Travel from Spain to Italy is: Partially open. See details.
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There are 9 ways to get from Madrid Airport (MAD) to Rome by plane, train, night bus, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Rome  •  2h 57m

  1. Fly from Madrid (MAD) to Rome (FCO) MAD - FCO

8 alternative options

Fly to Rome Ciampino  •  4h 39m

  1. Fly from Madrid (MAD) to Rome Ciampino (CIA) MAD - CIA

Fly to Florence, train  •  4h 28m

  1. Fly from Madrid (MAD) to Florence (FLR) MAD - FLR
  2. Take the train from Firenze S.M.N. to Roma Termini

Fly to Naples, train  •  4h 38m

  1. Fly from Madrid (MAD) to Naples (NAP) MAD - NAP
  2. Take the train from Napoli Centrale to Roma Termini

Train, night bus  •  21h 35m

  1. Take the train from Madrid-Puerta De Atocha to Marseille St Charles Ave
  2. Take the night bus from Marseille to Florence
  3. Take the train from Firenze S.M.N. to Roma Termini Fr / ...

Bus, train  •  24h 56m

  1. Take the bus from Madrid Barajas Airport to Poitiers Futuroscope 793
  2. Take the train from Poitiers to Chambéry - Challes-les-Eaux Tgv
  3. Take the train from Chambery Challes Les Eaux to Milano Centrale Fr
  4. Take the train from Milano Centrale Station to Roma Termini

Bus via Genoa  •  31h 10m

  1. Take the bus from Madrid Mendez Alvaro Estacion Sur to Genoa Train station Lisbon Oriente - Sofia Central Bus Station
  2. Take the bus from Genoa to Rome Tiburtina Bus station 510 / ...

Bus  •  2 days 7h

  1. Take the bus from Madrid to Roma

Drive  •  18h 34m

  1. Drive from Madrid Airport (MAD) to Rome 1941.9 km

Madrid Airport (MAD) to Rome by subway, train, night bus and tram

5 Weekly Services
21h 35m Average Duration
€138 Cheapest Price
See schedules
Spain → Italy
Partially open

Travel safe during COVID-19

International entry into Italy from Spain

  • Entry is partially open for citizens and permanent residents of Spain
Show more details
Allowed for: Citizens and permanent residents of EU Schengen Area (EU countries, Iceland, Liechtenstein, Norway, and Switzerland), Andorra, Argentina, Australia, Bahrain, Canada, Chile, Colombia, Gibraltar, Hong Kong, Indonesia, Isle of Man, Israel, Japan, Kuwait, Macau, Monaco, New Zealand, Peru, Qatar, Rwanda, San Marino, Saudi Arabia, South Korea, Taiwan, United Arab Emirates, United Kingdom, United States, Uruguay and Vatican

Restricted for: Botswana, Eswatini, Lesotho, Malawi, Mozambique, Namibia, South Africa and Zimbabwe

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Conditions of entry into Italy from Spain

