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How to get fromLugano to Iserniaby train (Trenitalia), bus, car, train, or plane

Find Transport to Isernia

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There are 11 ways to get from Lugano to Isernia by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Lugano to Milano Centraletrain train
    2. Take the train from Milano Centrale to Roma Terminitrain train
    3. Take the train from Roma Termini to Iserniatrain train Re
    7h 47m
    €112–184

  2. Train to Milano Malpensa Airport, fly to Naples Airport, train

    cheapest
    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane plane MXP - NAP
    3. Take the train from Caserta to Iserniatrain train
    7h 48m
    €35–176

  3. Bus

    1. Take the bus from Lugano to Caianellobus bus
    2. Take the bus from Casello - A1 Ingresso Caianello to Iserniabus bus 6
    12h 58m
    €66–91

  4. Drive  800.9 km

    1. Drive from Lugano to Iserniacar car 800.9 km
    7h 38m
    €169–243

  5. Bus via Bologna

    1. Take the bus from Lugano to Bolognabus bus FlixBus 421 / ...
    2. Take the bus from Bologna Centrale to Iserniabus bus 433
    14h 29m
    €71–108

  6. Train to Milan Linate Airport, fly to Fiumicino International Airport, train

    1. Take the train from Lugano to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane plane LIN - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    7h 55m
    €87–232

  7. Train to Milan Linate Airport, fly to Naples Airport, train

    1. Take the train from Lugano to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane plane LIN - NAP
    3. Take the train from Caserta to Iserniatrain train
    7h 58m
    €74–210

  8. Train to Milano Malpensa Airport, fly to Abruzzo Airport, bus

    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane plane MXP - PSR
    3. Take the bus from Pescara Airport to San Salvo Marinabus bus
    4. Take the bus from San Salvo Marina to Iserniabus bus
    8h 30m
    €35–178

  9. Train to Milan Linate Airport, fly to Foggia Gino Lisa Airport, bus

    1. Take the train from Lugano to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Foggia Gino Lisa Airport (FOG)plane plane LIN - FOG
    3. Take the bus from Foggia to Iserniabus bus
    8h 16m
    €95–294

  10. Train to Milano Malpensa Airport, fly to Salerno Costa D'Amalfi Airport, train

    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Salerno Costa D'Amalfi Airport (QSR)plane plane MXP - QSR
    3. Take the train from Salerno to Casertatrain train
    4. Take the train from Caserta to Iserniatrain train
    9h 58m
    €53–212

  11. Train to Milan Linate Airport, fly to Salerno Costa D'Amalfi Airport, train

    1. Take the train from Lugano to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Salerno Costa D'Amalfi Airport (QSR)plane plane LIN - QSR
    3. Take the train from Salerno to Casertatrain train
    4. Take the train from Caserta to Iserniatrain train
    10h 13m
    €84–316

Lugano to Isernia by bus and foot

Calendar2Weekly Services
Duration12h 58mAverage Duration
Ticket€66Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lugano to Isernia.ExpandLaunch map view
  • Distance: 842.7 km
  • Duration: 7h 47m

What companies run services between Lugano, Switzerland and Isernia, Italy?

You can take a train from Lugano to Isernia via Milano Centrale and Roma Termini in around 7h 47m. Alternatively, you can take a bus from Lugano to Isernia via Caianello and Casello - A1 Ingresso Caianello in around 12h 58m.

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