There are 9 ways to get from Madrid to Comiso by plane, train, bus, ferry, car ferry, night train, busferry, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Vincenzo Magliocco Airport
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Vincenzo Magliocco Airport (CIY)plane MAD - CIY
7h 18m€112–285Fly to Catania–Fontanarossa Airport, bus
cheapest- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Catania–Fontanarossa Airport (CTA)plane MAD - CTA
- Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus
9h 21m€66–217Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the bus from Barcelona - North Bus Station to Roma, Autostazione Tiburtinabus
- Take the train from Roma Termini to Siracusatrain Ic
- Take the train from Siracusa to Comisotrain Re
41h 11m€196–412Train, ferry
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the ferry from Port of Civitavecchia to Port of Palermo Termini Imereseferry
- Take the train from Termini Imerese to Caltanissetta Xirbitrain Re
- Take the train from Caltanissetta Xirbi to Comisotrain
42h 50m€139–283Train, car ferry, night train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the car ferry from Port de Barcelona to Port of Genoacarferry
- Take the night train from Genova P.Za Principe to Siracusanighttrain Ini
- Take the train from Siracusa to Comisotrain Re
2d€197–382Fly to Malta International Airport, bus and ferry, taxi
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Malta International Airport (MLA)plane MAD - MLA
- Take the busferry from Valletta to Pozzallobusferry
- Take the taxi from Pozzallo to Comisotaxi
9h 39m€225–344Fly to Palermo Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Palermo Airport (PMO)plane MAD - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbitrain
- Take the train from Caltanissetta Xirbi to Comisotrain
11h 48m€79–226Bus
- Take the bus from Madrid, Avenida de América to Barcelona, Estació d'Autobusos Nordbus
- Take the bus from Barcelona - North Bus Station to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Gela Bus Stationbus
43h 20m€165–270Bus via Turin
- Take the bus from Madrid to Lyonbus
- Take the bus from Lyon to Turinbus 480 / ...
- Take the bus from Turin to Catania Airportbus
- Take the bus from Catania Airport to Comisobus
2d 2h€200–349
Madrid to Comiso by train, foot, and bus
Questions & Answers
The cheapest way to get from Madrid to Comiso is to fly and bus which costs €65 - €220 and takes 9h 21m.
The fastest way to get from Madrid to Comiso is to fly which takes 7h 18m and costs €110 - €290.
No, there is no direct bus from Madrid to Comiso. However, there are services departing from Madrid, Avenida de América and arriving at Comiso via Barcelona - North Bus Station, Roma, Autostazione Tiburtina and Gela. The journey, including transfers, takes approximately 43h 20m.
The distance between Madrid and Comiso is 1638 km.
The best way to get from Madrid to Comiso without a car is to train and bus which takes 41h 11m and costs €190 - €420.
It takes approximately 7h 18m to get from Madrid to Comiso, including transfers.
Madrid to Comiso bus services, operated by FlixBus, depart from Madrid station.
The best way to get from Madrid to Comiso is to fly which takes 7h 18m and costs €110 - €290. Alternatively, you can bus, which costs €160 - €270 and takes 43h 20m.
Madrid to Comiso bus services, operated by FlixBus, arrive at Lyon station.
Book your Madrid to Comiso bus tickets online with FlixBus.
What companies run services between Madrid, Spain and Comiso, Italy?
Ulendo Airlink, ITA Airways, and five other airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Vincenzo Magliocco Airport (CIY) 3 times a day. Alternatively, you can take a bus from Madrid, Avenida de América to Comiso via Barcelona - North Bus Station, Roma, Autostazione Tiburtina, and Gela in around 43h 20m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €55–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport via Malta International Airport
- Ave. Duration
- 5h 20m
- When
- Monday, Friday, and Saturday
- Estimated price
- €55–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Malta International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- €35–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Malta International Airport via Palma Mallorca
- Ave. Duration
- 4h 40m
- When
- Sunday
- Estimated price
- €35–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Tuesday to Sunday
- Estimated price
- €45–180
- Website
- flexflight.dk
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- €70–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 5h
- When
- Saturday and Sunday
- Estimated price
- €80–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Bologna
- Ave. Duration
- 6h 5m
- When
- Monday and Friday
- Estimated price
- €60–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Turin
- Ave. Duration
- 8h 5m
- When
- Monday and Friday
- Estimated price
- €140–440
- Website
- aeroitalia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- €70–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 5h
- When
- Saturday and Sunday
- Estimated price
- €80–260
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Bologna
- Ave. Duration
- 6h 5m
- When
- Monday and Friday
- Estimated price
- €60–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Turin
- Ave. Duration
- 8h 5m
- When
- Monday and Friday
- Estimated price
- €140–440
