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How to get fromLowell to San Diegoby plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, train or bus

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There are 6 ways to get from Lowell to San Diego by plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Boston Logan Airport

    best
    1. Fly from Boston Logan Airport (BOS) to San Diego International Airport (SAN)planeBOS - SAN
    8h 24m
    $182–507

  2. Train

    1. Take the train from Lowell to North Stationtrain
    2. Take the train from Boston to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
    4. Take the train from Fullerton Amtrak Station to San Diegotrain
    2d 23h
    $330–1,187

  3. Bus

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus
    2. Take the bus from Boston to Newark Penn Stationbus
    3. Take the bus from Newark Penn Station to St Louis Bus Stationbus
    4. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
    5. Take the bus from Los Angeles to San Diegobus
    3d 1h

  4. Drive 2,950 mi

    1. Drive from Lowell to San Diegocar2,950 mi
    2d 1h
    $539–778

  5. Train, bus to Manchester Airport, fly

    1. Take the train from Lowell to North Stationtrain
    2. Take the bus from Boston to Boston Manchester Airportbus
    3. Fly from Manchester Airport (MHT) to San Diego International Airport (SAN)planeMHT - SAN
    12h 16m
    $290–1,139

  6. Train, train to Theodore Francis Green State Airport, fly

    1. Take the train from Lowell to North Stationtrain
    2. Take the train from Boston to Providencetrain
    3. Fly from Theodore Francis Green State Airport (PVD) to San Diego International Airport (SAN)planePVD - SAN
    11h 51m
    $374–1,215

Lowell to San Diego by train and subway

Calendar7Weekly Services
Duration2d 23hAverage Duration
Ticket$330Cheapest Price
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Questions & Answers

What companies run services between Lowell, MA, USA and San Diego, CA, USA?

Alaska Airlines, Inc., JetBlue Airways, and four other airlines fly from Boston Logan Airport (BOS) to San Diego International Airport (SAN) every 3 hours. Alternatively, you can take a train from Lowell to San Diego via North Station, North Station, Back Bay, Boston, Chicago Union Station, and Fullerton Amtrak Station in around 2d 23h.

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