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How to get fromLucerne to Sienaby train (Trenitalia), bus, car, train, or plane

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There are 6 ways to get from Lucerne to Siena by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Luzern to Luganotrain train Ec / ...
    2. Take the train from Lugano to Milano Centraletrain train
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    7h 47m
    €130–368

  2. Bus via Lugano

    cheapest
    1. Take the bus from Lucerne Landenbergstrasse to Lugano Via Giacomo and Filippo Cianibus bus
    2. Take the bus from Lugano Via Giacomo and Filippo Ciani to Florence - Villa Costanzabus bus 36
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    12h 46m
    €45–76

  3. Bus

    1. Take the bus from Luzern to Bolognabus bus FlixBus 439
    2. Take the bus from Bologna Centrale to Sienabus bus N597 / ...
    10h 15m
    €46–81

  4. Drive 604.5 km

    1. Drive from Lucerne to Sienacar car 604.5 km
    6h 13m
    €107–155

  5. Train, fly to Florence Peretola Airport

    1. Take the train from Luzern to Zürich HBtrain train
    2. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 40m
    €137–341

  6. Train, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Luzern to Zürich HBtrain train
    2. Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane plane ZRH - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    6h 55m
    €134–326

Lucerne to Siena by train

Calendar70Weekly Trains
Duration7h 47mAverage Duration
Ticket€130Cheapest Price
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Questions & Answers

Map of how to get from Lucerne to Siena.ExpandLaunch map view
  • Distance: 633.5 km
  • Duration: 7h 47m

What companies run services between Lucerne, Switzerland and Siena, Italy?

You can take a train from Luzern to Siena via Lugano, Milano Centrale, and Firenze S.M.N. in around 7h 47m. Alternatively, you can take a bus from Luzern to Siena via Bologna and Bologna Centrale in around 10h 15m.

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