China Railways G-Class operates a train from Macau to Guangzhou hourly. Tickets cost $11 - $40 and the journey takes 27 min. Guang Zhou Metro also services this route every 5 minutes. Alternatively, China Bus Guide operates a bus from Macau to Guangzhou every 30 minutes. Tickets cost $8 - $12 and the journey takes 1 h 50 min.
How to get from Macau to Guangzhou
From Zhuhai train to Guangzhou South then line 2 Guangzhou Metro to Haizhu Square. 1 h $31. From Zhuhai Gongbei Tongda bus to Guangzhou Provincial. 1 h 50 min $10. From Zhuhai Gongbei bus to Jiuzhougang then bus to Guangzhou. 3 h 1 min $14. From Macau taxi to Guangzhou. 1 h 29 min $172. From Macau drive to Guangzhou. 1 h 29 min.