Rome2Rio

How to get fromLowell to Chicagoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Find Transport to Chicago

See all options

There are 9 ways to get from Lowell to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Chicago Midway International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW)plane plane BOS - MDW
    5h 31m
    $103–492

  2. Train, bus to Manchester Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Chicago O'Hare International Airport (ORD)plane plane MHT - ORD
    7h 50m
    $78–362

  3. Train

    1. Take the train from Lowell to North Stationtrain train Lowell Line
    2. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    24h 12m
    $558–913

  4. Bus

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Chicago Bus Stationbus bus
    27h 45m
    $185–297

  5. Drive  961.5 mi

    1. Drive from Lowell to Chicagocar car 961.5 mi
    17h 35m
    $176–254

  6. Fly Boston Logan Airport to Chicago O'Hare International Airport

    1. Fly from Boston Logan Airport (BOS) to Chicago O'Hare International Airport (ORD)plane plane BOS - ORD
    5h 53m
    $613–1,022

  7. Train, bus to Manchester Airport, fly to Chicago Midway International Airport

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Chicago Midway International Airport (MDW)plane plane MHT - MDW
    7h 15m
    $98–452

  8. Train, train to Theodore Francis Green State Airport, fly to Chicago Midway International Airport

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Ruggles to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Chicago Midway International Airport (MDW)plane plane PVD - MDW
    7h 46m
    $114–533

  9. Fly Boston Logan Airport to General Mitchell International Airport, train

    1. Fly from Boston Logan Airport (BOS) to General Mitchell International Airport (MKE)plane plane BOS - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    7h 56m
    $708–2,006

Lowell to Chicago by train and subway

Calendar7Weekly Services
Duration24h 12mAverage Duration
Ticket$558Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Lowell to Chicago.ExpandLaunch map view
  • Distance: 896.3 mi
  • Duration: 5h 31m

What companies run services between Lowell, MA, USA and Chicago, IL, USA?

Southwest Airlines and Delta fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, you can take a train from Lowell to Chicago Union Station via North Station, North Station, Back Bay, and Boston in around 24h 12m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There