There are 6 ways to get from Luthern to Siena by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Luzern to Luganotrain Ec / ...
- Take the train from Lugano to Milano Centraletrain Ec
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
7h 49mBus
cheapest- Take the bus from Luzern to Florence Villa Constanza Bus Stationbus 1524
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
10h 57m€42–91Drive 604.2 km
- Drive from Luthern to Sienacar 604.2 km
6h 13m€105–151Train, fly to Florence Peretola Airport
- Take the train from Luzern to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 49m€113–303Train, bus via Cadenazzo
- Take the train from Luzern to Cadenazzotrain
- Take the train from Cadenazzo to Milano Centraletrain
- Take the train from Milano Centrale to Florence Santa Maria Novellatrain
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
9h 55mTrain, fly to Bologna Guglielmo Marconi Airport
- Take the train from Luzern to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane ZRH - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
7h 36m€127–315
Zurich Airport (ZRH) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Luthern to Siena is to bus which costs €40 - €95 and takes 10h 57m.
The fastest way to get from Luthern to Siena is to drive which takes 6h 13m and costs €100 - €160.
No, there is no direct bus from Luthern to Siena. However, there are services departing from Luzern and arriving at Siena via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 10h 57m.
The distance between Luthern and Siena is 611 km. The road distance is 604.2 km.
The best way to get from Luthern to Siena without a car is to train and bus which takes 7h 49m and costs .
It takes approximately 7h 49m to get from Luthern to Siena, including transfers.
Luthern to Siena bus services, operated by FlixBus, depart from Luzern station.
Luthern to Siena bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Yes, the driving distance between Luthern to Siena is 604 km. It takes approximately 6h 13m to drive from Luthern to Siena.
Book your Luthern to Siena bus tickets online with Omio and FlixBus.
What companies run services between Luthern, Switzerland and Siena, Italy?
You can take a bus from Luzern to Siena via Florence Villa Constanza Bus Station in around 10h 57m.
- Website
- swiss.com
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €75–210
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €80–420
- Website
- lufthansa.com
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €110–370
- Website
- airdolomiti.it
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 10m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €110–370
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Luzern to Lugano
- Ave. Duration
- 1h 40m
- Frequency
- Every 2 hours
- Estimated price
- €35–75
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €23–45
- Website
- https://www.sbb.ch/en
Train from Luzern to Zürich HB
- Ave. Duration
- 42 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €23–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 58 580 70 70
- info@sob.ch
- Website
- sob.ch
Train from Luzern to Cadenazzo
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Schedules at
- sob.ch
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Cadenazzo to Milano Centrale
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Florence Santa Maria Novella
- Ave. Duration
- 1h 55m
- Frequency
- Every 2 hours
- Estimated price
- €29–70
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Luzern to Florence Villa Constanza Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- 6 times a week
- Estimated price
- €35–75
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–16
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- €6–16
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–13
- Website
- https://marinobus.it/en/
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