There are 10 ways to get from Madison to Louisville by plane, bus (Flixbus, Amtrak), bus, train, car, or bus (Greyhound, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Dane County Regional Airport-Truax Field to Louisville International Airport
best- Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane MSN - SDF
6h 21m$98–655Bus
cheapest- Take the bus from Madison to Indianapolisbus FlixBus 2514
- Take the bus from Indianapolis Union Station to Louisville, KYbus Chicago
10h 54m$67–140Bus, train via Milwaukee
- Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
13h 23m$81–194Drive 440 mi
- Drive from Madison to Louisvillecar 440 mi
7h 32m$81–116Fly Dane County Regional Airport-Truax Field to Blue Grass Airport, drive
- Fly from Dane County Regional Airport-Truax Field (MSN) to Blue Grass Airport (LEX)plane MSN - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
6h 28m$85–461Bus to Chicago O'Hare International Airport, fly to Louisville International Airport
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane ORD - SDF
6h 40m$211–593Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane ORD - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
6h 44m$73–339Bus to Chicago Midway International Airport, fly to Louisville International Airport
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane MDW - SDF
7h 55m$100–603Bus via Chicago
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
11h 37m$79–146Bus, train
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
13h 19m$74–141
Madison to Louisville by bus and foot
Questions & Answers
The cheapest way to get from Madison to Louisville is to bus which costs $65 - $140 and takes 10h 54m.
The fastest way to get from Madison to Louisville is to fly which takes 6h 21m and costs $95 - $700.
No, there is no direct bus from Madison to Louisville. However, there are services departing from Madison and arriving at Louisville, KY via Indianapolis Union Station. The journey, including transfers, takes approximately 10h 54m.
The distance between Madison and Louisville is 406 miles. The road distance is 442.6 miles.
The best way to get from Madison to Louisville without a car is to bus which takes 10h 54m and costs $65 - $140.
It takes approximately 6h 21m to get from Madison to Louisville, including transfers.
Madison to Louisville bus services, operated by Flixbus USA, depart from Madison station.
The best way to get from Madison to Louisville is to fly which takes 6h 21m and costs $95 - $700. Alternatively, you can bus, which costs $65 - $140 and takes 10h 54m.
Madison to Louisville bus services, operated by Flixbus USA, arrive at Indianapolis station.
Louisville is 1h ahead of Madison. It is currently 3:49 AM in Madison and 4:49 AM in Louisville.
What companies run services between Madison, WI, USA and Louisville, KY, USA?
Delta, United Airlines, and American Airlines fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF) every 2 hours. Alternatively, you can take a bus from Madison to Louisville, KY via Indianapolis and Indianapolis Union Station in around 10h 54m.
- Website
- aa.com
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–650
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $160–850
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $210–1,000
Flights from Dane County Regional Airport-Truax Field to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–440
Flights from Dane County Regional Airport-Truax Field to Blue Grass Airport via Charlotte
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $110–600
Flights from Dane County Regional Airport-Truax Field to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $150–750
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $55–390
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–280
- Website
- united.com
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $95–650
Flights from Dane County Regional Airport-Truax Field to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $70–440
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $55–390
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $40–280
- Website
- delta.com
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Detroit
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $120–700
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Minneapolis
- Ave. Duration
- 5h 30m
- When
- Saturday and Sunday
- Estimated price
- $140–800
Flights from Dane County Regional Airport-Truax Field to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $160–850
Flights from Dane County Regional Airport-Truax Field to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–480
Flights from Dane County Regional Airport-Truax Field to Blue Grass Airport via Atlanta
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $110–600
Flights from Dane County Regional Airport-Truax Field to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 7h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
- Website
- southwest.com
Flights from Chicago Midway International Airport to Louisville International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $75–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Madison to Indianapolis
- Ave. Duration
- 7h 15m
- Frequency
- 6 times a week
- Estimated price
- $45–95
- Schedules at
- flixbus.com
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $21–29
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- badgerbus.com
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $23–30
- Website
- https://badgerbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $7–55
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 800-236-1240
- Website
- golamers.com
Bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrak
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $21–50
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
- Phone
- +1 608-752-5407
- vangalder@coachusa.com
- Website
- coachusa.com
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $20–40
- Website
- https://www.coachusa.com/van-galder-bus-company
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $22–45
- Website
- https://www.coachusa.com/van-galder-bus-company
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Indianapolis Union Station
- Ave. Duration
- 3h 5m
- Frequency
- 5 times a day
- Estimated price
- $35–60
- Website
- https://www.greyhound.com/
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More Questions & Answers
Yes, the driving distance between Madison to Louisville is 443 miles. It takes approximately 7h 32m to drive from Madison to Louisville.
Book your Madison to Louisville bus tickets online with Omio.
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