There are 11 ways to get from Lucerne to Palermo by train, plane, ferry, car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Zurich Airport, fly
best- Take the train from Luzern to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Palermo Airport (PMO)plane ZRH - PMO
6h€106–365Bus
cheapest- Take the bus from Luzern to Milanbus FlixBus N401 / ...
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
26h 15m€77–218Train, ferry
- Take the train from Luzern to Luganotrain Ec / ...
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Villa S.Giovannitrain
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
19h 48mDrive, car ferry
- Drive from Lucerne to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
24h 52m€157–237Train, bus
- Take the train from Luzern to Luganotrain Ec / ...
- Take the train from Lugano to Milano Centraletrain
- Take the bus from Milano, San Donato M3 to Palermo Via Tommaso Fazellobus
26h 3m€123–264Train, train to Milan Linate Airport, fly
- Take the train from Luzern to Luganotrain
- Take the train from Lugano to Seregnotrain
- Fly from Milan Linate Airport (LIN) to Palermo Airport (PMO)plane LIN - PMO
7h 36m€130–371Train, train to Milano Malpensa Airport, fly
- Take the train from Luzern to Luganotrain
- Take the train from Lugano to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Palermo Airport (PMO)plane MXP - PMO
7h 44m€95–313Train to Basel, fly
- Take the train from Luzern to Basel SBBtrain
- Fly from Basel (BSL) to Palermo Airport (PMO)plane BSL - PMO
6h 26m€79–319Train, bus to Il Caravaggio International Airport, fly
- Take the train from Luzern to Luganotrain
- Take the train from Lugano to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Bergamo Airport Bus Stationbus
- Fly from Il Caravaggio International Airport (BGY) to Palermo Airport (PMO)plane BGY - PMO
8h 16m€140–600Train
- Take the train from Luzern to Luganotrain Ec / ...
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
19h 58m€248–598Train, car ferry
- Take the train from Luzern to Luganotrain Ec / ...
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Genova P.Za Principetrain Ic
- Take the car ferry from Port of Genoa to Port of Palermocarferry
27h 48m€192–428
Zurich Airport (ZRH) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Lucerne to Palermo is to bus which costs €75 - €220 and takes 26h 15m.
The fastest way to get from Lucerne to Palermo is to train and fly which takes 6h and costs €100 - €370.
No, there is no direct bus from Lucerne to Palermo. However, there are services departing from Luzern and arriving at Palermo via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 26h 15m.
No, there is no direct train from Lucerne to Palermo. However, there are services departing from Luzern and arriving at Palermo Centrale via Lugano, Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 19h 58m.
The distance between Lucerne and Palermo is 1190 km.
The best way to get from Lucerne to Palermo without a car is to train and ferry which takes 19h 48m and costs .
It takes approximately 6h to get from Lucerne to Palermo, including transfers.
Lucerne to Palermo bus services, operated by FlixBus, depart from Luzern station.
Lucerne to Palermo train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Luzern station.
The best way to get from Lucerne to Palermo is to train which takes 19h 58m and costs €240 - €600. Alternatively, you can bus, which costs €75 - €220 and takes 26h 15m.
What companies run services between Lucerne, Switzerland and Palermo, Italy?
You can take a train from Luzern to Palermo Centrale via Lugano, Milano Centrale, and Roma Termini in around 19h 58m. Alternatively, you can take a bus from Luzern to Palermo via Milano, Autostazione Lampugnano in around 26h 15m.
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €45–130
Flights from Il Caravaggio International Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €45–320
- Website
- ita-airways.com
Flights from Zurich Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- €70–360
Flights from Milan Linate Airport to Palermo Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €55–130
Flights from Milan Linate Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- €55–130
- Website
- easyjet.com
Flights from Zurich Airport to Palermo Airport via Naples
- Ave. Duration
- 4h 50m
- When
- Monday
- Estimated price
- €90–420
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €45–140
Flights from Basel to Palermo Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €35–240
- Website
- swiss.com
Flights from Zurich Airport to Palermo Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- €95–360
Flights from Zurich Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- €70–360
- Website
- flyulendo.com
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €12–120
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Luzern to Zürich HB
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €20–60
- Website
- https://www.sbb.ch/en
Train from Luzern to Lugano
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- €55–170
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €28–80
- Website
- https://www.sbb.ch/en
Train from Lugano to Seregno
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €20–60
- Website
- https://www.sbb.ch/en
Train from Luzern to Basel SBB
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €30–100
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Villa S.Giovanni
- Ave. Duration
- 10h 3m
- Frequency
- Once daily
- Estimated price
- €150–310
- Website
- https://www.italotreno.it/en
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- €70–150
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Genova P.Za Principe
- Ave. Duration
- 1h 53m
- Frequency
- Every 4 hours
- Estimated price
- €17–28
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- €23–50
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Once daily
- Estimated price
- €90–200
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Genova P.Za Principe
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €6–8
- Website
- https://www.trenord.it/en/
Train from Lugano to Seregno
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €3–4
- Website
- https://www.trenord.it/en/
Train from Lugano to Malpensa Aeroporto T1
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Website
- https://www.trenord.it/en/
- Phone
- +41 58 580 70 70
- Website
- sob.ch
Train from Luzern to Basel SBB
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Schedules at
- sob.ch
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Genova P.Za Principe
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €20–40
- Schedules at
- trenitalia.com
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Milano, San Donato M3 to Palermo Via Tommaso Fazello
- Ave. Duration
- 21h
- Frequency
- Twice a week
- Estimated price
- €55–85
- Schedules at
- autoservizisalemi.it
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 45m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- autoservizisalemi.it
- info@flibco.com
- Website
- flibco.com
Bus from Piazza Luigi di Savoia to Bergamo Airport Bus Station
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- €8–21
- Website
- https://www.flibco.com/en
- customerservices@terravision.eu
- Website
- terravision.eu
Bus from Piazza Luigi di Savoia to Bergamo Airport Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–25
- Website
- https://www.terravision.eu/
- Phone
- +39 02 3008 9000
- mail@autostradale.it
- Website
- autostradale.it
Bus from Piazza Luigi di Savoia to Bergamo Airport Bus Station
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €4–8
- Website
- https://autostradale.it/?lang=en-GB
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Luzern to Milan
- Ave. Duration
- 3h 20m
- Frequency
- 3 times a day
- Estimated price
- €16–28
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €110–190
- Website
- https://www.flixbus.co.uk
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €90–140
- Website
- https://www.gnv.it/en
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More Questions & Answers
Lucerne to Palermo bus services, operated by FlixBus, arrive at Milan station.
Lucerne to Palermo train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Lugano station.
Book your Lucerne to Palermo train tickets online with Omio.
Book your Lucerne to Palermo bus tickets online with Omio and FlixBus.
There are 6266+ hotels available in Palermo.





























































