There are 8 ways to get from Lyon to Siena by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
9h 34mBus
cheapest- Take the bus from Lyon to Sienabus 516 / ...
11h 20m€45–70Drive 728.4 km
- Drive from Lyon to Sienacar 728.4 km
8h 1m€112–162Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane LYS - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 39m€88–218Train (Trenitalia)
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
9h 36m€92–210Bus via Florence
- Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus Itabus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
14h 9mFly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane LYS - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
7h 40m€101–280Train to Geneva International Airport, fly to Florence Peretola Airport, train
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane GVA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
10h 19m€112–305
Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Lyon to Siena is to bus which costs €45 - €70 and takes 11h 20m.
The fastest way to get from Lyon to Siena is to fly and train which takes 6h 39m and costs €85 - €220.
Yes, there is a direct bus departing from Lyon and arriving at Siena. Services depart once daily, and operate Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The journey takes approximately 11h 20m.
No, there is no direct train from Lyon to Siena. However, there are services departing from Lyon Part Dieu and arriving at Siena via Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 9h 36m.
The distance between Lyon and Siena is 818 km. The road distance is 728.4 km.
The best way to get from Lyon to Siena without a car is to train and bus which takes 9h 34m and costs .
It takes approximately 9h 34m to get from Lyon to Siena, including transfers.
Lyon to Siena bus services, operated by FlixBus, depart from Lyon station.
Lyon to Siena train services, operated by Trenitalia, depart from Lyon Part Dieu station.
The best way to get from Lyon to Siena is to bus which takes 11h 20m and costs €45 - €70. Alternatively, you can train, which costs €90 - €210 and takes 9h 36m.
What companies run services between Lyon, France and Siena, Italy?
FlixBus operates a bus from Lyon to Siena once daily. Tickets cost €45–70 and the journey takes 11h 20m. Alternatively, you can take a train from Lyon Part Dieu to Siena via Milano Centrale and Firenze S.M.N. in around 9h 36m.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- €65–370
Flights from Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- €80–320
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- €130–400
- Website
- swiss.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- €75–350
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- €70–200
- Website
- ita-airways.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 15m
- When
- Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €75–350
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- €70–200
- Website
- volotea.com
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport
- Ave. Duration
- 1h 20m
- When
- Friday
- Estimated price
- €45–170
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €400–900
- Website
- airdolomiti.it
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 25m
- When
- Sunday
- Estimated price
- €130–400
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €55–120
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- €40–110
- Schedules at
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €22–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 57m
- Frequency
- Every 3 hours
- Estimated price
- €25–35
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- €30–70
- Website
- https://www.sncf-connect.com/en-en
- 2nd Class
- €30–45
- 1st Class
- €55–70
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lyon to Siena
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- €45–70
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 12h 5m
- Frequency
- Twice daily
- Estimated price
- €29–85
- Website
- https://www.itabus.it/en/home
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 11h
- Frequency
- 6 times a week
- Estimated price
- €40–60
- Website
- https://www.blablacar.co.uk/bus
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More Questions & Answers
Lyon to Siena bus services, operated by FlixBus, arrive at Siena station.
Lyon to Siena train services, operated by Trenitalia, arrive at Milano Centrale station.
Yes, the driving distance between Lyon to Siena is 728 km. It takes approximately 8h 1m to drive from Lyon to Siena.
Book your Lyon to Siena train tickets online with Omio.
Book your Lyon to Siena bus tickets online with Omio and FlixBus.
There are 2277+ hotels available in Siena.








































