There are 7 ways to get from Lyon to Segrate by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
5h 36m€59–95Bus
cheapest- Take the bus from Lyon Lyon Perrache Bus Station to Milan Lampugnanobus Itabus
7h 49m€31–64Drive 445.9 km
- Drive from Lyon to Segratecar 445.9 km
4h 42m€70–101Fly Lyon–Saint Exupéry Airport to Milan Linate Airport
- Fly from Lyon–Saint Exupéry Airport (LYS) to Milan Linate Airport (LIN)plane LYS - LIN
6h 30m€107–258Bus via Lyon
- Take the bus from Lyon to Milano, Autostazione Lampugnanobus N406 / ...
8h 14m€31–73Fly Lyon–Saint Exupéry Airport to Milano Malpensa Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Milano Malpensa Airport (MXP)plane LYS - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain
5h 13m€77–215Train to Geneva International Airport, fly to Milano Malpensa Airport, train
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Milano Malpensa Airport (MXP)plane GVA - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain
7h 13m€105–279
Lyon to Segrate by train and bus (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Lyon to Segrate is to bus which costs €30 - €65 and takes 7h 49m.
The fastest way to get from Lyon to Segrate is to drive which takes 4h 42m and costs €65 - €100.
No, there is no direct bus from Lyon station to Segrate. However, there are services departing from Lyon Lyon Perrache Bus Station and arriving at via cassanese via giovanni xxiii via P.za Aspromonte. The journey, including transfers, takes approximately 7h 49m.
No, there is no direct train from Lyon to Segrate. However, there are services departing from Lyon Part Dieu and arriving at Milano Lambrate via Milano Centrale. The journey, including transfers, takes approximately 5h 36m.
The distance between Lyon and Segrate is 456 km. The road distance is 445.9 km.
The best way to get from Lyon to Segrate without a car is to train which takes 5h 36m and costs €55 - €100.
It takes approximately 5h 36m to get from Lyon to Segrate, including transfers.
Lyon to Segrate bus services, operated by Itabus S.p.A., depart from Lyon Lyon Perrache Bus Station.
Lyon to Segrate train services, operated by Trenitalia, depart from Lyon Part Dieu station.
The best way to get from Lyon to Segrate is to train which takes 5h 36m and costs €55 - €100. Alternatively, you can bus, which costs €30 - €65 and takes 7h 49m, you could also fly, which costs €100 - €260 and takes 6h 30m.
What companies run services between Lyon, France and Segrate, Italy?
Trenitalia operates a train from Lyon Part Dieu to Milano Centrale twice daily. Tickets cost €55–90 and the journey takes 4h 44m. Alternatively, Itabus S.p.A. operates a bus from Lyon Lyon Perrache Bus Station to Milan Lampugnano once daily. Tickets cost €27–60 and the journey takes 6h 50m.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- €85–650
Flights from Lyon–Saint Exupéry Airport to Milan Linate Airport via Munich
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €85–280
- Website
- airfrance.com
Flights from Lyon–Saint Exupéry Airport to Milan Linate Airport via Paris Charles de Gaulle
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- €60–340
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Milano Malpensa Airport
- Ave. Duration
- 1h
- When
- Monday to Friday
- Estimated price
- €480–750
- Website
- swiss.com
Flights from Geneva International Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 2h 42m
- When
- Every day
- Estimated price
- €80–280
- Website
- gulfair.com
Flights from Geneva International Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 5m
- When
- Tuesday and Friday
- Estimated price
- €120–180
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €55–90
- Website
- Trenitalia
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Milano Porta Garibaldi
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Milano Porta Garibaldi
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Every 3 hours
- Estimated price
- €26–55
- Website
- Oui.SNCF
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- €30–55
- Website
- TGV inOui
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Lyon Lyon Perrache Bus Station to Milan Lampugnano
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- €27–60
- Website
- Itabus S.p.A.
Bus from Lyon to Milano, Autostazione Lampugnano
- Ave. Duration
- 6h 50m
- Frequency
- 4 times a day
- Estimated price
- €27–60
- Website
- Itabus S.p.A.
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Lyon to Milano, Autostazione Lampugnano
- Ave. Duration
- 6h 5m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Lyon to Milano, Autostazione Lampugnano
- Ave. Duration
- 7h 45m
- Frequency
- Hourly
- Estimated price
- €35–70
- Website
- BlaBlaCar Bus
Want to know more about travelling around Italy
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Booking & Getting There
Lyon to Segrate bus services, operated by Itabus S.p.A., arrive at Milan Lampugnano station.
Lyon to Segrate train services, operated by Trenitalia, arrive at Milano Centrale station.
Yes, the driving distance between Lyon to Segrate is 446 km. It takes approximately 4h 42m to drive from Lyon to Segrate.
There are 14087+ hotels available in Segrate.




























