There are 7 ways to get from Luthern to Siena by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Luzern to LuganoEc / ...
- Take the train from Lugano to Milano CentraleEc
- Take the train from Milano Centrale to Firenze S.M.N.Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzi131
8h 26mBus
cheapest- Take the bus from Luzern to Florence Villa Constanza Bus Station1524
- Take the bus from Florence Villa Constanza Bus Station to SienaN528 / ...
11h 1m€42–108Drive 604.2 km
- Drive from Luthern to Siena604.2 km
6h 11m€104–150Train, fly to Florence Peretola Airport
- Take the train from Luzern to Zürich HB
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)ZRH - FLR
- Take the train from Firenze S.M.N. to Siena
6h 56m€104–312Train
- Take the train from Luzern to LuganoEc / ...
- Take the train from Lugano to Milano CentraleEc
- Take the train from Milano Centrale to Florence Santa Maria Novella
- Take the train from Firenze S.M.N. to SienaRe
8h 38m€80–170Bus via Lugano
- Take the bus from Lucerne to Lugano
- Take the bus from Lugano Via Giacomo and Filippo Ciani to Siena Central Train StationItabus
12h 15m€42–73Train, fly to Bologna Guglielmo Marconi Airport
- Take the train from Luzern to Zürich HB
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)ZRH - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Siena
7h 30m€115–349
Zurich Airport (ZRH) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Luthern to Siena is to bus via Lugano which costs €40 - €75 and takes 12h 15m.
The fastest way to get from Luthern to Siena is to drive which takes 6h 11m and costs €100 - €150.
No, there is no direct bus from Luthern to Siena. However, there are services departing from Luzern and arriving at Siena via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 11h 1m.
No, there is no direct train from Luthern to Siena. However, there are services departing from Luzern and arriving at Siena via Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 8h 38m.
The distance between Luthern and Siena is 611 km. The road distance is 604.2 km.
The best way to get from Luthern to Siena without a car is to train and bus which takes 8h 26m and costs .
It takes approximately 8h 26m to get from Luthern to Siena, including transfers.
Luthern to Siena bus services, operated by FlixBus, depart from Luzern station.
Luthern to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Luzern station.
The best way to get from Luthern to Siena is to bus which takes 11h 1m and costs €40 - €110. Alternatively, you can train, which costs €80 - €170 and takes 8h 38m.
What companies run services between Luthern, Switzerland and Siena, Italy?
You can take a bus from Luzern to Siena via Florence Villa Constanza Bus Station in around 11h 1m. Alternatively, you can take a train from Luzern to Siena via Lugano, Milano Centrale, and Firenze S.M.N. in around 8h 38m.
- Website
- swiss.com
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €90–200
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €80–420
- Website
- lufthansa.com
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €130–430
- Website
- airdolomiti.it
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 10m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €130–430
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Luzern to Lugano
- Ave. Duration
- 1h 40m
- Frequency
- Every 2 hours
- Estimated price
- €40–75
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €23–45
- Website
- https://www.sbb.ch/en
Train from Luzern to Zürich HB
- Ave. Duration
- 42 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Website
- https://www.sbb.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 18m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €35–85
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €25–65
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Florence Santa Maria Novella
- Ave. Duration
- 1h 55m
- Frequency
- Every 2 hours
- Estimated price
- €29–80
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €15–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Luzern to Florence Villa Constanza Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- 6 times a week
- Estimated price
- €35–85
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–15
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €7–26
- Website
- https://www.itabus.it/en/home
Bus from Lugano Via Giacomo and Filippo Ciani to Siena Central Train Station
- Ave. Duration
- 8h 20m
- Frequency
- Twice daily
- Estimated price
- €25–50
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–14
- Website
- https://marinobus.it/en/
- Phone
- +39 0827 34 117
- info@gruppodimaio.it
- Website
- gruppodimaio.it
Bus from Lucerne to Lugano
- Ave. Duration
- 2h 45m
- Frequency
- Twice a week
- Estimated price
- €14–20
- Schedules at
- gruppodimaio.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Italian Lakes: Getting around by train
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
More Questions & Answers
Luthern to Siena bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Luthern to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Lugano station.
Yes, the driving distance between Luthern to Siena is 604 km. It takes approximately 6h 11m to drive from Luthern to Siena.
Book your Luthern to Siena train tickets online with Omio.
Book your Luthern to Siena bus tickets online with Omio and FlixBus.
There are 2200+ hotels available in Siena.












