  • Travellers must present a negative COVID-19 test as either a RT-PCR performed within 48 hours prior to arrival, or an Antigen test performed within 24 hours prior to arrival
  • 5-day mandatory self-quarantine and COVID-19 test at the end of the isolation period
  • Travellers with a certificate of vaccination are exempt from compulsory quarantine
  • Travellers who have recovered from COVID-19 in the last 6 months are exempt from compulsory quarantine (certificate needed)
  • Passenger Locator Form (PLF) required
This applies to arrivals from Spain
Show more details
  • Travellers must present a negative COVID-19 test as either a RT-PCR performed within 48 hours prior to arrival, or an Antigen test performed within 24 hours prior to arrival
This applies to arrivals from EU Schengen Area (EU countries, Iceland, Liechtenstein, Norway, and Switzerland), Andorra, Faroe Islands, Gibraltar, Greenland, Guadeloupe, Guernsey, Guyana, Isle of Man, Jersey, Martinique, Monaco, Réunion, Svalbard and Jan Mayen and United Kingdom
  • 10-day mandatory self-quarantine and COVID-19 test at the end of the isolation period
This doesn't apply to arrivals from: EU Schengen Area (EU countries, Iceland, Liechtenstein, Norway, and Switzerland), Andorra, Argentina, Australia, Bahrain, Canada, Chile, Colombia, Gibraltar, Guadeloupe, Guernsey, Guyana, Hong Kong, Indonesia, Isle of Man, Israel, Japan, Jersey, Kuwait, Macau, Martinique, Mayotte, Monaco, New Zealand, Peru, Qatar, Réunion, Rwanda, San Marino, Saudi Arabia, South Korea, Svalbard and Jan Mayen, Taiwan, United Arab Emirates, United Kingdom, United States, Uruguay and Vatican
  • COVID-19 testing required within 72 hours from entering the country
This doesn't apply to arrivals from: EU Schengen Area (EU countries, Iceland, Liechtenstein, Norway, and Switzerland), Andorra, Gibraltar, Guernsey, Isle of Man, Monaco and United Kingdom unless other countries have been visited within the past 14 days prior to arrival
  • 5-day mandatory self-quarantine and COVID-19 test at the end of the isolation period
  • Travellers with a certificate of vaccination are exempt from compulsory quarantine
  • Travellers who have recovered from COVID-19 in the last 6 months are exempt from compulsory quarantine (certificate needed)
This applies to arrivals from EU Schengen Area (EU countries, Iceland, Liechtenstein, Norway, and Switzerland), Andorra, Argentina, Australia, Bahrain, Canada, Chile, Colombia, Gibraltar, Guernsey, Hong Kong, Indonesia, Isle of Man, Israel, Japan, Jersey, Kuwait, Macau, Monaco, New Zealand, Peru, Qatar, Rwanda, Saudi Arabia, South Korea, Taiwan, United Arab Emirates, United Kingdom, United States and Uruguay
  • Passenger Locator Form (PLF) required
This doesn't apply to arrivals from: San Marino and Vatican

Show less

Rules to follow in Italy

1.5m

Mandatory

Mandatory

Considerations leaving from Spain

The official advice is to avoid non-essential international travel to high risk countries

Frequently Asked Questions


Yes, but conditions apply when entering Italy from Spain.

Explore options for future travel

Domestic travel is not restricted, but some conditions may apply

  • Face masks are mandatory
  • There is a social distancing requirement of 1.5 metres
  • Observe COVID-19 safety rules
  • Nationwide control measures in place
  • Inter-regional travel is permitted
  • Health pass is required for long-distance travel by plane, train or coach, as well as in some public venues
  • Regional restriction measures in place

Explore travel options

The national COVID-19 helpline number in Rome is 1500.

Wearing a face mask on public transport in Rome is mandatory.

The social distance requirement in Rome is 1.5 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 1500.

No, but conditions apply when returning to Spain from Italy.

See options for return travel.

Last updated: 15 Jan 2022
Exceptions may apply, for full details: European Union.

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Madrid Airport (MAD) to Rome is to fly which costs €27 - €170 and takes 4h 39m.

More details

The fastest way to get from Madrid Airport (MAD) to Rome is to fly. Taking this option will cost €26 - €210 and takes 2h 57m.

More details

No, there is no direct bus from Madrid Airport (MAD) to Rome station. However, there are services departing from Aeropuerto T4 and arriving at Rome Tiburtina Bus station via Estación De Atocha, Madrid Mendez Alvaro Estacion Sur and Genoa. The journey, including transfers, takes approximately 31h 10m.

More details

The distance between Madrid Airport (MAD) and Rome is 1354 km. The road distance is 1941.9 km.

Get driving directions

The best way to get from Madrid Airport (MAD) to Rome without a car is to train and night bus which takes 21h 35m and costs €130 - €240.

More details

It takes approximately 2h 57m to get from Madrid Airport (MAD) to Rome, including transfers.

More details

Madrid Airport (MAD) to Rome bus services, operated by ALSA, depart from Madrid station.

More details

The best way to get from Madrid Airport (MAD) to Rome is to fly which takes 2h 57m and costs €26 - €210. Alternatively, you can bus via Genoa, which costs €70 - €100 and takes 31h 10m.

Mode details

The quickest flight from Madrid Airport to Rome Airport is the direct flight which takes 2h 15m.

Search flights

Madrid Airport (MAD) to Rome bus services, operated by ALSA, arrive at Roma station.

More details

Map of how to get from Madrid Airport (MAD) to Rome.
Launch map view
  • Distance: 1353.7 km
  • Duration: 2h 57m

What companies run services between Madrid Airport (MAD), Spain and Rome, Italy?

