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How to get fromLyon to Sienaby train, bus, car, or plane

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There are 10 ways to get from Lyon to Siena by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus 131
    8h 48m
    €89–185

  2. Bus via Florence

    cheapest
    1. Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus bus Itabus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    14h 9m
    €54–95

  3. Bus

    1. Take the bus from Lyon to Sienabus bus 516 / ...
    11h 20m
    €55–90

  4. Drive 728.1 km

    1. Drive from Lyon to Sienacar car 728.1 km
    8h 1m
    €116–168

  5. Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    2. Take the train from Firenze Rifredi to Sienatrain train
    6h 39m
    €108–267

  6. Train, bus via Turin

    1. Take the train from Lyon Part Dieu to Torino Porta Susatrain train Fr
    2. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    9h 29m
    €98–197

  7. Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LYS - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    6h 45m
    €89–272

  8. Train to Geneva International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    3. Take the train from Firenze Rifredi to Sienatrain train
    10h 24m
    €136–353

  9. Fly Lyon–Saint Exupéry Airport to Venice Marco Polo Airport, train, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Venice Marco Polo Airport (VCE)plane plane LYS - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    8h 43m
    €92–299

  10. Fly Lyon–Saint Exupéry Airport to Fiumicino International Airport, train, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Fiumicino International Airport (FCO)plane plane LYS - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    8h 20m
    €110–284

Lyon to Siena by train and bus

Calendar14Weekly Services
Duration8h 48mAverage Duration
Ticket€89Cheapest Price
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Questions & Answers

Map of how to get from Lyon to Siena.ExpandLaunch map view
  • Distance: 818.9 km
  • Duration: 8h 48m

What companies run services between Lyon, France and Siena, Italy?

FlixBus operates a bus from Lyon to Siena once daily. Tickets cost €55–90 and the journey takes 11h 20m.

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