There are 7 ways to get from Lyon to Siena by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
8h 57m€95–164Bus via Florence
cheapest- Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus Itabus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
14h 7m€49–78Bus
- Take the bus from Lyon to Sienabus 516 / ...
11h 20m€65–100Drive 728.1 km
- Drive from Lyon to Sienacar 728.1 km
8h 1m€118–170Fly from Lyon–Saint Exupéry Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane LYS - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 14m€74–274Train via Turin
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
9h 22m€98–176Train to Geneva International Airport, fly, train
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane GVA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
10h 3m€133–329
Lyon to Siena by train
Comparing Your Travel Options
The cheapest way to get from Lyon to Siena is to bus via Florence which costs €45 - €80 and takes 14h 7m.
The fastest way to get from Lyon to Siena is to fly and train which takes 6h 14m and costs €70 - €280.
Yes, there is a direct bus departing from Lyon and arriving at Siena. Services depart six times a week, and operate Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The journey takes approximately 11h 20m.
No, there is no direct train from Lyon to Siena. However, there are services departing from Lyon Part Dieu and arriving at Siena via Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 8h 57m.
The distance between Lyon and Siena is 842 km. The road distance is 728.1 km.
The best way to get from Lyon to Siena without a car is to train which takes 8h 57m and costs €90 - €170.
It takes approximately 8h 57m to get from Lyon to Siena, including transfers.
Lyon to Siena bus services, operated by FlixBus, depart from Lyon station.
Lyon to Siena train services, operated by Trenitalia, depart from Lyon Part Dieu station.
The best way to get from Lyon to Siena is to train which takes 8h 57m and costs €90 - €170. Alternatively, you can bus, which costs €65 - €100 and takes 11h 20m.
What companies run services between Lyon, France and Siena, Italy?
You can take a train from Lyon Part Dieu to Siena via Milano Centrale and Firenze S.M.N. in around 8h 57m. Alternatively, FlixBus operates a bus from Lyon to Siena 6 times a week. Tickets cost €65–100 and the journey takes 11h 20m.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 33m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €70–390
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €180–650
Flights from Geneva International Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- €110–700
- Website
- swiss.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- €85–180
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- €100–260
- Website
- ita-airways.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €85–180
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- €100–260
- Website
- volotea.com
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport
- Ave. Duration
- 1h 20m
- When
- Friday and Sunday
- Estimated price
- €26–200
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- €100–260
- Website
- airdolomiti.it
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Tuesday and Sunday
- Estimated price
- €180–650
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- 4 times a day
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- €60–110
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 58m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h 23m
- Frequency
- Once daily
- Estimated price
- €50–85
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €28–50
- Website
- Oui.SNCF
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- €30–50
- Website
- TGV inOui
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Lyon to Siena
- Ave. Duration
- 11h 20m
- Frequency
- 6 times a week
- Estimated price
- €65–100
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 12h 5m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- Itabus S.p.A.
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Lyon to Siena bus services, operated by FlixBus, arrive at Siena station.
Lyon to Siena train services, operated by Trenitalia, arrive at Milano Centrale station.
Yes, the driving distance between Lyon to Siena is 728 km. It takes approximately 8h 1m to drive from Lyon to Siena.
Book your Lyon to Siena train tickets online with Omio.
Book your Lyon to Siena bus tickets online with Omio and FlixBus.
There are 2388+ hotels available in Siena.




































