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How to get fromLowell to Pittsburghby train, plane, bus, bus (Greyhound), train (Amtrak), or car

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There are 7 ways to get from Lowell to Pittsburgh by train, plane, bus, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Boston Logan Airport, fly, bus

    best
    1. Take the train from Lowell to Anderson/Woburntrain train
    2. Fly from Boston Logan Airport (BOS) to Pittsburgh International Airport (PIT)plane plane BOS - PIT
    3. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    5h 32m

  2. Bus via Boston

    cheapest
    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from South Station to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Pittsburgh Greyhoundbus bus
    14h 35m
    $84–148

  3. Train

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Stationtrain train
    15h 49m
    $198–1,043

  4. Drive 570 mi

    1. Drive from Lowell to Pittsburghcar car 570 mi
    10h 23m
    $104–151

  5. Train, train to Theodore Francis Green State Airport, fly

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Ruggles to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Pittsburgh International Airport (PIT)plane plane PVD - PIT
    7h 42m
    $147–518

  6. Train, bus to Manchester Airport, fly

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Pittsburgh International Airport (PIT)plane plane MHT - PIT
    9h 20m
    $395–1,627

  7. Bus (Greyhound)

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminalbus bus Greyhound US0256S
    2. Take the bus from Port Authority Bus Terminal to Pittsburgh Intermodal Stationbus bus Greyhound US0410 / ...
    16h 39m
    $99–191

Lowell to Pittsburgh by bus

Calendar5Weekly Buses
Duration14h 35mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Lowell to Pittsburgh.ExpandLaunch map view
  • Distance: 548.9 mi
  • Duration: 5h 32m

What companies run services between Lowell, MA, USA and Pittsburgh, PA, USA?

You can take a bus from Robert B Kennedy Bus Transfer Center to Pittsburgh Greyhound via Boston, South Station, and Port Authority Bus Terminal in around 14h 35m. Alternatively, you can take a train from Lowell to Pittsburgh Amtrak Station via North Station, North Station, Back Bay, Boston, and Ny Moynihan Train Hall At Penn Station in around 15h 49m.

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