There are 5 ways to get from Lyon to Issenheim by train, bus, car, plane, or train (TGV)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Lyon Part Dieu to Mulhouse Villetrain 84
5h 25m€56–82Bus
cheapest- Take the bus from Lyon - Perrache Bus Station to Mulhousebus BlaBlaCar Bus
7h 24m€31–56Drive 366.8 km
- Drive from Lyon to Issenheimcar 366.8 km
3h 58m€57–82Fly, train, bus
- Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane LYS - SXB
- Take the train from Strasbourg to Colmartrain
- Take the train from Colmar to Rouffachtrain
- Take the bus from ROUFFACH - Gare SNCF to ISSENHEIM - Mairiebus
6h 8m€124–273Train via Rouffach (TGV)
- Take the train from Lyon Part Dieu to Mulhouse Villetrain Tgv
5h 36m€57–263
Lyon to Issenheim by train, tram, and bus
Questions & Answers
The cheapest way to get from Lyon to Issenheim is to bus which costs €30 - €60 and takes 7h 24m.
The fastest way to get from Lyon to Issenheim is to drive which takes 3h 58m and costs €55 - €85.
No, there is no direct bus from Lyon station to Issenheim. However, there are services departing from Lyon - Perrache Bus Station and arriving at ISSENHEIM - Mairie via MULHOUSE - Gare Centrale and GUEBWILLER - Piscine. The journey, including transfers, takes approximately 7h 24m.
The distance between Lyon and Issenheim is 416 km. The road distance is 366.8 km.
The best way to get from Lyon to Issenheim without a car is to train which takes 5h 25m and costs €55 - €85.
It takes approximately 5h 25m to get from Lyon to Issenheim, including transfers.
Lyon to Issenheim bus services, operated by BlaBlaCar Bus, depart from Lyon - Perrache Bus Station.
The best way to get from Lyon to Issenheim is to train which takes 5h 25m and costs €55 - €85. Alternatively, you can bus, which costs €30 - €60 and takes 7h 24m.
Lyon to Issenheim bus services, operated by BlaBlaCar Bus, arrive at Mulhouse station.
Yes, the driving distance between Lyon to Issenheim is 367 km. It takes approximately 3h 58m to drive from Lyon to Issenheim.
What companies run services between Lyon, France and Issenheim, France?
Société Nationale des Chemins de fer Français (SNCF) operates a train from Lyon Part Dieu to Mulhouse Ville once daily. Tickets cost €50–80 and the journey takes 2h 49m. Deutsche Bahn Intercity (DB IC) also services this route 4 times a week. Alternatively, BlaBlaCar Bus operates a bus from Lyon - Perrache Bus Station to Mulhouse once daily. Tickets cost €25–50 and the journey takes 5h. FlixBus also services this route once a week.
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Strasbourg International Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Friday
- Estimated price
- €480–950
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Mulhouse Ville
- Ave. Duration
- 2h 49m
- Frequency
- Once daily
- Estimated price
- €50–80
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Strasbourg to Colmar
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €15–16
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Colmar to Rouffach
- Ave. Duration
- 10 min
- Frequency
- Hourly
- Estimated price
- €3–4
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Lyon Part Dieu to Mulhouse Ville
- Ave. Duration
- 2h 46m
- Frequency
- 4 times a week
- Estimated price
- €65–75
- Website
- https://int.bahn.de/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Strasbourg to Colmar
- Ave. Duration
- 29 min
- Frequency
- 5 times a day
- Estimated price
- €9–17
- Website
- https://www.sncf-connect.com/en-en
Train from Lyon Part Dieu to Mulhouse Ville
- Ave. Duration
- 3h 8m
- Frequency
- Every 4 hours
- Estimated price
- €45–260
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Lyon - Perrache Bus Station to Mulhouse
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- €25–50
- Website
- https://www.blablacar.co.uk/bus
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lyon - Perrache Bus Station to Mulhouse
- Ave. Duration
- 5h 25m
- Frequency
- Once a week
- Estimated price
- €29–45
- Website
- https://www.flixbus.co.uk
- Phone
- 03 89 29 30 40
- Website
- fluo.eu
Bus from ROUFFACH - Gare SNCF to ISSENHEIM - Mairie
- Ave. Duration
- 22 min
- Frequency
- Every 3 hours
- Estimated price
- €3
- Schedules at
- fluo.grandest.fr
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
There are 858+ hotels available in Issenheim.


























