickets cost €35 - €50 and the journey takes 4h 14m. Alternatively, ALSA operates a bus from Madrid to Santander every 4 hours. Tickets cost €65 - €95 and the journey takes 5h 45m.

Airlines
Iberia
Website
iberia.com
Flights from Madrid to Santander
Ave. Duration
1h 8m
When
Every day
Estimated price
€40 - €320
Flights from Madrid to Bilbao
Ave. Duration
1h 2m
When
Every day
Estimated price
€35 - €250
Air Europa
Website
aireuropa.com
Flights from Madrid to Bilbao
Ave. Duration
1h
When
Every day
Estimated price
€30 - €180
Train operators
Bus operators
ALSA
Phone
+34 910 207 007
Email
alsa@alsa.es
Website
alsa.es
Bus from Madrid to Santander
Ave. Duration
5h 45m
Frequency
Every 4 hours
Estimated price
€65 - €95
Website
https://www.alsa.com/en/web/bus/home
Bus from Santander to Santa Maria De Cayon
Ave. Duration
35 min
Frequency
Every 4 hours
Estimated price
€3 - €6
Website
https://www.alsa.com/en/web/bus/home
Bus from Bilbao to Santander
Ave. Duration
1h 20m
Frequency
Hourly
Estimated price
€14 - €22
Website
https://www.alsa.com/en/web/bus/home
FlixBus
Rome2Rio's guide to FlixBus
Contact Details
Phone
+49 30 300 137 300
Email
service@flixbus.com
Website
flixbus.de
Bus from Bilbao to Santander
Ave. Duration
1h 10m
Frequency
Once daily
Estimated price
€10 - €14
Website
https://www.flixbus.co.uk
Book at
https://shop.global.flixbus.com/
Frequently asked questions
Is there Wi-Fi on FlixBus?
Yes - FlixBus offers free Wi-Fi
Are there power outlets on FlixBus?
Yes
Does FlixBus offer meals or snacks?
Yes - snacks and drinks may be purchased from the driver. Please note, this is not available on all services.
For more information, please visit this page

Want to know more about travelling around Spain

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Madrid to Santa María de Cayón is 443 km. It takes approximately 4h 18m to drive from Madrid to Santa María de Cayón.

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Iberia offers flights from Madrid Airport to Santander Airport.

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Book your Madrid to Santa María de Cayón bus tickets online with Omio and Busbud.

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There are 1666+ hotels available in Santa María de Cayón. Prices start at €87 per night.

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The best way to get from Madrid to Madrid Airport is to train which takes 26 min and costs €2 - €3.

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