There are 10 ways to get from Lowell to Indiana by plane, bus (Greyhound, Flixbus), train, bus, car, bus (Greyhound), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Boston Logan Airport to Indianapolis
best- Fly from Boston Logan Airport (BOS) to Indianapolis (IND)plane BOS - IND
6h 9m$303–969Fly Boston Logan Airport to Chicago O'Hare International Airport, train
cheapest- Fly from Boston Logan Airport (BOS) to Chicago O'Hare International Airport (ORD)plane BOS - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
7h 9m$91–412Bus via Boston
- Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus
- Take the bus from Boston to New York Midtownbus
- Take the bus from New York Midtown to Indianapolisbus
23h 12m$155–247Train, bus
- Take the train from Lowell to North Stationtrain
- Take the train from Boston to Toledotrain
- Take the bus from Toledo to Indianapolisbus
24h 17m$459–778Drive 910.9 mi
- Drive from Lowell to Indianapoliscar 910.9 mi
16h 29m$151–218Fly Boston Logan Airport to Chicago Midway International Airport, train
- Fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW)plane BOS - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
6h 50m$121–582Train, bus to Manchester Airport, fly to Chicago Midway International Airport
- Take the train from Lowell to North Stationtrain
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Chicago Midway International Airport (MDW)plane MHT - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
8h 32m$112–502Train, train to Theodore Francis Green State Airport, fly to Chicago Midway International Airport
- Take the train from Lowell to North Stationtrain
- Take the train from Ruggles to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Chicago Midway International Airport (MDW)plane PVD - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
8h 58m$127–593Bus (Greyhound)
- Take the bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminalbus Greyhound US0256S
- Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus Greyhound US0421
26h 4m$187–289Train
- Take the train from Lowell to North Stationtrain
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain
29h 51m$558–1,563
Lowell to Indiana by bus
Comparing Your Travel Options
The cheapest way to get from Lowell to Indiana is to drive which costs $150 - $220 and takes 16h 29m.
The fastest way to get from Lowell to Indiana is to fly which takes 6h 9m and costs $300 - $1,000.
No, there is no direct bus from Lowell to Indiana. However, there are services departing from Robert B Kennedy Bus Transfer Center and arriving at Indianapolis via Boston and New York Midtown. The journey, including transfers, takes approximately 23h 12m.
No, there is no direct train from Lowell to Indiana. However, there are services departing from Lowell and arriving at Indianapolis via North Station, Boston and Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 29h 51m.
The distance between Lowell and Indiana is 862 miles. The road distance is 916.2 miles.
The best way to get from Lowell to Indiana without a car is to bus via Boston which takes 23h 12m and costs $150 - $250.
It takes approximately 6h 9m to get from Lowell to Indiana, including transfers.
Lowell to Indiana bus services, operated by Greyhound USA, depart from Robert B Kennedy Bus Transfer Center station.
Lowell to Indiana train services, operated by MBTA, depart from Lowell station.
The best way to get from Lowell to Indiana is to fly which takes 6h 9m and costs $300 - $1,000. Alternatively, you can bus via Boston, which costs $150 - $250 and takes 23h 12m, you could also train, which costs $550 - $1,600 and takes 29h 51m.
What companies run services between Lowell, MA, USA and Indiana, USA?
American Airlines, Delta, and two other airlines fly from Boston Logan Airport (BOS) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Robert B Kennedy Bus Transfer Center to Indianapolis via Boston and New York Midtown in around 23h 12m.
- Website
- southwest.com
Flights from Boston Logan Airport to Indianapolis via Baltimore
- Ave. Duration
- 4h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Flights from Boston Logan Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h 50m
- When
- Monday and Thursday
- Estimated price
- $150–750
Flights from Boston Logan Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- $100–550
Flights from Manchester Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 37m
- When
- Every day
- Estimated price
- $85–460
Flights from Manchester Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $95–490
Flights from Manchester Airport to Chicago Midway International Airport via Nashville
- Ave. Duration
- 6h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Theodore Francis Green State Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $100–550
Flights from Theodore Francis Green State Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Boston Logan Airport to Indianapolis
- Ave. Duration
- 2h 51m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to Indianapolis via New York JFK
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- $70–380
- Website
- united.com
Flights from Boston Logan Airport to Indianapolis via Newark
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to Indianapolis via Washington Dulles
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $140–750
Flights from Boston Logan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- $70–380
- Website
- delta.com
Flights from Boston Logan Airport to Indianapolis
- Ave. Duration
- 2h 49m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to Indianapolis via Detroit
- Ave. Duration
- 4h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Boston Logan Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $100–550
Flights from Boston Logan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 3h 1m
- When
- Every day
- Estimated price
- $70–380
Flights from Theodore Francis Green State Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $100–550
- Website
- jetblue.com
Flights from Boston Logan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- $70–380
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Ruggles to TF Green Airport
- Ave. Duration
- 1h 22m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–15
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Toledo
- Ave. Duration
- 17h 16m
- Frequency
- Once daily
- Estimated price
- $430–700
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 57m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Indianapolis
- Ave. Duration
- 23h 15m
- Frequency
- 3 times a week
- Estimated price
- $500–800
- Website
- Amtrak
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 44m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Robert B Kennedy Bus Transfer Center to Boston
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $5–8
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminal
- Ave. Duration
- 7h 59m
- Frequency
- 5 times a week
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Indianapolis Union Station
- Ave. Duration
- 17h 5m
- Frequency
- 3 times a day
- Estimated price
- $140–220
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to New York Midtown
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from New York Midtown to Indianapolis
- Ave. Duration
- 16h 15m
- Frequency
- Once daily
- Estimated price
- $120–190
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Toledo to Indianapolis
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
Want to know more about travelling around United States
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Booking & Getting There
Lowell to Indiana bus services, operated by Greyhound USA, arrive at Boston station.
Lowell to Indiana train services, operated by MBTA, arrive at North Station.
Yes, the driving distance between Lowell to Indiana is 916 miles. It takes approximately 16h 29m to drive from Lowell to Indiana.
Book your Lowell to Indiana bus tickets online with Omio and FlixBus.
There are 913+ hotels available in Indiana.





















