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How to get fromMadrid to Issoireby train (Renfe), bus, car, plane, train (Renfe, Ouigo) or train

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There are 8 ways to get from Madrid to Issoire by train (Renfe), bus, car, plane, train (Renfe, Ouigo), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Nimestrain train 9725
    2. Take the train from Nimes to Issoiretrain train Ter
    12h 36m
    €122–228
  2. Bus

    cheapest
    1. Take the bus from Madrid Mendez Alvaro Estacion Sur to Clermont Ferrandbus bus Union Ivkoni - Unibus 3419 / ...
    17h 25m
    €53–75
  3. Drive 1,012.6 km

    1. Drive from Madrid to Issoirecar car 1,012.6 km
    11h 40m
    €160–231
  4. Fly to Clermont-Ferrand Auvergne Airport

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Clermont-Ferrand Auvergne Airport (CFE)plane plane MAD - CFE
    8h 12m
    €106–348
  5. Train via Barcelona

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    3. Take the train from Lyon Part Dieu to Clermont Ferrandtrain train Ter
    13h 21m
    €114–284
  6. Bus via Valladolid

    1. Take the bus from Estación Sur de Autobuses to Valladolidbus bus Alsa
    2. Take the bus from Valladolid to Clermont-Ferrand - Bus Stationbus bus BlaBlaCar Bus
    18h 9m
    €73–152
  7. Fly to Lyon–Saint Exupéry Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Lyon–Saint Exupéry Airport (LYS)plane plane MAD - LYS
    2. Take the train from Lyon Part Dieu to Clermont Ferrandtrain train
    9h 24m
    €99–263
  8. Fly to Toulouse-Blagnac Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Toulouse-Blagnac Airport (TLS)plane plane MAD - TLS
    2. Take the train from Toulouse Matabiau to Issoiretrain train
    10h 39m
    €101–331

Madrid to Issoire by train

Calendar7Weekly Trains
Duration12h 36mAverage Duration
Ticket€122Cheapest Price
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Questions & Answers

What companies run services between Madrid, Spain and Issoire, Auvergne-Rhône-Alpes, France?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Issoire via Nimes in around 12h 36m. Alternatively, Union Ivkoni operates a bus from Madrid Mendez Alvaro Estacion Sur to Clermont Ferrand 3 times a week. Tickets cost €45–65 and the journey takes 15h 45m.

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