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How to get fromLowell to Chicagoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, train or bus

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There are 9 ways to get from Lowell to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Chicago Midway International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW)planeBOS - MDW
    5h 41m
    $99–462

  2. Train, train to Theodore Francis Green State Airport, fly to Chicago Midway International Airport

    cheapest
    1. Take the train from Lowell to North Stationtrain
    2. Take the train from Boston to Providencetrain
    3. Fly from Theodore Francis Green State Airport (PVD) to Chicago Midway International Airport (MDW)planePVD - MDW
    6h 59m
    $91–1,010

  3. Train

    1. Take the train from Lowell to North StationtrainLowell Line
    2. Take the train from Boston to Chicago Union StationtrainLake Shore Limited
    24h 12m
    $147–763

  4. Bus

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus
    2. Take the bus from Boston to Newark Penn Stationbus
    3. Take the bus from Newark Penn Station to Chicago Bus Stationbus
    27h 15m
    $134–302

  5. Drive 962.2 mi

    1. Drive from Lowell to Chicagocar962.2 mi
    17h 25m
    $176–254

  6. Fly Boston Logan Airport to Chicago O'Hare International Airport

    1. Fly from Boston Logan Airport (BOS) to Chicago O'Hare International Airport (ORD)planeBOS - ORD
    6h 2m
    $114–332

  7. Train, bus to Manchester Airport, fly to Chicago Midway International Airport

    1. Take the train from Lowell to North Stationtrain
    2. Take the bus from Boston to Boston Manchester Airportbus
    3. Fly from Manchester Airport (MHT) to Chicago Midway International Airport (MDW)planeMHT - MDW
    7h 19m
    $122–597

  8. Train, bus to Manchester Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Lowell to North Stationtrain
    2. Take the bus from Boston to Boston Manchester Airportbus
    3. Fly from Manchester Airport (MHT) to Chicago O'Hare International Airport (ORD)planeMHT - ORD
    7h 45m
    $102–457

  9. Fly Boston Logan Airport to General Mitchell International Airport, train

    1. Fly from Boston Logan Airport (BOS) to General Mitchell International Airport (MKE)planeBOS - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain
    7h 47m
    $296–742

Lowell to Chicago by train and subway

Calendar7Weekly Services
Duration24h 12mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

What companies run services between Lowell, MA, USA and Chicago, IL, USA?

Southwest Airlines and Delta fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW) 4 times a day. Alternatively, you can take a train from Lowell to Chicago Union Station via North Station, North Station, Back Bay, and Boston in around 24h 12m.

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