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How to get fromLyon to Sienaby train (Trenitalia), bus, car, plane, train, or train (Trenitalia, TGV)

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There are 9 ways to get from Lyon to Siena by train (Trenitalia), bus, car, plane, train, or train (Trenitalia, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    8h 53m
    €97–199

  2. Bus via Florence

    cheapest
    1. Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus bus Itabus
    2. Take the bus from Stazione Leopolda to Siena-Via Tozzibus bus 131R / ...
    14h 5m
    €55–105

  3. Bus

    1. Take the bus from Lyon to Sienabus bus 516 / ...
    11h 20m
    €65–120

  4. Drive 728.1 km

    1. Drive from Lyon to Sienacar car 728.1 km
    8h 1m
    €113–163

  5. Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 14m
    €99–247

  6. Train via Turin

    1. Take the train from Lyon Part Dieu to Chambery Challes Les Eauxtrain train Ter
    2. Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain train Tgv
    3. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    10h 28m
    €103–249

  7. Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LYS - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 58m
    €101–262

  8. Train to Geneva International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 58m
    €132–331

  9. Fly Lyon–Saint Exupéry Airport to Venice Marco Polo Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Venice Marco Polo Airport (VCE)plane plane LYS - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 38m
    €93–297

Lyon to Siena by train

Calendar28Weekly Trains
Duration8h 53mAverage Duration
Ticket€97Cheapest Price
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Questions & Answers

Map of how to get from Lyon to Siena.ExpandLaunch map view
  • Distance: 841.9 km
  • Duration: 8h 53m

What companies run services between Lyon, France and Siena, Italy?

You can take a train from Lyon Part Dieu to Siena via Milano Centrale and Firenze S.M.N. in around 8h 53m. Alternatively, FlixBus operates a bus from Lyon to Siena once daily. Tickets cost €65–110 and the journey takes 11h 20m. BlaBlaCar Bus also services this route once daily.

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