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How to get fromLyon to Sienaby train, bus, car, plane or train (Trenitalia)

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There are 8 ways to get from Lyon to Siena by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Lyon Part Dieu to Torino Porta Susatrain train Fr
    2. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    9h 34m
  2. Bus

    cheapest
    1. Take the bus from Lyon to Sienabus bus 516 / ...
    11h 20m
    €45–70
  3. Drive 728.4 km

    1. Drive from Lyon to Sienacar car 728.4 km
    8h 1m
    €112–162
  4. Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 39m
    €88–218
  5. Train (Trenitalia)

    1. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    9h 36m
    €92–210
  6. Bus via Florence

    1. Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus bus Itabus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    14h 9m
  7. Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LYS - BLQ
    2. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 40m
    €101–280
  8. Train to Geneva International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Lyon Part Dieu to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane plane GVA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    10h 19m
    €112–305

Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR) flights

Calendar14Weekly Planes
Duration2h 58mAverage Duration
Ticket€48Cheapest Price
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Questions & Answers

What companies run services between Lyon, France and Siena, Italy?

FlixBus operates a bus from Lyon to Siena once daily. Tickets cost €45–70 and the journey takes 11h 20m. Alternatively, you can take a train from Lyon Part Dieu to Siena via Milano Centrale and Firenze S.M.N. in around 9h 36m.

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Train operators
Bus operators

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