There are 11 ways to get from Lowell to Frederick by plane, bus, train, bus (Greyhound, Flixbus), car, subway, train (Amtrak), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Boston Logan Airport to Baltimore-Washington International Airport, bus
best- Fly from Boston Logan Airport (BOS) to Baltimore-Washington International Airport (BWI)plane BOS - BWI
- Take the bus from Baltimore to Frederickbus
6h 4m$231–1,077Drive 442.3 mi
cheapest- Drive from Lowell to Frederickcar 442.3 mi
8h 20m$79–113Train, bus
- Take the train from Lowell to North Stationtrain
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshalltrain
- Take the bus from BWI Amtrak Station to Frederick Transit Centerbus Bwi
11h 10mBus via Boston
- Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus
- Take the bus from Boston to New York Midtownbus
- Take the bus from New York Midtown to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore to Frederickbus
11h 18m$135–228Train to Boston Logan Airport, fly to Ronald Reagan Washington National Airport, subway, bus
- Take the train from Lowell to Anderson/Woburntrain
- Fly from Boston Logan Airport (BOS) to Ronald Reagan Washington National Airport (DCA)plane BOS - DCA
- Take the subway from Gallery Place, Red Line Track 2 Platform to Shady Grove, Red Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
6h 42m$487–1,326Fly Boston Logan Airport to Washington Dulles International Airport, subway, bus
- Fly from Boston Logan Airport (BOS) to Washington Dulles International Airport (IAD)plane BOS - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
7h 16m$867–1,125Train, bus to Manchester Airport, fly to Baltimore-Washington International Airport, bus
- Take the train from Lowell to North Stationtrain
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Baltimore-Washington International Airport (BWI)plane MHT - BWI
- Take the bus from Baltimore to Frederickbus
7h 58m$147–517Train, bus to Manchester Airport, fly to Ronald Reagan Washington National Airport, bus
- Take the train from Lowell to North Stationtrain
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Ronald Reagan Washington National Airport (DCA)plane MHT - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
8h 40m$108–586Fly Boston Logan Airport to Philadelphia International Airport, train, bus
- Fly from Boston Logan Airport (BOS) to Philadelphia International Airport (PHL)plane BOS - PHL
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Take the bus from BWI Amtrak Station to Frederick Transit Centerbus
8h 27mTrain
- Take the train from Lowell to North Stationtrain
- Take the train from Boston to Washington Union Stationtrain
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
11h 26m$260–415Bus
- Take the bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore Downtown Bus Station to Frederick Bus Stationbus
16h 4m$178–246
Lowell to Frederick by bus
Comparing Your Travel Options
The cheapest way to get from Lowell to Frederick is to drive which costs $75 - $120 and takes 8h 20m.
The fastest way to get from Lowell to Frederick is to fly and bus which takes 6h 4m and costs $230 - $1,100.
No, there is no direct bus from Lowell to Frederick. However, there are services departing from Robert B Kennedy Bus Transfer Center and arriving at Frederick via Boston, New York Midtown and Baltimore. The journey, including transfers, takes approximately 11h 18m.
No, there is no direct train from Lowell to Frederick. However, there are services departing from Lowell and arriving at FREDERICK MARC wb via North Station, Boston and Washington Union Station. The journey, including transfers, takes approximately 11h 26m.
The distance between Lowell and Frederick is 450 miles. The road distance is 444.8 miles.
The best way to get from Lowell to Frederick without a car is to train and bus which takes 11h 10m and costs .
It takes approximately 6h 4m to get from Lowell to Frederick, including transfers.
Lowell to Frederick bus services, operated by Greyhound USA, depart from Robert B Kennedy Bus Transfer Center station.
Lowell to Frederick train services, operated by MBTA, depart from Lowell station.
The best way to get from Lowell to Frederick is to bus via Boston which takes 11h 18m and costs $130 - $230. Alternatively, you can train, which costs $260 - $420 and takes 11h 26m.
What companies run services between Lowell, MA, USA and Frederick, MD, USA?
You can take a bus from Robert B Kennedy Bus Transfer Center to Frederick via Boston, New York Midtown, and Baltimore in around 11h 18m. Alternatively, you can take a train from Lowell to FREDERICK MARC wb via North Station, North Station, Back Bay, Boston, and Washington Union Station in around 11h 26m.
- Website
- aa.com
Flights from Boston Logan Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $100–650
Flights from Manchester Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $85–550
Flights from Boston Logan Airport to Philadelphia International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $65–440
- Website
- delta.com
Flights from Boston Logan Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $70–440
Flights from Boston Logan Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $100–650
Flights from Boston Logan Airport to Washington Dulles International Airport via New York JFK
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $75–480
Flights from Boston Logan Airport to Philadelphia International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $65–440
- Website
- southwest.com
Flights from Boston Logan Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $70–440
Flights from Manchester Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $60–380
Flights from Boston Logan Airport to Philadelphia International Airport via Baltimore-Washington International Airport
- Ave. Duration
- 4h
- When
- Tuesday and Wednesday
- Estimated price
- $80–490
- Website
- jetblue.com
Flights from Boston Logan Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $100–650
Flights from Boston Logan Airport to Philadelphia International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $65–440
- Website
- united.com
Flights from Boston Logan Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $75–480
Flights from Boston Logan Airport to Washington Dulles International Airport via Newark
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $75–480
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Lowell to Anderson/Woburn
- Ave. Duration
- 19 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $2–8
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 57m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshall
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- $100–170
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from Boston to Washington Union Station
- Ave. Duration
- 8h 10m
- Frequency
- Every 4 hours
- Estimated price
- $250–390
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 44m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshall
- Ave. Duration
- 2h 32m
- Frequency
- 5 times a day
- Estimated price
- $45–700
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $45–480
- First Class
- $180–700
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from Boston to Washington Union Station
- Ave. Duration
- 6h 56m
- Frequency
- Every 4 hours
- Estimated price
- $100–900
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $100–550
- First Class
- $310–900
Subway from Gallery Place, Red Line Track 2 Platform to Shady Grove, Red Line Center Platform
- Ave. Duration
- 35 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
Subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platform
- Ave. Duration
- 49 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from Washington Union Station to FREDERICK MARC wb
- Ave. Duration
- 1h 41m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
- Phone
- +1 410-912-6000
- reservations@bayrunnershuttle.com
- Website
- BayRunner Shuttle
Bus from Baltimore to Frederick
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Schedules at
- BayRunner Shuttle
Bus from Baltimore to Frederick
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $65–110
- Schedules at
- BayRunner Shuttle
Bus from Baltimore to Frederick
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Schedules at
- BayRunner Shuttle
Bus from Baltimore Downtown Bus Station to Frederick Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $90–110
- Schedules at
- BayRunner Shuttle
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from BWI Amtrak Station to Frederick Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Website
- Amtrak
Bus from BWI Amtrak Station to Frederick Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Robert B Kennedy Bus Transfer Center to Boston
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $5–8
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminal
- Ave. Duration
- 7h 59m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Baltimore Downtown Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Frederick Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a day
- Estimated price
- $15–23
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to New York Midtown
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from New York Midtown to Baltimore Downtown Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Hourly
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
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Booking & Getting There
Lowell to Frederick bus services, operated by Greyhound USA, arrive at Boston station.
Lowell to Frederick train services, operated by MBTA, arrive at North Station.
Yes, the driving distance between Lowell to Frederick is 445 miles. It takes approximately 8h 20m to drive from Lowell to Frederick.
Book your Lowell to Frederick bus tickets online with Omio.
There are four+ hotels available in Frederick.























