Explore 4 ways to travel

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Lyon  •  4 h 51 min

  1. Fly from Lyon (LYS) to Prague (PRG) LYS - PRG

$89 - $270

Cheapest option

Bus RegioJet  •  17 h 10 min

  1. Take the bus from Lyon, de Perrache - Galerie C to Praha, Wilsonova Rj

$40 - $190

5 alternative options

Train to Geneva, fly  •  6 h 27 min

  1. Take the train from Lyon Part Dieu to Geneve
  2. Fly from Geneva (GVA) to Prague (PRG) GVA - PRG

$99 - $309

Train TGV  •  13 h 9 min

  1. Take the train from Lyon Part Dieu to Frankfurt(Main)Hbf Tgv
  2. Take the train from Frankfurt(Main)Hbf to Nürnberg Hbf Ice / ...
  3. Take the train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)

$231 - $294

Bus Tour Bus  •  16 h 34 min

  1. Take the bus from Lyon to Lausanne
  2. Take the bus from Lausanne to Prague 000259

$94 - $154

Train EuroNight  •  19 h 21 min

  1. Take the train from Lyon Part Dieu to Geneve Tgv / ...
  2. Take the train from Genève to Zürich HB 1 / ...
  3. Take the train from Zürich HB to Praha hl.n. En

Drive  •  9 h 30 min

  1. Drive from Lyon to Prague 676 miles

$140 - $210

What companies run services between Lyon, France and Prague, Czech Republic?

Hop!, Lufthansa and four other airlines fly from Lyon to Prague every 2 hours. Alternatively, you can take a train from Lyon to Prague via Frankfurt(Main)Hbf, Nürnberg Hbf, and Nürnberg ZOB in around 13 h 9 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Lyon to Prague via Munich
Ave. Duration
3 h 25 min
When
Every day
Estimated price
$170 - $800
Flights from Lyon to Prague via Frankfurt
Ave. Duration
3 h 38 min
When
Every day
Estimated price
$170 - $800
Flights from Geneva to Prague via Munich
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$160 - $950
Flights from Geneva to Prague via Frankfurt
Ave. Duration
3 h 28 min
When
Every day
Estimated price
$160 - $950
Air France
Website
airfrance.com
Flights from Lyon to Prague
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$180 - $850
Flights from Lyon to Prague via Paris CDG
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$150 - $650
Flights from Geneva to Prague via Paris CDG
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$95 - $390
Swiss
Website
swiss.com
Flights from Geneva to Prague
Ave. Duration
1 h 30 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $370
Flights from Geneva to Prague via Zurich
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$70 - $370
Austrian Airlines
Website
austrian.com
Flights from Lyon to Prague via Vienna
Ave. Duration
3 h 55 min
When
Monday to Friday
Estimated price
$170 - $900
Flights from Geneva to Prague via Vienna
Ave. Duration
3 h 35 min
When
Monday to Saturday
Estimated price
$160 - $950
Hop!
Website
hop.com
Flights from Lyon to Prague
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$180 - $850
KLM
Website
klm.com
Flights from Lyon to Prague via Amsterdam
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$150 - $700
Flybe
Website
flybe.com
Flights from Lyon to Prague via Southend
Ave. Duration
4 h 25 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$75 - $1,100
Brussels Airlines
Website
brusselsairlines.com
Flights from Geneva to Prague via Brussels
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$85 - $430
Train operators
SNCF
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Lyon Part Dieu to Geneve
Ave. Duration
1 h 54 min
Frequency
Every 2 hours
Estimated price
$30 - $50
Website
en.oui.sncf
TGV
Phone
0033 892 353535
Website
tgv.com
Train from Lyon Part Dieu to Geneve
Ave. Duration
1 h 44 min
Frequency
Twice daily
Estimated price
$35 - $45
Website
en.oui.sncf
2nd Class
$35 - $45
1st Class
$55 - $70
Train from Lyon Part Dieu to Frankfurt(Main)Hbf
Ave. Duration
5 h 58 min
Frequency
Once daily
Estimated price
$140 - $160
Website
en.oui.sncf
2nd Class
$140 - $160
1st Class
$180 - $270
Swiss Railways (SBB/CFF/FFS)
Website
sbb.ch
Train from Lyon-Part-Dieu to Genève
Ave. Duration
1 h 57 min
Frequency
Twice daily
Estimated price
$50 - $95
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Train from Genève to Zürich HB
Ave. Duration
2 h 46 min
Frequency
Hourly
Estimated price
$85 - $150
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Frankfurt(Main)Hbf to Nürnberg Hbf
Ave. Duration
2 h 4 min
Frequency
Hourly
Estimated price
$50 - $75
Website
bahn.de
Train from Nürnberg ZOB to Praha hl.n. (Autobusová St. Wilsonova)
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
bahn.de
EuroNight
Website
cd.cz
Train from Zürich HB to Praha hl.n.
Ave. Duration
13 h 17 min
Frequency
3 times a day
Website
cd.cz
Bus operators
Eurolines CH
Phone
0041 (0) 844 257 224
Website
eurolines.ch
Bus from Lyon to Lausanne
Ave. Duration
3 h 30 min
Frequency
3 times a week
Estimated price
$25 - $30
Book at
eurolines.ch
Tour Bus
Website
tourbus.cz
Bus from Lausanne to Prague
Ave. Duration
11 h 48 min
Frequency
3 times a week
Estimated price
$65 - $120
Schedules at
tourbus.cz
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Lyon, de Perrache - Galerie C to Praha, Wilsonova
Ave. Duration
17 h 10 min
Frequency
3 times a week
Estimated price
$40 - $55
Schedules at
regiojet.sk
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Lyon to Prague
Ave. Duration
17 h 30 min
Frequency
3 times a week
Estimated price
$130 - $190
Schedules at
eurolines.fr
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Lyon to Praha ÚAN Florenc
Ave. Duration
19 h 30 min
Frequency
Twice a week
Estimated price
$45 - $95
Schedules at
elines.cz

Want to know more about travelling around Czechia

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Lyon and Prague is 860 km. The road distance is 1082 km.

The cheapest way to get from Lyon to Prague is to fly which costs 75€ - 230€ and takes 4 h 51 min.

The quickest way to get from Lyon to Prague is to fly which takes 4 h 51 min and costs 75€ - 230€.

No, there is no direct train from Lyon to Prague. However, there are services departing from Lyon Part Dieu and arriving at Praha hl.n. (Autobusová St. Wilsonova) via Frankfurt(Main)Hbf and Nürnberg ZOB. The journey, including transfers, takes approximately 13 h 9 min.

Yes, there is a direct bus departing from Lyon, de Perrache - Galerie C and arriving at Praha, Wilsonova. Services depart five times a week, and operate Tuesday, Wednesday, Friday, Saturday and Sunday. The journey takes approximately 17 h 10 min.

It takes approximately 4 h 51 min to get from Lyon to Prague, including transfers.