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Sunday
- Estimated price
- €70–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Malta International Airport via Barcelona
- Ave. Duration
- 5h 55m
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- €35–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday and Thursday
- Estimated price
- €65–280
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 50m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €120–220
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Sunday
- Estimated price
- €70–220
Flights from Adolfo Suárez Madrid–Barajas Airport to Malta International Airport via Barcelona
- Ave. Duration
- 5h 55m
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- €35–170
Flights from Adolfo Suárez Madrid–Barajas Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 50m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €120–220
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Tirana
- Ave. Duration
- 9h 10m
- When
- Friday
- Estimated price
- €50–230
- Website
- volotea.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Vincenzo Magliocco Airport via Verona
- Ave. Duration
- 6h 30m
- When
- Friday
- Estimated price
- €60–220
- Website
- airmalta.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Malta International Airport
- Ave. Duration
- 2h 45m
- When
- Monday and Friday
- Estimated price
- €45–170
Rome2Rio's guide to Renfe AVE
Contact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €50–75
- Website
- https://www.renfe.com/es/en
- Básico
- €50–75
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 20m
- Frequency
- Hourly
- Estimated price
- €27–85
- Website
- https://iryo.eu/en/home
- Inicial
- €27–85
- Phone
- +34 910 780 990
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 28m
- Frequency
- 5 times a day
- Estimated price
- €25–80
- Website
- https://www.ouigo.com/es/en
Rome2Rio's guide to Renfe Viajeros
Contact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- €45–65
- Website
- https://www.renfe.com/es/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- Once daily
- Estimated price
- €80–190
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siracusa to Comiso
- Ave. Duration
- 2h 34m
- Frequency
- 3 times a day
- Estimated price
- €9–14
- Website
- https://www.trenitalia.com/en.html
Train from Termini Imerese to Caltanissetta Xirbi
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Caltanissetta Xirbi to Comiso
- Ave. Duration
- 2h 12m
- Frequency
- Twice daily
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
- Phone
- 06 3000
- Website
- trenitalia.com
Night train from Genova P.Za Principe to Siracusa
- Ave. Duration
- 17h 59m
- Frequency
- Once a week
- Estimated price
- €95–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Barcelona - North Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 20h
- Frequency
- Twice daily
- Estimated price
- €80–120
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminal
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €6–9
- Schedules at
- interbus.it
- Phone
- (+356) 22069022
- res@virtuferries.com
- Website
- virtuferries.com
Busferry from Valletta to Pozzallo
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- €73
- Website
- https://www.virtuferries.com/
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Madrid, Avenida de América to Barcelona, Estació d'Autobusos Nord
- Ave. Duration
- 8h 5m
- Frequency
- Every 3 hours
- Estimated price
- €50–100
- Website
- https://www.alsa.com/en/
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Gela Bus Station
- Ave. Duration
- 11h 15m
- Frequency
- Once daily
- Estimated price
- €35–50
- Schedules at
- autoservizisalemi.it
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Madrid to Lyon
- Ave. Duration
- 18h 15m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- https://www.flixbus.co.uk
Bus from Lyon to Turin
- Ave. Duration
- 4h 10m
- Frequency
- Hourly
- Estimated price
- €19–35
- Website
- https://www.flixbus.co.uk
Bus from Turin to Catania Airport
- Ave. Duration
- 21h 35m
- Frequency
- Once daily
- Estimated price
- €90–160
- Website
- https://www.flixbus.co.uk
Bus from Catania Airport to Comiso
- Ave. Duration
- 3h 38m
- Frequency
- Once daily
- Estimated price
- €11–19
- Website
- https://www.flixbus.co.uk
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €40–60
- Website
- https://www.grimaldi-lines.com/en/
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Ferry from Port of Civitavecchia to Port of Palermo Termini Imerese
- Ave. Duration
- 12h
- Frequency
- Twice a week
- Estimated price
- €55–101
- Website
- https://www.gnv.it/en
- Seat
- €55–70
- Cabin
- €98–101
Car ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 20h 45m
- Frequency
- Twice a week
- Estimated price
- €65–140
- Website
- https://www.gnv.it/en
- Seat
- €65–95
- Cabin
- €120–140
- Ave. Duration
- 52 min
- Estimated price
- €80–100
Walk Around Sicily
- Phone
- +39 335 800 4210
- Website
- walkaroundsicily.com
Taxi Modica H24
- Phone
- +39 392 102 7894
- Website
- taximodica.it
Taxi Pozzallo
- Phone
- +3909321846960, +393358004210
- Website
- taxipozzallo.com
Taxi - N.C.C. Autonoleggio Ragusa
- Phone
- +39 333 991 0777
- Website
- iviaggidellisola.com
Radio Taxi Libero
- Phone
- +39 334 100 0344
- Website
- digilander.libero.it
Cisa NCC Taxi
- Phone
- +39 320 673 4244
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