There are 12 ways to get from Madrid to Assisi by plane, train, train (Renfe, Ouigo, TGV, Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Florence Peretola Airport (FLR)plane MAD - FLR
- Take the train from Firenze S.M.N. to Assisitrain
9h 38m€71–217Fly to Fiumicino International Airport, train
cheapest- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Fiumicino International Airport (FCO)plane MAD - FCO
- Take the train from Roma Termini to Folignotrain
9h 57m€46–191Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Perugiatrain Fr
21h 27m€180–466Train, bus
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
22h 20m€144–211Drive 1,808.8 km
- Drive from Madrid to Assisicar 1,808.8 km
18h 2m€285–412Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Bologna Guglielmo Marconi Airport (BLQ)plane MAD - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
10h 24m€70–285Fly to Pisa International Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Pisa International Airport (PSA)plane MAD - PSA
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
10h 58m€85–261Fly to Raffaello Sanzio Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Raffaello Sanzio Airport (AOI)plane MAD - AOI
- Take the train from Jesi to Folignotrain
9h 56m€73–384Fly to Milan Linate Airport, train
- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Milan Linate Airport (LIN)plane MAD - LIN
- Take the train from Milano P.Garibaldi to Perugiatrain
11h 10m€137–332Train, bus via Barcelona
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the bus from Barcelona - North Bus Station to Florence Villa Constanza Bus Stationbus
- Take the train from Firenze S.M.N. to Assisitrain
26h 47m€104–241Bus via Genoa
- Take the bus from Madrid to Genoabus
- Take the bus from Genoa to Florence Villa Constanza Bus Stationbus 510 / ...
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
28h 11m€120–213Bus
- Take the bus from Méndez Álvaro Estación Sur to Padovabus
- Take the bus from Padua to Perugiabus N433 / ...
38h 56m€92–130
Madrid to Assisi by train and bus
Questions & Answers
The cheapest way to get from Madrid to Assisi is to bus which costs €90 - €130 and takes 38h 56m.
The fastest way to get from Madrid to Assisi is to fly and train which takes 9h 38m and costs €70 - €220.
No, there is no direct bus from Madrid to Assisi. However, there are services departing from Madrid and arriving at Assisi via Genoa and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 28h 11m.
The distance between Madrid and Assisi is 1468 km. The road distance is 1808.8 km.
The best way to get from Madrid to Assisi without a car is to train which takes 21h 27m and costs €180 - €470.
It takes approximately 9h 38m to get from Madrid to Assisi, including transfers.
Madrid to Assisi bus services, operated by FlixBus, depart from Madrid station.
The best way to get from Madrid to Assisi is to train which takes 21h 27m and costs €180 - €470. Alternatively, you can bus via Genoa, which costs €120 - €220 and takes 28h 11m.
Madrid to Assisi bus services, operated by FlixBus, arrive at Genoa station.
Yes, the driving distance between Madrid to Assisi is 1809 km. It takes approximately 18h 2m to drive from Madrid to Assisi.
What companies run services between Madrid, Spain and Assisi, Italy?
You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to P.za Matteotti Assisi via Barcelona-Sants, Lyon Part Dieu, Torino Porta Susa, Perugia, and Fontivegge - Perugia in around 21h 27m. Alternatively, you can take a bus from Madrid to Assisi via Genoa and Florence Villa Constanza Bus Station in around 28h 11m.
- Website
- iberia.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- €55–210
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €55–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €45–110
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €60–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Friday
- Estimated price
- €95–200
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €60–160
- Website
- vueling.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- €55–210
Flights from Adolfo Suárez Madrid–Barajas Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €55–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €45–110
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport via Ibiza
- Ave. Duration
- 5h 10m
- When
- Monday
- Estimated price
- €70–190
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €60–160
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Friday
- Estimated price
- €95–200
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €60–160
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- €50–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport via Palma Mallorca
- Ave. Duration
- 4h 25m
- When
- Tuesday and Thursday
- Estimated price
- €50–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €50–150
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €55–180
Flights from Adolfo Suárez Madrid–Barajas Airport to Pisa International Airport via Palma Mallorca
- Ave. Duration
- 5h 15m
- When
- Monday
- Estimated price
- €55–180
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €45–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport via Valencia
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- €45–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Milan Linate Airport via Palma Mallorca
- Ave. Duration
- 5h
- When
- Saturday
- Estimated price
- €65–180
- Website
- aireuropa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €45–130
Flights from Adolfo Suárez Madrid–Barajas Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €85–190
- Website
- flyulendo.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Fiumicino International Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €29–130
- Website
- volotea.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Raffaello Sanzio Airport
- Ave. Duration
- 2h 25m
- When
- Thursday and Sunday
- Estimated price
- €27–240
- Website
- lufthansa.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Raffaello Sanzio Airport via Munich
- Ave. Duration
- 5h 15m
- When
- Monday
- Estimated price
- €110–440
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 33m
- Frequency
- Every 4 hours
- Estimated price
- €11–16
- Website
- https://www.trenitalia.com/en.html
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 52m
- Frequency
- Hourly
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 25m
- Frequency
- Every 30 minutes
- Estimated price
- €6–9
- Website
- https://www.trenitalia.com/en.html
Train from Jesi to Foligno
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- €7–11
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €17–40
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 54m
- Frequency
- 3 times a day
- Estimated price
- €14–35
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Jesi to Foligno
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €10–23
- Website
- https://www.trenitalia.com/en.html
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €50–75
- Website
- https://www.renfe.com/es/en
- Básico
- €50–75
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 17m
- Frequency
- Hourly
- Estimated price
- €27–85
- Website
- https://iryo.eu/en/home
- Inicial
- €27–85
- Phone
- +34 910 780 990
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- 5 times a day
- Estimated price
- €25–80
- Website
- https://www.ouigo.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- Twice daily
- Estimated price
- €45–65
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- €50–75
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- €90–130
- Website
- https://www.renfe.com/es/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 55m
- Frequency
- Once a week
- Estimated price
- €100–180
- Website
- https://www.sncf-connect.com/en-en
- 2nd Class
- €100–140
- 1st Class
- €140–180
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Perugia
- Ave. Duration
- 4h 40m
- Frequency
- 6 times a week
- Estimated price
- €85–170
- Schedules at
- trenitalia.com
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 42m
- Frequency
- Once daily
- Estimated price
- €21–45
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Schedules at
- trenitalia.com
Train from Jesi to Foligno
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €14–29
- Schedules at
- trenitalia.com
Train from Milano P.Garibaldi to Perugia
- Ave. Duration
- 3h 42m
- Frequency
- 6 times a week
- Estimated price
- €65–130
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €28–40
- Website
- https://www.italotreno.it/en
- Smart Economy
- €28–40
- Smart Flex
- €29–40
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once a week
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €11–19
- Website
- https://www.flixbus.co.uk
Bus from Madrid to Genoa
- Ave. Duration
- 21h
- Frequency
- Once daily
- Estimated price
- €90–160
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Florence Villa Constanza Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- €14–24
- Website
- https://www.flixbus.co.uk
Bus from Padua to Perugia
- Ave. Duration
- 8h 15m
- Frequency
- Twice daily
- Estimated price
- €27–50
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Barcelona - North Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 16h 25m
- Frequency
- Twice daily
- Estimated price
- €65–95
- Website
- https://www.blablacar.co.uk/bus
Bus from Genoa to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 4 times a day
- Estimated price
- €23–35
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Méndez Álvaro Estación Sur to Padova
- Ave. Duration
- 27h 34m
- Frequency
- Once a week
- Estimated price
- €60–75
- Schedules at
- tabitatour.ro
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