There are 8 ways to get from Lyon to Siena by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
9h 30mBus via Turin
cheapest- Take the bus from Lyon Lyon Perrache Bus Station to Turin Stura Bus Stationbus Itabus
- Take the bus from Turin Stura Bus Station to Siena Central Train Stationbus Itabus
14h 44m€32–99Bus
- Take the bus from Lyon to Sienabus 516
11h 20m€60–110Drive 728.4 km
- Drive from Lyon to Sienacar 728.4 km
8h 1m€114–165Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane LYS - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 39m€88–218Train
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
9h 37m€93–233Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane LYS - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
7h 41m€102–280Train to Geneva International Airport, fly to Florence Peretola Airport, train
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane GVA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
10h 19m€112–357
Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Lyon to Siena is to bus via Turin which costs €30 - €100 and takes 14h 44m.
The fastest way to get from Lyon to Siena is to fly and train which takes 6h 39m and costs €85 - €220.
Yes, there is a direct bus departing from Lyon and arriving at Siena. Services depart once a week, and operate Sunday. The journey takes approximately 11h 20m.
No, there is no direct train from Lyon to Siena. However, there are services departing from Lyon Part Dieu and arriving at Siena via Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 9h 37m.
The distance between Lyon and Siena is 818 km. The road distance is 728.4 km.
The best way to get from Lyon to Siena without a car is to train and bus which takes 9h 30m and costs .
It takes approximately 9h 30m to get from Lyon to Siena, including transfers.
Lyon to Siena bus services, operated by FlixBus, depart from Lyon station.
Lyon to Siena train services, operated by Trenitalia S.p.A., depart from Lyon Part Dieu station.
The best way to get from Lyon to Siena is to bus which takes 11h 20m and costs €60 - €110. Alternatively, you can train, which costs €90 - €240 and takes 9h 37m.
What companies run services between Lyon, France and Siena, Italy?
FlixBus operates a bus from Lyon to Siena once a week. Tickets cost €60–110 and the journey takes 11h 20m. Alternatively, you can take a train from Lyon Part Dieu to Siena via Milano Centrale and Firenze S.M.N. in around 9h 37m.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- €80–170
Flights from Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 45m
- When
- Monday to Saturday
- Estimated price
- €80–330
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- €130–420
Flights from Geneva International Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- €140–440
- Website
- swiss.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- €75–400
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- €70–190
- Website
- ita-airways.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 15m
- When
- Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €75–400
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- €70–190
- Website
- airdolomiti.it
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 25m
- When
- Sunday
- Estimated price
- €130–420
Flights from Geneva International Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 3h 55m
- When
- Friday and Sunday
- Estimated price
- €140–440
- Website
- volotea.com
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport
- Ave. Duration
- 1h 20m
- When
- Friday
- Estimated price
- €50–170
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Monday to Friday
- Estimated price
- €380–800
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- €45–130
- Schedules at
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €23–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.italotreno.it/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 57m
- Frequency
- Every 3 hours
- Estimated price
- €25–35
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- €40–120
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lyon to Siena
- Ave. Duration
- 11h 20m
- Frequency
- Once a week
- Estimated price
- €60–110
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Lyon Lyon Perrache Bus Station to Turin Stura Bus Station
- Ave. Duration
- 5h 14m
- Frequency
- Twice daily
- Estimated price
- €14–35
- Website
- https://www.itabus.it/en/home
Bus from Turin Stura Bus Station to Siena Central Train Station
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- €18–65
- Website
- https://www.itabus.it/en/home
Want to know more about travelling around Italy
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More Questions & Answers
Lyon to Siena bus services, operated by FlixBus, arrive at Siena station.
Lyon to Siena train services, operated by Trenitalia S.p.A., arrive at Milano Centrale station.
Yes, the driving distance between Lyon to Siena is 728 km. It takes approximately 8h 1m to drive from Lyon to Siena.
Book your Lyon to Siena train tickets online with Omio.
Book your Lyon to Siena bus tickets online with Omio and FlixBus.
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