Wizz Air, Alitalia and six other airlines fly from Madrid Airport (MAD) to Rome every 2 hours. Alternatively, you can take a bus from Madrid Airport (MAD) to Rome via Estación De Atocha, Estación Sur, Madrid Mendez Alvaro Estacion Sur, Genoa Train station, and Genoa in around 31h 10m.

Airlines
Ryanair
Website
ryanair.com
Flights from Madrid to Rome
Ave. Duration
2h 32m
When
Every day
Estimated price
€19 - €260
Flights from Madrid to Rome via Palermo
Ave. Duration
5h 25m
When
Saturday
Estimated price
€19 - €260
Flights from Madrid to Rome Ciampino via Cologne Bonn
Ave. Duration
5h 30m
When
Saturday
Estimated price
€24 - €170
Flights from Madrid to Rome Ciampino via Palma Mallorca
Ave. Duration
4h 52m
When
Monday and Friday
Estimated price
€24 - €170
Flights from Madrid to Rome Ciampino via London Stansted
Ave. Duration
6h 25m
When
Tuesday and Thursday
Estimated price
€24 - €170
Flights from Madrid to Rome Ciampino via Lisbon
Ave. Duration
8h 20m
When
Wednesday
Estimated price
€24 - €170
Flights from Madrid to Rome Ciampino via Turin, Cagliari
Ave. Duration
8h 30m
When
Monday
Estimated price
€24 - €170
Flights from Madrid to Rome Ciampino via Valencia
Ave. Duration
3h 45m
When
Saturday
Estimated price
€24 - €170
Flights from Madrid to Rome Ciampino via Sevilla
Ave. Duration
4h 30m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
€24 - €170
Flights from Madrid to Naples
Ave. Duration
2h 30m
When
Monday, Wednesday, Friday and Sunday
Estimated price
€24 - €160
Flights from Madrid to Naples via Palma Mallorca
Ave. Duration
5h 10m
When
Thursday
Estimated price
€24 - €160
Flights from Madrid to Naples via Milan Bergamo
Ave. Duration
5h 20m
When
Saturday
Estimated price
€24 - €160
Flights from Madrid to Naples via Milan Malpensa
Ave. Duration
5h 25m
When
Wednesday
Estimated price
€24 - €160
Iberia
Website
iberia.com
Flights from Madrid to Rome
Ave. Duration
2h 30m
When
Every day
Estimated price
€40 - €410
Flights from Madrid to Rome via Barcelona
Ave. Duration
4h 10m
When
Monday, Tuesday and Wednesday
Estimated price
€85 - €460
Flights from Madrid to Florence
Ave. Duration
2h 21m
When
Every day
Estimated price
€65 - €650
Flights from Madrid to Florence via Barcelona
Ave. Duration
4h 35m
When
Friday and Sunday
Estimated price
€90 - €650
Flights from Madrid to Florence via Paris Orly
Ave. Duration
4h 55m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
€55 - €650
Flights from Madrid to Naples
Ave. Duration
2h 37m
When
Every day
Estimated price
€45 - €330
Flights from Madrid to Naples via Barcelona
Ave. Duration
5h 20m
When
Monday, Tuesday, Thursday, Friday and Sunday
Estimated price
€90 - €350
Vueling Airlines
Website
vueling.com
Flights from Madrid to Rome
Ave. Duration
2h 30m
When
Every day
Estimated price
€40 - €410
Flights from Madrid to Rome via Barcelona
Ave. Duration
4h 10m
When
Monday, Tuesday and Wednesday
Estimated price
€85 - €460
Flights from Madrid to Florence
Ave. Duration
2h 21m
When
Every day
Estimated price
€65 - €650
Flights from Madrid to Florence via Barcelona
Ave. Duration
4h 35m
When
Friday and Sunday
Estimated price
€90 - €650
Flights from Madrid to Florence via Paris Orly
Ave. Duration
4h 55m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
€55 - €650
Flights from Madrid to Naples via Barcelona
Ave. Duration
5h 20m
When
Monday, Tuesday, Thursday, Friday and Sunday
Estimated price
€90 - €350
Alitalia
Website
alitalia.com
Flights from Madrid to Rome
Ave. Duration
2h 28m
When
Every day
Estimated price
€35 - €460
Air Europa
Website
aireuropa.com
Flights from Madrid to Rome
Ave. Duration
2h 28m
When
Every day
Estimated price
€35 - €460
Lufthansa
Website
lufthansa.com
Flights from Madrid to Rome via Munich
Ave. Duration
5h 15m
When
Every day
Estimated price
€100 - €600
Flights from Madrid to Florence via Munich
Ave. Duration
5h 25m
When
Every day
Estimated price
€110 - €750
Flights from Madrid to Naples via Munich
Ave. Duration
5h 30m
When
Monday, Wednesday, Friday, Saturday and Sunday
Estimated price
€110 - €400
Wizz Air
Website
wizzair.com
Flights from Madrid to Rome
Ave. Duration
2h 15m
When
Monday, Wednesday and Friday
Estimated price
€17 - €95
Air France
Website
airfrance.com
Flights from Madrid to Rome via Paris CDG
Ave. Duration
5h 10m
When
Monday, Thursday, Friday and Sunday
Estimated price
€90 - €800
Train operators
Trenitalia Frecce

Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze S.M.N. to Roma Termini
Ave. Duration
1h 35m
Frequency
Every 30 minutes
Estimated price
€21 - €75
Website
Trenitalia Frecce
Super Economy
€21 - €29
Base Standard
€40 - €55
Base Premium
€50 - €75
Train from Napoli Centrale to Roma Termini
Ave. Duration
1h 16m
Frequency
Every 30 minutes
Estimated price
€18 - €65
Website
Trenitalia Frecce
Super Economy
€18 - €25
Base Standard
€35 - €50
Base Premium
€45 - €65
ItaloTreno

Private train company Italotreno operates high-speed trains in Italy on the same tracks as Trenitalia. The routes service 21 stations across the country, including popular routes Milan-Florence, Rome-Venice and Bologna-Naples. Choose from four classes of service, all with free Wi-Fi: Smart, Comfort, Prima and Club Executive. Italo also operates Italobus – an integrated train-bus service that takes passengers from the main train stations to other Italian cities.

Contact Details
Phone
+39 060708
Website
italotreno.it
Train from Firenze Santa Maria Novella to Roma Termini
Ave. Duration
1h 36m
Frequency
Twice daily
Estimated price
€19 - €55
Website
Italo Treno
Smart Economy
€21 - €30
Smart Low Cost
€19 - €27
Smart Flex
€40 - €55
Train from Napoli Centrale Station to Roma Termini
Ave. Duration
1h 16m
Frequency
5 times a day
Estimated price
€17 - €50
Website
Italo Treno
Smart Economy
€19 - €27
Smart Low Cost
€17 - €24
Smart Flex
€35 - €50
Train from Milano Centrale Station to Roma Termini
Ave. Duration
2h 39m
Frequency
Hourly
Estimated price
€30 - €90
Website
Italo Treno
Smart Economy
€30 - €50
Smart Low Cost
€30 - €45
Smart Flex
€65 - €90
Trenitalia Intercity

Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze S.M.N. to Roma Termini
Ave. Duration
2h 35m
Frequency
6 times a week
Estimated price
€16 - €24
Website
Trenitalia Intercity
2nd Class
€16 - €24
Train from Napoli Centrale to Roma Termini
Ave. Duration
2h 3m
Frequency
Every 3 hours
Estimated price
€14 - €20
Website
Trenitalia Intercity
2nd Class
€14 - €20
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Napoli Centrale to Roma Termini
Ave. Duration
2h 55m
Frequency
Every 4 hours
Estimated price
€14 - €29
Website
Trenitalia
1st Class
€26 - €29
Train from Chambery Challes Les Eaux to Milano Centrale
Ave. Duration
3h 22m
Frequency
Twice daily
Estimated price
€22 - €45
Website
Trenitalia
1st Class
€41 - €45
Frequently asked questions
Is there Wi-Fi on Trenitalia?
Yes - Wi-Fi is available on both Frecciarossa and Frecciargento services, and may be accessed free of charge. Services require either a mobile phone number or credit card for verification purposes and allow access for 24 hours.
Are there power outlets on Trenitalia?
Yes - Frecce services include a power socket for each seat.
Does Trenitalia offer meals or snacks?
Yes - Frecciarossa and Frecciargento services often offer bar and restaurant options, though this depends on the individual route and train type. Business, Premium and First Class tickets include a complimentary drink and snack. Some services may offer restaurant, FRECCIABistro or pre-booked, in-seat meal options. Please check your service as options vary.
For more information, please visit this page
Renfe SNCF
Phone
+34 902 320 320
Email
comunicacion@renfe.es
Website
renfe-sncf.com
Train from Madrid-Puerta De Atocha to Marseille St Charles
Ave. Duration
7h 45m
Frequency
Once daily
Estimated price
€85 - €130
Website
renfe-sncf.com
SNCF

