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How to get fromLugano to Iserniaby train (Trenitalia), bus, car, train or plane

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There are 11 ways to get from Lugano to Isernia by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lugano to Milano Centraletrain train
    2. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    3. Take the train from Roma Termini to Iserniatrain train Re
    7h 44m
    €90–222
  2. Bus via Bologna

    cheapest
    1. Take the bus from Lugano to Bologna Centralebus bus 421 / ...
    2. Take the bus from Bologna Centrale to Iserniabus bus 433
    14h 29m
    €33–105
  3. Bus

    1. Take the bus from Lugano to Caianellobus bus
    2. Take the bus from Casello - A1 Ingresso Caianello to Iserniabus bus 6
    12h 58m
    €66–91
  4. Drive 800.6 km

    1. Drive from Lugano to Iserniacar car 800.6 km
    7h 38m
    €136–197
  5. Train to Milano Malpensa Airport, fly to Naples Airport, train

    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane plane MXP - NAP
    3. Take the train from Napoli Centrale to Iserniatrain train
    7h 25m
    €41–156
  6. Train to Milan Linate Airport, fly to Naples Airport, train

    1. Take the train from Lugano to Seregnotrain train
    2. Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane plane LIN - NAP
    3. Take the train from Napoli Centrale to Iserniatrain train
    7h 47m
    €58–171
  7. Train to Milano Malpensa Airport, fly to Fiumicino International Airport, train

    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Fiumicino International Airport (FCO)plane plane MXP - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    7h 40m
    €72–210
  8. Train, bus to Il Caravaggio International Airport, fly to Naples Airport

    1. Take the train from Lugano to Milano Centraletrain train
    2. Take the bus from Piazza Luigi di Savoia to Bergamo Airport Bus Stationbus bus
    3. Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane plane BGY - NAP
    4. Take the train from Napoli Centrale to Iserniatrain train
    8h 3m
    €85–243
  9. Train to Milan Linate Airport, fly to Fiumicino International Airport, train

    1. Take the train from Lugano to Seregnotrain train
    2. Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane plane LIN - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    8h 2m
    €75–225
  10. Train to Milano Malpensa Airport, fly to Abruzzo Airport, bus

    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane plane MXP - PSR
    3. Take the bus from Pescara to Iserniabus bus
    8h 42m
    €38–176
  11. Train to Milan Linate Airport, fly to Foggia Gino Lisa Airport, bus

    1. Take the train from Lugano to Seregnotrain train
    2. Fly from Milan Linate Airport (LIN) to Foggia Gino Lisa Airport (FOG)plane plane LIN - FOG
    3. Take the bus from Foggia to Iserniabus bus
    8h 12m
    €103–338

Lugano to Isernia by train

Calendar35Weekly Trains
Duration7h 44mAverage Duration
Ticket€90Cheapest Price
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Questions & Answers

What companies run services between Lugano, Switzerland and Isernia, Italy?

You can take a train from Lugano to Isernia via Milano Centrale and Roma Termini in around 7h 44m. Alternatively, you can take a bus from Lugano to Isernia via Caianello and Casello - A1 Ingresso Caianello in around 12h 58m.

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