There are 11 ways to get from Lugano to Isernia by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Iserniatrain Re
7h 44m€90–222Bus via Bologna
cheapest- Take the bus from Lugano to Bologna Centralebus 421 / ...
- Take the bus from Bologna Centrale to Iserniabus 433
14h 29m€33–105Bus
- Take the bus from Lugano to Caianellobus
- Take the bus from Casello - A1 Ingresso Caianello to Iserniabus 6
12h 58m€66–91Drive 800.6 km
- Drive from Lugano to Iserniacar 800.6 km
7h 38m€136–197Train to Milano Malpensa Airport, fly to Naples Airport, train
- Take the train from Lugano to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane MXP - NAP
- Take the train from Napoli Centrale to Iserniatrain
7h 25m€41–156Train to Milan Linate Airport, fly to Naples Airport, train
- Take the train from Lugano to Seregnotrain
- Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane LIN - NAP
- Take the train from Napoli Centrale to Iserniatrain
7h 47m€58–171Train to Milano Malpensa Airport, fly to Fiumicino International Airport, train
- Take the train from Lugano to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Fiumicino International Airport (FCO)plane MXP - FCO
- Take the train from Roma Termini to Iserniatrain
7h 40m€72–210Train, bus to Il Caravaggio International Airport, fly to Naples Airport
- Take the train from Lugano to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Bergamo Airport Bus Stationbus
- Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane BGY - NAP
- Take the train from Napoli Centrale to Iserniatrain
8h 3m€85–243Train to Milan Linate Airport, fly to Fiumicino International Airport, train
- Take the train from Lugano to Seregnotrain
- Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane LIN - FCO
- Take the train from Roma Termini to Iserniatrain
8h 2m€75–225Train to Milano Malpensa Airport, fly to Abruzzo Airport, bus
- Take the train from Lugano to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane MXP - PSR
- Take the bus from Pescara to Iserniabus
8h 42m€38–176Train to Milan Linate Airport, fly to Foggia Gino Lisa Airport, bus
- Take the train from Lugano to Seregnotrain
- Fly from Milan Linate Airport (LIN) to Foggia Gino Lisa Airport (FOG)plane LIN - FOG
- Take the bus from Foggia to Iserniabus
8h 12m€103–338
Lugano to Isernia by train
Questions & Answers
The cheapest way to get from Lugano to Isernia is to bus via Bologna which costs €30 - €110 and takes 14h 29m.
The fastest way to get from Lugano to Isernia is to train and fly which takes 7h 25m and costs €40 - €160.
No, there is no direct bus from Lugano to Isernia. However, there are services departing from Lugano and arriving at Isernia via Casello - A1 Ingresso Caianello. The journey, including transfers, takes approximately 12h 58m.
No, there is no direct train from Lugano to Isernia. However, there are services departing from Lugano and arriving at Isernia via Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 7h 44m.
The distance between Lugano and Isernia is 824 km. The road distance is 800.6 km.
The best way to get from Lugano to Isernia without a car is to train which takes 7h 44m and costs €90 - €230.
It takes approximately 7h 44m to get from Lugano to Isernia, including transfers.
Lugano to Isernia bus services, operated by FlixBus, depart from Lugano station.
Lugano to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Lugano station.
The best way to get from Lugano to Isernia is to train which takes 7h 44m and costs €90 - €230. Alternatively, you can bus, which costs €65 - €95 and takes 12h 58m.
What companies run services between Lugano, Switzerland and Isernia, Italy?
You can take a train from Lugano to Isernia via Milano Centrale and Roma Termini in around 7h 44m. Alternatively, you can take a bus from Lugano to Isernia via Caianello and Casello - A1 Ingresso Caianello in around 12h 58m.
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €40–120
Flights from Il Caravaggio International Airport to Naples Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €40–140
Flights from Il Caravaggio International Airport to Naples Airport via Cagliari
- Ave. Duration
- 3h 40m
- When
- Monday and Sunday
- Estimated price
- €40–140
Flights from Milano Malpensa Airport to Abruzzo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €23–140
- Website
- ita-airways.com
Flights from Milan Linate Airport to Naples Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €40–130
Flights from Milan Linate Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- €40–130
Flights from Milan Linate Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €45–150
- Website
- easyjet.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €23–130
- Website
- aeroitalia.com
Flights from Milano Malpensa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €45–200
Flights from Milan Linate Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €120–360
Flights from Milan Linate Airport to Foggia Gino Lisa Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €70–550
- Website
- flexflight.dk
Flights from Milano Malpensa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €45–200
Flights from Milan Linate Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €120–360
Flights from Milan Linate Airport to Foggia Gino Lisa Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €70–550
- Website
- neosair.it
Flights from Milano Malpensa Airport to Fiumicino International Airport
- Ave. Duration
- 1h 25m
- When
- Wednesday
- Estimated price
- €130–320
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- https://www.sbb.ch/en
Train from Lugano to Seregno
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €25–45
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €50–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €45–100
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €13–55
- Website
- https://www.trenitalia.com/en.html
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- €8–14
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Lugano to Malpensa Aeroporto T1
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Website
- https://www.trenord.it/en/
Train from Lugano to Seregno
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 0827 34 117
- info@gruppodimaio.it
- Website
- gruppodimaio.it
Bus from Lugano to Caianello
- Ave. Duration
- 10h 50m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- gruppodimaio.it
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Casello - A1 Ingresso Caianello to Isernia
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Lugano to Bologna Centrale
- Ave. Duration
- 5h 5m
- Frequency
- Twice daily
- Estimated price
- €19–28
- Website
- https://www.flixbus.co.uk
Bus from Bologna Centrale to Isernia
- Ave. Duration
- 8h 24m
- Frequency
- Once daily
- Estimated price
- €18–60
- Website
- https://www.flixbus.co.uk
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €13–27
- Website
- https://www.flixbus.co.uk
Bus from Foggia to Isernia
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- €8–27
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Lugano to Bologna Centrale
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- €15–45
- Website
- https://www.itabus.it/en/home
- info@flibco.com
- Website
- flibco.com
Bus from Piazza Luigi di Savoia to Bergamo Airport Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €8–10
- Website
- https://www.flibco.com/en
- Phone
- +39 02 3008 9000
- mail@autostradale.it
- Website
- autostradale.it
Bus from Piazza Luigi di Savoia to Bergamo Airport Bus Station
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €4–17
- Website
- https://autostradale.it/?lang=en-GB
- Standard Rate
- €13–17
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
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More Questions & Answers
Lugano to Isernia bus services, operated by FlixBus, arrive at Bologna Centrale station.
Lugano to Isernia train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Milano Centrale station.
Yes, the driving distance between Lugano to Isernia is 801 km. It takes approximately 7h 38m to drive from Lugano to Isernia.
Book your Lugano to Isernia train tickets online with Omio.
Book your Lugano to Isernia bus tickets online with Omio and FlixBus.
There are 433+ hotels available in Isernia.














































