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How to get fromLyon to Sienaby train, bus, car or plane

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There are 8 ways to get from Lyon to Siena by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Lyon Part Dieu to Torino Porta SusatrainFr
    2. Take the train from Torino Porta Susa to Firenze S.M.N.trainFr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus131
    9h 21m
  2. Bus via Turin

    cheapest
    1. Take the bus from Lyon Lyon Perrache Bus Station to Turin Stura Bus StationbusItabus
    2. Take the bus from Turin Stura Bus Station to Siena Central Train StationbusItabus
    14h 44m
    €36–135
  3. Bus

    1. Take the bus from Lyon to Sienabus516
    11h 20m
    €65–140
  4. Drive 728.4 km

    1. Drive from Lyon to Sienacar728.4 km
    7h 57m
    €112–162
  5. Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)planeLYS - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain
    6h 46m
    €79–217
  6. Train

    1. Take the train from Lyon Part Dieu to Milano CentraletrainFr
    2. Take the train from Milano Centrale to Florence Santa Maria Novellatrain
    3. Take the train from Firenze S.M.N. to SienatrainRe
    9h 58m
    €88–222
  7. Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)planeLYS - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 35m
    €90–294
  8. Train to Geneva International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Lyon Part Dieu to Genevetrain
    2. Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)planeGVA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    10h 26m
    €108–346

Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR) flights

Calendar12Weekly Planes
Duration2h 48mAverage Duration
Ticket€45Cheapest Price
See schedules

Questions & Answers

What companies run services between Lyon, France and Siena, Italy?

FlixBus operates a bus from Lyon to Siena 4 times a week. Tickets cost €65–140 and the journey takes 11h 20m. Alternatively, you can take a train from Lyon Part Dieu to Siena via Milano Centrale and Firenze S.M.N. in around 9h 58m.

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Bus operators

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