There are 6 ways to get from Lower Rio Grande Valley to Florida Keys by plane, bus (Greyhound, Flixbus), car, taxi, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Mcallen Miller International Airport to Key West International Airport
best- Fly from Mcallen Miller International Airport (MFE) to Key West International Airport (EYW)MFE - EYW
7h 48m$205–753Bus
- Take the bus from McAllen Central Station to Houston Bus Station
- Take the bus from Houston - Harrisburg Blvd to Miami
- Take the bus from Miami Airport Station to Big Pine Key
38h 19m$282–415Drive 1,652.7 mi
- Drive from Lower Rio Grande Valley to Florida Keys1,652.7 mi
29h 8m$302–436Taxi to Rio Grande Valley International Airport, fly to Key West International Airport
- Take the taxi from Lower Rio Grande Valley to Rio Grande Valley International Airport (HRL)
- Fly from Rio Grande Valley International Airport (HRL) to Key West International Airport (EYW)HRL - EYW
8h 57m$250–729Fly Mcallen Miller International Airport to Miami International Airport, shuttle
- Fly from Mcallen Miller International Airport (MFE) to Miami International Airport (MIA)MFE - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 34m$270–768Fly Mcallen Miller International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Mcallen Miller International Airport (MFE) to Fort Lauderdale–Hollywood International Airport (FLL)MFE - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
11h 6m$265–648
Mcallen Miller International Airport (MFE) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Lower Rio Grande Valley to Florida Keys is to bus which costs $280 - $420 and takes 38h 19m.
The fastest way to get from Lower Rio Grande Valley to Florida Keys is to fly which takes 7h 48m and costs $200 - $800.
The distance between Lower Rio Grande Valley and Florida Keys is 1072 miles. The road distance is 1662.4 miles.
The best way to get from Lower Rio Grande Valley to Florida Keys without a car is to bus which takes 38h 19m and costs $280 - $420.
It takes approximately 7h 48m to get from Lower Rio Grande Valley to Florida Keys, including transfers.
The best way to get from Lower Rio Grande Valley to Florida Keys is to fly which takes 7h 48m and costs $200 - $800. Alternatively, you can bus, which costs $280 - $420 and takes 38h 19m.
Yes, the driving distance between Lower Rio Grande Valley to Florida Keys is 1662 miles. It takes approximately 29h 8m to drive from Lower Rio Grande Valley to Florida Keys.
There are 376+ hotels available in Florida Keys.
What companies run services between Lower Rio Grande Valley, TX, USA and Florida Keys, FL, USA?
Allegiant Air, United Airlines, and American Airlines fly from Mcallen Miller International Airport (MFE) to Key West International Airport (EYW) twice daily. Alternatively, you can take a vehicle from Lower Rio Grande Valley to Florida Keys via McAllen Central Station, Houston Bus Station, Houston - Harrisburg Blvd, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 38h 19m.
- Website
- aa.com
Flights from Mcallen Miller International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $150–700
Flights from Rio Grande Valley International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 9h 33m
- When
- Every day
- Estimated price
- $130–600
Flights from Mcallen Miller International Airport to Miami International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $130–600
Flights from Mcallen Miller International Airport to Fort Lauderdale–Hollywood International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $100–460
- Website
- united.com
Flights from Mcallen Miller International Airport to Key West International Airport via Houston
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $130–650
Flights from Rio Grande Valley International Airport to Key West International Airport via Houston
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $110–550
Flights from Mcallen Miller International Airport to Miami International Airport via Houston
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $110–550
Flights from Mcallen Miller International Airport to Fort Lauderdale–Hollywood International Airport via Houston
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $85–410
- Website
- allegiantair.com
Flights from Mcallen Miller International Airport to Key West International Airport via Orlando Sanford
- Ave. Duration
- 4h 42m
- When
- Sunday
- Estimated price
- $140–650
- Website
- delta.com
Flights from Mcallen Miller International Airport to Miami International Airport via Austin
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $120–550
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from McAllen Central Station to Houston Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from McAllen Central Station to Houston Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Once daily
- Estimated price
- $40–95
- Schedules at
- flixbus.com
- Adult
- $40–95
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Houston - Harrisburg Blvd to Miami
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $180–230
- Schedules at
- omnibusexpress.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
- Ave. Duration
- 37 min
- Estimated price
- $90–110
Taxi service
- Phone
- +52 899 223 4178
- Website
- facebook.com
Multi Taxis Seguros
- Phone
- +52 899 902 0307
- Website
- multitaxisseguros.com.mx
City Taxi
- Phone
- +52 899 143 5516
- Website
- citytaxireynosa.com
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