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How to get fromLuthern to Iserniaby train (Trenitalia), bus, car, train or plane

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There are 11 ways to get from Luthern to Isernia by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Luzern to Luganotrain train Ec / ...
    2. Take the train from Lugano to Milano Centraletrain train Ec
    3. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    4. Take the train from Roma Termini to Iserniatrain train Re
    10h 8m
    €118–255

  2. Bus via Campobasso

    cheapest
    1. Take the bus from Luthern to Campobassobus bus
    2. Take the bus from Campobasso Terminal Autobus to Iserniabus bus Cb 005 / ...
    15h
    €52–63

  3. Drive 966.4 km

    1. Drive from Luthern to Iserniacar car 966.4 km
    9h 20m
    €168–243

  4. Train to Zurich Airport, fly to Naples Airport, train

    1. Take the train from Luzern to Zürich HBtrain train
    2. Fly from Zurich Airport (ZRH) to Naples Airport (NAP)plane plane ZRH - NAP
    3. Take the train from Napoli Centrale to Iserniatrain train
    7h 55m
    €89–298

  5. Bus

    1. Take the bus from Lucerne to Caianellobus bus
    2. Take the bus from Casello - A1 Ingresso Caianello to Iserniabus bus 6
    15h 43m
    €79–110

  6. Train to Zurich Airport, fly to Fiumicino International Airport, train

    1. Take the train from Luzern to Zürich HBtrain train
    2. Fly from Zurich Airport (ZRH) to Fiumicino International Airport (FCO)plane plane ZRH - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    8h 16m
    €74–215

  7. Train, train to Milano Malpensa Airport, fly to Naples Airport

    1. Take the train from Luzern to Luganotrain train
    2. Take the train from Lugano to Malpensa Aeroporto T1train train
    3. Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane plane MXP - NAP
    4. Take the train from Napoli Centrale to Iserniatrain train
    9h 47m
    €83–249

  8. Train, train to Milan Linate Airport, fly to Naples Airport

    1. Take the train from Luzern to Luganotrain train
    2. Take the train from Lugano to Monzatrain train
    3. Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane plane LIN - NAP
    4. Take the train from Napoli Centrale to Iserniatrain train
    10h 4m
    €100–272

  9. Train, bus to Il Caravaggio International Airport, fly to Naples Airport

    1. Take the train from Luzern to Luganotrain train
    2. Take the train from Lugano to Milano Centraletrain train
    3. Take the bus from Piazza Luigi di Savoia to Bergamo Airport Bus Stationbus bus
    4. Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane plane BGY - NAP
    5. Take the train from Napoli Centrale to Iserniatrain train
    10h 27m
    €115–343

  10. Train, train to Milano Malpensa Airport, fly to Abruzzo Airport, bus

    1. Take the train from Luzern to Luganotrain train
    2. Take the train from Lugano to Malpensa Aeroporto T1train train
    3. Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane plane MXP - PSR
    4. Take the bus from Pescara to Iserniabus bus
    11h 4m
    €84–288

  11. Train, train to Milan Linate Airport, fly to Foggia Gino Lisa Airport, bus

    1. Take the train from Luzern to Luganotrain train
    2. Take the train from Lugano to Monzatrain train
    3. Fly from Milan Linate Airport (LIN) to Foggia Gino Lisa Airport (FOG)plane plane LIN - FOG
    4. Take the bus from Foggia to Iserniabus bus
    10h 29m
    €250–521

Luthern to Isernia by train

Calendar35Weekly Trains
Duration10h 8mAverage Duration
Ticket€118Cheapest Price
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Questions & Answers

What companies run services between Luthern, Switzerland and Isernia, Italy?

You can take a train from Luzern to Isernia via Lugano, Milano Centrale, and Roma Termini in around 10h 8m. Alternatively, you can take a bus from Luthern to Isernia via Campobasso and Campobasso Terminal Autobus in around 15h.

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