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How to get fromLyon to Sienaby train, bus, car, or plane

Find Transport to Siena

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There are 8 ways to get from Lyon to Siena by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus 131
    8h 49m
    €90–186

  2. Bus

    cheapest
    1. Take the bus from Lyon to Sienabus bus 516 / ...
    11h 20m
    €50–90

  3. Drive 728.4 km

    1. Drive from Lyon to Sienacar car 728.4 km
    8h 1m
    €114–164

  4. Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    2. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    5h 55m
    €97–254

  5. Train, bus via Turin

    1. Take the train from Lyon Part Dieu to Torino Porta Susatrain train Fr
    2. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    9h 31m
    €98–198

  6. Bus via Florence

    1. Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus bus Itabus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    14h 8m

  7. Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train, bus

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LYS - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    6h 45m
    €89–282

  8. Train to Geneva International Airport, fly to Florence Peretola Airport, bus

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    3. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    9h 40m
    €125–331

Lyon to Siena by train and bus

Calendar14Weekly Services
Duration8h 49mAverage Duration
Ticket€90Cheapest Price
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Questions & Answers

What companies run services between Lyon, France and Siena, Italy?

FlixBus operates a bus from Lyon to Siena once daily. Tickets cost €50–90 and the journey takes 11h 20m.

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