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How to get fromLuthern to Iserniaby train (Trenitalia), bus, car, train or plane

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There are 11 ways to get from Luthern to Isernia by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Luzern to LuganotrainEc / ...
    2. Take the train from Lugano to Milano CentraletrainEc
    3. Take the train from Milano Centrale to Roma TerminitrainFr / ...
    4. Take the train from Roma Termini to IserniatrainRe
    10h 12m
    €137–299

  2. Bus via Campobasso

    cheapest
    1. Take the bus from Luthern to Campobassobus
    2. Take the bus from Campobasso Terminal Autobus to IserniabusCb 005 / ...
    15h
    €52–64

  3. Drive 966.4 km

    1. Drive from Luthern to Iserniacar966.4 km
    9h 16m
    €166–239

  4. Train to Zurich Airport, fly to Naples Airport, train

    1. Take the train from Luzern to Zürich HBtrain
    2. Fly from Zurich Airport (ZRH) to Naples Airport (NAP)planeZRH - NAP
    3. Take the train from Napoli Centrale to Iserniatrain
    7h 55m
    €89–298

  5. Bus

    1. Take the bus from Lucerne to Caianellobus
    2. Take the bus from Casello - A1 Ingresso Caianello to Iserniabus6
    15h 43m
    €79–110

  6. Train to Zurich Airport, fly to Fiumicino International Airport, train

    1. Take the train from Luzern to Zürich HBtrain
    2. Fly from Zurich Airport (ZRH) to Fiumicino International Airport (FCO)planeZRH - FCO
    3. Take the train from Roma Termini to Iserniatrain
    8h 19m
    €98–285

  7. Train to Basel, fly to Naples Airport, train

    1. Take the train from Luzern to Basel SBBtrain
    2. Fly from Basel (BSL) to Naples Airport (NAP)planeBSL - NAP
    3. Take the train from Napoli Centrale to Iserniatrain
    8h 43m
    €88–282

  8. Train, train to Milano Malpensa Airport, fly to Naples Airport

    1. Take the train from Luzern to Luganotrain
    2. Take the train from Lugano to Malpensa Aeroporto T1train
    3. Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)planeMXP - NAP
    4. Take the train from Napoli Centrale to Iserniatrain
    9h 47m
    €83–250

  9. Train, train to Milan Linate Airport, fly to Naples Airport

    1. Take the train from Luzern to Luganotrain
    2. Take the train from Lugano to Monzatrain
    3. Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)planeLIN - NAP
    4. Take the train from Napoli Centrale to Iserniatrain
    10h 4m
    €100–273

  10. Train, train to Milano Malpensa Airport, fly to Foggia Gino Lisa Airport, bus

    1. Take the train from Luzern to Luganotrain
    2. Take the train from Lugano to Malpensa Aeroporto T1train
    3. Fly from Milano Malpensa Airport (MXP) to Foggia Gino Lisa Airport (FOG)planeMXP - FOG
    4. Take the bus from Foggia to Iserniabus
    10h 7m
    €135–281

  11. Train, train to Milano Malpensa Airport, fly to Abruzzo Airport, bus

    1. Take the train from Luzern to Luganotrain
    2. Take the train from Lugano to Malpensa Aeroporto T1train
    3. Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)planeMXP - PSR
    4. Take the bus from Pescara to Iserniabus
    11h 4m
    €83–269

Luthern to Isernia by train

Calendar55Weekly Trains
Duration10h 12mAverage Duration
Ticket€137Cheapest Price
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Questions & Answers

What companies run services between Luthern, Switzerland and Isernia, Italy?

You can take a train from Luzern to Isernia via Lugano, Milano Centrale, and Roma Termini in around 10h 12m. Alternatively, you can take a bus from Luthern to Isernia via Campobasso and Campobasso Terminal Autobus in around 15h.

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