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How to get fromMachala to Santa Isabelby taxi, plane, car, or bus

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There are 8 ways to get from Machala to Santa Isabel by taxi, plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to José Joaquín De Olmedo International Airport, fly to São Paulo–Guarulhos International Airport

    best
    1. Take the taxi from Machala to Guayaquil-Airport-GYEtaxi taxi
    2. Fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU)plane plane GYE - GRU
    12h 48m
    R$2,336–3,527

  2. Bus

    cheapest
    1. Take the bus from Machala to Huaquillasbus bus
    2. Take the bus from Tumbes to Lima Terminal Exclucivabus bus
    3. Take the bus from Lima Javier Prado to Icabus bus
    4. Take the bus from Ica to Tietê Bus Terminalbus bus
    5. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    5d 9h
    R$1,641–3,867

  3. Drive, bus

    1. Drive from Machala to Tumbescar car
    2. Take the bus from Tumbes to Lima Terminal Exclucivabus bus
    3. Take the bus from Lima Javier Prado to Icabus bus
    4. Take the bus from Ica to Porto Velhobus bus
    5. Take the bus from Rodoviária de Porto Velho to Terminal Rodoviário de Santo Andrébus bus
    4d 19h
    R$3,548–4,683

  4. Drive  5,649.3 km

    1. Drive from Machala to Santa Isabelcar car 5,649.3 km
    3d 4h
    R$3,493–5,046

  5. Bus to Tumbes, fly to São Paulo–Guarulhos International Airport

    1. Take the bus from Machala to Huaquillasbus bus
    2. Fly from Tumbes (TBP) to São Paulo–Guarulhos International Airport (GRU)plane plane TBP - GRU
    12h 49m
    R$1,775–4,926

  6. Bus to Tumbes, fly to São Paulo–Congonhas Airport, bus

    1. Take the bus from Machala to Huaquillasbus bus
    2. Fly from Tumbes (TBP) to São Paulo–Congonhas Airport (CGH)plane plane TBP - CGH
    3. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    15h 43m
    R$1,652–4,823

  7. Bus to Piura International Airport, fly to São Paulo–Guarulhos International Airport

    1. Take the bus from Machala to Piurabus bus
    2. Fly from Piura International Airport (PIU) to São Paulo–Guarulhos International Airport (GRU)plane plane PIU - GRU
    17h 14m
    R$2,025–5,232

  8. Bus via Máncora

    1. Take the bus from Machala to Máncorabus bus
    2. Take the bus from Máncora to Lima 28 de Juliobus bus
    3. Take the bus from Lima to Icabus bus
    4. Take the bus from Ica to Tietê Bus Terminalbus bus
    5. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    5d 13h
    R$1,673–3,933

José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU) flights

Calendar53Weekly Planes
Duration10h 47mAverage Duration
TicketR$1,213Cheapest Price
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Comparing Your Travel Options

Map of how to get from Machala to Santa Isabel.ExpandLaunch map view
  • Distance: 4,536.5 km
  • Duration: 12h 48m

What companies run services between Machala, Ecuador and Santa Isabel, Brazil?

You can take a bus from Machala to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasil via Huaquillas, Tumbes, Lima Terminal Excluciva, Lima Javier Prado, Ica, Tietê Bus Terminal, and Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil in around 5d 9h.

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