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How to get fromMadison to St. Louis (Region)by plane, bus, train, bus (Flixbus), or car

Find Transport to St. Louis (Region)

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There are 7 ways to get from Madison to St. Louis (Region) by plane, bus, train, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Dane County Regional Airport-Truax Field

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Lambert–St. Louis International Airport (STL)plane plane MSN - STL
    5h 35m
    $115–805

  2. Bus

    cheapest
    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    11h 2m
    $66–126

  3. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    9h 46m
    $106–236

  4. Drive 358.6 mi

    1. Drive from Madison to St. Louis (Region)car car 358.6 mi
    5h 54m
    $66–95

  5. Bus to General Mitchell International Airport, fly

    1. Take the bus from UW-Madison to Milwaukee, WI - Amtrakbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    5h 17m
    $135–892

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    5h 59m
    $297–603

  7. Bus, train via Milwaukee

    1. Take the bus from UW-Madison to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    9h 55m
    $114–260

Madison to St. Louis (Region) by bus and train

Calendar38Weekly Services
Duration9h 46mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

What companies run services between Madison, WI, USA and St. Louis (Region), MO, USA?

American Airlines, United Airlines, and Delta fly from Dane County Regional Airport-Truax Field (MSN) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from 250 N. Lake St - Madison UW Campus to St Louis Bus Station via W Jackson Blvd, after S Clinton St and Chicago Bus Station in around 11h 2m.

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