There are 9 ways to get from Lyon to Siena by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
8h 40m€96–198Bus
cheapest- Take the bus from Lyon to Sienabus 516 / ...
11h 20m€55–95Drive 728.1 km
- Drive from Lyon to Sienacar 728.1 km
8h 1m€116–167Fly Lyon–Saint Exupéry Airport to Florence Peretola Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane LYS - FLR
- Take the train from Firenze Rifredi to Sienatrain
6h 2m€103–256Train via Turin
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
8h 59m€104–210Bus via Florence
- Take the bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Stationbus Itabus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
14h 16m€56–97Fly Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane LYS - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
6h 48m€101–275Train to Geneva International Airport, fly to Florence Peretola Airport, train
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Florence Peretola Airport (FLR)plane GVA - FLR
- Take the train from Firenze Rifredi to Sienatrain
9h 47m€136–343Fly Lyon–Saint Exupéry Airport to Venice Marco Polo Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Venice Marco Polo Airport (VCE)plane LYS - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 27m€98–297
Lyon to Siena by train
Questions & Answers
The cheapest way to get from Lyon to Siena is to bus via Florence which costs €55 - €100 and takes 14h 16m.
The fastest way to get from Lyon to Siena is to fly and train which takes 6h 2m and costs €100 - €260.
Yes, there is a direct bus departing from Lyon and arriving at Siena. Services depart once daily, and operate Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The journey takes approximately 11h 20m.
No, there is no direct train from Lyon to Siena. However, there are services departing from Lyon Part Dieu and arriving at Siena via Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 8h 40m.
The distance between Lyon and Siena is 842 km. The road distance is 728.1 km.
The best way to get from Lyon to Siena without a car is to train which takes 8h 40m and costs €95 - €200.
It takes approximately 8h 40m to get from Lyon to Siena, including transfers.
Lyon to Siena bus services, operated by FlixBus, depart from Lyon station.
Lyon to Siena train services, operated by Trenitalia, depart from Lyon Part Dieu station.
The best way to get from Lyon to Siena is to train which takes 8h 40m and costs €95 - €200. Alternatively, you can bus, which costs €55 - €95 and takes 11h 20m.
What companies run services between Lyon, France and Siena, Italy?
You can take a train from Lyon Part Dieu to Siena via Milano Centrale and Firenze S.M.N. in around 8h 40m. Alternatively, FlixBus operates a bus from Lyon to Siena once daily. Tickets cost €55–95 and the journey takes 11h 20m.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €75–410
Flights from Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 26m
- When
- Every day
- Estimated price
- €55–380
Flights from Geneva International Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €240–1,000
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 4h 30m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €120–320
Flights from Lyon–Saint Exupéry Airport to Venice Marco Polo Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €100–390
- Website
- swiss.com
Flights from Geneva International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- €100–200
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- €90–320
- Website
- volotea.com
Flights from Lyon–Saint Exupéry Airport to Florence Peretola Airport
- Ave. Duration
- 1h 20m
- When
- Friday
- Estimated price
- €60–200
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- €90–320
Flights from Lyon–Saint Exupéry Airport to Venice Marco Polo Airport
- Ave. Duration
- 1h 20m
- When
- Monday
- Estimated price
- €35–110
- Website
- ita-airways.com
Flights from Geneva International Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- €90–320
Flights from Geneva International Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €100–200
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €500–850
- Website
- easyjet.com
Flights from Lyon–Saint Exupéry Airport to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Tuesday and Friday
- Estimated price
- €35–190
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €55–90
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze Rifredi to Siena
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- €11–18
- Website
- https://www.trenitalia.com/en.html
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- 4 times a day
- Estimated price
- €35–65
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze Rifredi to Siena
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- €11–18
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Every 30 minutes
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Every 30 minutes
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €65–130
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–26
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €35–70
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- 4 times a day
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- 4 times a day
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 58m
- Frequency
- Twice daily
- Estimated price
- €35–75
- Website
- https://www.italotreno.it/en
Train from Torino Porta Susa to Firenze S.M.N.
- Ave. Duration
- 3h 23m
- Frequency
- Once daily
- Estimated price
- €55–110
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 3 times a day
- Estimated price
- €11–22
- Website
- https://www.italotreno.it/en
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €27–55
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Lyon to Siena
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- €55–95
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Lyon Lyon Perrache Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 12h 5m
- Frequency
- Twice daily
- Estimated price
- €45–90
- Website
- https://www.itabus.it/en/home
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
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More Questions & Answers
Lyon to Siena bus services, operated by FlixBus, arrive at Siena station.
Lyon to Siena train services, operated by Trenitalia, arrive at Milano Centrale station.
Yes, the driving distance between Lyon to Siena is 728 km. It takes approximately 8h 1m to drive from Lyon to Siena.
Book your Lyon to Siena train tickets online with Omio.
Book your Lyon to Siena bus tickets online with Omio and FlixBus.
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