There are 9 ways to get from Madrid to Mendrisio by plane, train, train (Renfe, Ouigo, Trenitalia), bus, car, or train (Renfe, TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Milano Malpensa Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milano Malpensa Airport (MXP)plane MAD - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 52mCHF 30–138Train via Barcelona
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mendrisiotrain
16h 27mCHF 114–222Bus
- Take the bus from Madrid - South Station to Lyon - Perrache Bus Stationbus
- Take the bus from Lyon - Perrache Bus Station to Turin - Vittorio Emanuele Bus Stationbus
- Take the bus from Turin to Mendrisiobus
26h 29mCHF 102–146Drive 1,495.5 km
- Drive from Madrid to Mendrisiocar 1,495.5 km
16h 38mCHF 232–335Fly to Milan Linate Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milan Linate Airport (LIN)plane MAD - LIN
- Take the train from Monza to Mendrisiotrain
6h 40mCHF 62–180Fly to Il Caravaggio International Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Il Caravaggio International Airport (BGY)plane MAD - BGY
- Take the train from Milano Centrale to Mendrisiotrain
6h 58mCHF 80–262Fly to Zurich Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Zurich Airport (ZRH)plane MAD - ZRH
- Take the train from Zürich HB to Luganotrain
7h 29mCHF 111–302Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the train from Marseille St Charles to Nice Villetrain Tgv
- Take the train from Ventimiglia to Gallaratetrain
- Take the train from Gallarate to Mendrisiotrain S50 / ...
21h 35mCHF 143–228Bus, train
- Take the bus from Estación Sur de Autobuses to Geneva - Bus stationbus
- Take the train from Genève to Locarnotrain Ic
- Take the train from Locarno to Mendrisiotrain S
28h 51mCHF 235–459
Madrid to Mendrisio by train
Questions & Answers
The cheapest way to get from Madrid to Mendrisio is to fly and train which costs SFr 29 - SFr 140 and takes 5h 52m.
The fastest way to get from Madrid to Mendrisio is to fly and train which takes 5h 52m and costs SFr 29 - SFr 140.
No, there is no direct bus from Madrid station to Mendrisio. However, there are services departing from Madrid - South Station and arriving at Mendrisio via Lyon - Perrache Bus Station and Turin. The journey, including transfers, takes approximately 26h 29m.
No, there is no direct train from Madrid to Mendrisio. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at Mendrisio via Barcelona-Sants, Lyon Part Dieu and Milano Centrale. The journey, including transfers, takes approximately 16h 27m.
The distance between Madrid and Mendrisio is 1218 km. The road distance is 1495.5 km.
The best way to get from Madrid to Mendrisio without a car is to train via Barcelona which takes 16h 27m and costs SFr 110 - SFr 230.
It takes approximately 5h 52m to get from Madrid to Mendrisio, including transfers.
Madrid to Mendrisio bus services, operated by BlaBlaCar Bus, depart from Madrid - South Station.
Madrid to Mendrisio train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Mendrisio is to train via Barcelona which takes 16h 27m and costs SFr 110 - SFr 230. Alternatively, you can bus, which costs SFr 100 - SFr 150 and takes 26h 29m.
What companies run services between Madrid, Spain and Mendrisio, Switzerland?
You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Mendrisio via Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 16h 27m. Alternatively, you can take a bus from Madrid - South Station to Mendrisio via Lyon - Perrache Bus Station and Turin in around 26h 29m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 29–95
Flights from Adolfo Suárez Madrid–Barajas Airport to Il Caravaggio International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- CHF 45–160
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 27–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- CHF 50–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- CHF 45–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport via Barcelona
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- CHF 90–200
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- CHF 27–140
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- CHF 50–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- CHF 45–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport via Barcelona
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- CHF 90–200
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- CHF 45–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- CHF 40–150
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milano Malpensa Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- CHF 21–100
- Website
- swiss.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Zurich Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- CHF 60–220
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport via Palma Mallorca
- Ave. Duration
- 5h
- When
- Saturday
- Estimated price
- CHF 60–160
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 24–45
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 24–45
- Website
- https://www.sbb.ch/en
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 55–110
- Website
- https://www.sbb.ch/en
Train from Gallarate to Mendrisio
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- CHF 20–35
- Website
- https://www.sbb.ch/en
Train from Genève to Locarno
- Ave. Duration
- 5h 3m
- Frequency
- Once a week
- Estimated price
- CHF 120–230
- Website
- https://www.sbb.ch/en
Train from Locarno to Mendrisio
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- CHF 15–27
- Website
- https://www.sbb.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–3
- Website
- https://www.trenord.it/en/
Train from Gallarate to Mendrisio
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- CHF 3–5
- Website
- https://www.trenord.it/en/
Train from Locarno to Mendrisio
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- https://www.trenord.it/en/
Rome2Rio's guide to Renfe AVE
Contact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- CHF 45–70
- Website
- https://www.renfe.com/es/en
- Básico
- CHF 45–70
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 20m
- Frequency
- Hourly
- Estimated price
- CHF 24–80
- Website
- https://iryo.eu/en/home
- Inicial
- CHF 24–80
- Phone
- +34 910 780 990
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 28m
- Frequency
- 5 times a day
- Estimated price
- CHF 22–70
- Website
- https://www.ouigo.com/es/en
Rome2Rio's guide to Renfe Viajeros
Contact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- CHF 45–60
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- CHF 45–65
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- CHF 80–120
- Website
- https://www.renfe.com/es/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- CHF 22–35
- Website
- https://www.trenitalia.com/en.html
Train from Ventimiglia to Gallarate
- Ave. Duration
- 5h 52m
- Frequency
- Twice a week
- Estimated price
- CHF 16–25
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Marseille St Charles to Nice Ville
- Ave. Duration
- 2h 36m
- Frequency
- Every 4 hours
- Estimated price
- CHF 35–75
- Website
- https://www.sncf-connect.com/en-en
- 2nd Class
- CHF 35–50
- 1st Class
- CHF 55–75
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Madrid - South Station to Lyon - Perrache Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- Twice daily
- Estimated price
- CHF 65–95
- Website
- https://www.blablacar.co.uk/bus
Bus from Lyon - Perrache Bus Station to Turin - Vittorio Emanuele Bus Station
- Ave. Duration
- 4h 40m
- Frequency
- 4 times a day
- Estimated price
- CHF 24–35
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Turin to Mendrisio
- Ave. Duration
- 3h 4m
- Frequency
- Twice daily
- Estimated price
- CHF 10–18
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Estación Sur de Autobuses to Geneva - Bus station
- Ave. Duration
- 21h 30m
- Frequency
- Twice a week
- Estimated price
- CHF 110–230
- Website
- https://www.alsa.com/en/
Want to know more about travelling around Switzerland
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More Questions & Answers
Madrid to Mendrisio bus services, operated by BlaBlaCar Bus, arrive at Lyon - Perrache Bus Station.
Madrid to Mendrisio train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between Madrid to Mendrisio is 1496 km. It takes approximately 16h 38m to drive from Madrid to Mendrisio.
There are 5091+ hotels available in Mendrisio.











































