There are 10 ways to get from Lyon to Palermo by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Lyon–Saint Exupéry Airport
best- Fly from Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO)plane LYS - PMO
5h 33m€74–282Train to Turin Caselle Airport, fly
cheapest- Take the train from Lyon Part Dieu to Torino Porta Susatrain
- Fly from Turin Caselle Airport (TRN) to Palermo Airport (PMO)plane TRN - PMO
8h 24m€60–248Train, ferry
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
20h 27mDrive, car ferry
- Drive from Lyon to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
25h 33m€183–265Bus, ferry
- Take the bus from Lyon Lyon Perrache Bus Station to Naples Metropark Central Parkingbus Itabus
- Take the ferry from Naples Beverello to Port of Palermoferry
27h 49m€107–207Train to Geneva International Airport, fly
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Palermo Airport (PMO)plane GVA - PMO
7h 23m€86–393Train to Marseille Provence Airport, fly
- Take the train from Lyon Part Dieu to Aix En Provence Tgvtrain
- Fly from Marseille Provence Airport (MRS) to Palermo Airport (PMO)plane MRS - PMO
6h 38m€98–334Train
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
20h 33m€215–415Train, car ferry
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Lingotto to Genova P.Za Principetrain
- Take the carferry from Port of Genoa to Port of Palermocarferry
28h 51m€165–265Bus
- Take the bus from Lyon - Gerland Bus Station to Turin - Vittorio Emanuele Bus Stationbus BlaBlaCar Bus
- Take the bus from Turin to Palermobus N597
29h 21m€154–262
Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Lyon to Palermo is to train and fly which costs €60 - €250 and takes 8h 24m.
The fastest way to get from Lyon to Palermo is to fly which takes 5h 33m and costs €70 - €290.
No, there is no direct bus from Lyon station to Palermo. However, there are services departing from Lyon - Gerland Bus Station and arriving at Palermo via Turin. The journey, including transfers, takes approximately 29h 21m.
No, there is no direct train from Lyon to Palermo. However, there are services departing from Lyon Part Dieu and arriving at Palermo Centrale via Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 20h 33m.
The distance between Lyon and Palermo is 1120 km.
The best way to get from Lyon to Palermo without a car is to train and ferry which takes 20h 27m and costs .
It takes approximately 5h 33m to get from Lyon to Palermo, including transfers.
Lyon to Palermo bus services, operated by BlaBlaCar Bus, depart from Lyon - Gerland Bus Station.
Lyon to Palermo train services, operated by Trenitalia, depart from Lyon Part Dieu station.
The best way to get from Lyon to Palermo is to fly which takes 5h 33m and costs €70 - €290. Alternatively, you can train, which costs €210 - €420 and takes 20h 33m, you could also bus, which costs €150 - €270 and takes 29h 21m.
What companies run services between Lyon, France and Palermo, Italy?
Volotea, easyJet, and Transavia France fly from Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO) 6 times a week. Alternatively, you can take a train from Lyon Part Dieu to Palermo Centrale via Milano Centrale and Roma Termini in around 20h 33m.
- Website
- ryanair.com
Flights from Turin Caselle Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €35–190
Flights from Turin Caselle Airport to Palermo Airport via Cagliari
- Ave. Duration
- 4h
- When
- Monday
- Estimated price
- €35–190
Flights from Marseille Provence Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- €45–210
Flights from Marseille Provence Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 5m
- When
- Thursday, Monday, and Saturday
- Estimated price
- €45–210
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- Trenitalia
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Estimated price
- €27–45
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €55–85
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- Trenitalia
Train from Torino Lingotto to Genova P.Za Principe
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €19–30
- Website
- Trenitalia
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Lyon Lyon Perrache Bus Station to Naples Metropark Central Parking
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €75–150
- Website
- Itabus S.p.A.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
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More Questions & Answers
Lyon to Palermo bus services, operated by BlaBlaCar Bus, arrive at Turin - Vittorio Emanuele Bus Station.
Lyon to Palermo train services, operated by Trenitalia, arrive at Milano Centrale station.
Book your Lyon to Palermo train tickets online with Omio.
Book your Lyon to Palermo bus tickets online with Omio and FlixBus.
There are 6293+ hotels available in Palermo.