France’s state-owned railway company is a fast and efficient way of travelling around the country, with over 14,000 trains operating daily. SNCF runs the country’s extensive rail network, including the high-speed TGV network, regional TER trains and local Intercités. It also operates international routes including Eurostar and Thalys, as well as the low-cost, long-distance Ouigo services that run on limited routes across France. Book up to 3 months in advance for the cheapest fares. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Poitiers to Chambéry - Challes-les-Eaux
Ave. Duration
4h 33m
Frequency
4 times a week
Estimated price
€95 - €180
Website
Oui.SNCF
2nd Class
€95 - €140
Rail 1st Class
€120 - €180
TGV inOui

France’s high-speed TGV train network runs at speeds of up to 320km/h connecting major cities across France and into neighbouring countries. All TGV tickets include a seat reservation; seating is 1+2 in 1st class, 2+2 in 2nd class. Popular routes include Paris to Marseille and Paris to Strasbourg. Most TGVs have a cafe area, power points at each seat and WiFi.

Contact Details
Phone
0033 892 353535
Website
en.oui.sncf
Train from Poitiers to Chambéry-Challes-les-Eaux
Ave. Duration
4h 33m
Frequency
Twice a week
Estimated price
€120 - €170
Website
Oui.SNCF
2nd Class
€120 - €140
1st Class
€140 - €170
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 30 300 137 300
Email
service@flixbus.com
Website
flixbus.de
Night bus from Marseille to Florence
Ave. Duration
9h 15m
Frequency
5 times a week
Estimated price
€30 - €40
Website
flixbus.co.uk
Bus from Madrid Barajas Airport to Poitiers Futuroscope
Ave. Duration
11h 25m
Frequency
5 times a week
Estimated price
€40 - €55
Website
flixbus.co.uk
Bus from Genoa to Rome Tiburtina Bus station
Ave. Duration
6h
Frequency
3 times a day
Estimated price
€25 - €30
Website
flixbus.co.uk
Frequently asked questions
Is there Wi-Fi on FlixBus?
Yes - FlixBus offers free Wi-Fi
Are there power outlets on FlixBus?
Yes
Does FlixBus offer meals or snacks?
Yes - snacks and drinks may be purchased from the driver. Please note, this is not available on all services.
For more information, please visit this page
Union Ivkoni
Phone
02/989 0000
Website
union-ivkoni.com
Bus from Madrid Mendez Alvaro Estacion Sur to Genoa Train station
Ave. Duration
22h
Frequency
3 times a week
Estimated price
€45 - €65
Website
Union Ivkoni
ALSA

A Spanish subsidiary of National Express, ALSA provides bus and coach services across Spain and neighbouring countries including Portugal, France, Germany, the Netherlands, Italy, Poland and Malta. Founded in 1923, ALSA values service and the customer experience. Buses are equipped with communal TV screens showing movies, individual behind-seat screens, ALSA radio, app for books and music, and free WiFi. ALSA services are accessible to people with disabilities, and guide dogs are welcome on all journeys. There are three types of tickets on offer (Frequent Traveller Pass, Share Pass and ALSA Pass), along with discounts for senior citizens, students and children.

Contact Details
Phone
+34 902 42 22 42
Email
alsa@alsa.es
Website
alsa.es
Bus from Madrid to Roma
Ave. Duration
2 days 5h
Frequency
Once daily
Estimated price
€210 - €300
Website
alsa.com

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Madrid Airport (MAD) to Rome is 1942 km. It takes approximately 18h 34m to drive from Madrid Airport (MAD) to Rome.

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Wizz Air, Alitalia, Air Europa and five other airlines offer flights from Madrid Airport to Rome Airport.

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Book your Madrid Airport (MAD) to Rome bus tickets online with Omio and Busbud.

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