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How to get fromLyon to Sienaby train, bus, car, plane or train (Trenitalia)

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There are 8 ways to get from Lyon to Siena by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Turin

    best
    1. Take the train from Lyon Part Dieu to Torino Porta Susatrain train Fr
    2. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    9h 38m
    €109–202

  2. Bus

    cheapest
    1. Take the bus from Lyon to Sienabus bus 516 / ...
    11h 20m
    €50–95

  3. Drive 728.4 km

    1. Drive from Lyon to Sienacar car 728.4 km
    8h 1m
    €113–163

  4. Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 39m
    €99–258

  5. Train (Trenitalia)

    1. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    9h 44m
    €100–202

  6. Train, bus

    1. Take the train from Lyon Part Dieu to Genevetrain train Ter
    2. Take the bus from Geneve, Gare Routiere to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    14h 40m
    €75–143

  7. Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LYS - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 33m
    €91–316

  8. Train to Geneva International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    10h 7m
    €115–309

Lyon to Siena by train and bus

Calendar14Weekly Services
Duration9h 38mAverage Duration
Ticket€109Cheapest Price
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Questions & Answers

What companies run services between Lyon, France and Siena, Italy?

FlixBus operates a bus from Lyon to Siena once daily. Tickets cost €50–95 and the journey takes 11h 20m. Alternatively, you can take a train from Lyon Part Dieu to Siena via Milano Centrale and Firenze S.M.N. in around 9h 44m.

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