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How to get fromMadrid to Hesseby plane, train (Renfe, Ouigo, TGV), bus, car, train, train (Renfe, Ouigo) or train (Renfe, TGV)

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There are 8 ways to get from Madrid to Hesse by plane, train (Renfe, Ouigo, TGV), bus, car, train, train (Renfe, Ouigo), or train (Renfe, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Frankfurt

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Frankfurt (FRA)plane plane MAD - FRA
    5h 17m
    €95–253
  2. Bus via Paris

    cheapest
    1. Take the bus from Madrid - South Station to Paris - Bercy-Seine Bus Stationbus bus BlaBlaCar Bus
    2. Take the bus from Paris - Bercy-Seine Bus Station to Frankfurt - Main Bus Stationbus bus BlaBlaCar Bus
    25h 52m
    €62–216
  3. Train via Paris

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Paris Gare De Lyontrain train Tgv
    3. Take the train from Paris Est to Frankfurt(Main)Hbftrain train Ice
    15h 43m
    €136–540
  4. Drive 1,772.3 km

    1. Drive from Madrid to Frankfurt am Maincar car 1,772.3 km
    17h 33m
    €277–399
  5. Fly to Düsseldorf International Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Düsseldorf International Airport (DUS)plane plane MAD - DUS
    2. Take the train from Düsseldorf Hbf to Frankfurttrain train
    7h 11m
    €118–362
  6. Train

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Lyon Part Dieutrain train
    3. Take the train from Lyon Part Dieu to Frankfurttrain train 84
    15h 48m
    €190–383
  7. Train #2

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgvtrain train 9725
    2. Take the train from Avignon Tgv to Frankfurt(Main)Hbftrain train Tgv
    15h 54m
    €155–380
  8. Bus

    1. Take the bus from Estación Sur de Autobuses to Valladolidbus bus Alsa
    2. Take the bus from Valladolid to Frankfurt central train stationbus bus FlixBus N1151
    30h 16m
    €143–232

Madrid to Hesse by train and foot

Calendar14Weekly Services
Duration15h 43mAverage Duration
Ticket€136Cheapest Price
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Questions & Answers

What companies run services between Madrid, Spain and Hesse, Germany?

Iberia, Air Europa, and Lufthansa fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Frankfurt (FRA) every 4 hours. Alternatively, you can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Frankfurt via Barcelona-Sants, Paris Gare de Lyon, Paris Gare Du Nord, Paris Est, Frankfurt(Main)Hbf, and Frankfurt in around 15h 43m.

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