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How to get fromLowell to Buffaloby train, plane, bus (Greyhound), train (Amtrak), car or bus

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There are 6 ways to get from Lowell to Buffalo by train, plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Lowell to Anderson/Woburntrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    4h 54m
    $146–945

  2. Train, bus

    cheapest
    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    14h 50m
    $79–200

  3. Bus (Greyhound)

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus Greyhound US0256S
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    11h 50m
    $80–159

  4. Train

    1. Take the train from Lowell to North Stationtrain train Lowell Line
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    14h 49m
    $147–378

  5. Drive 435 mi

    1. Drive from Lowell to Buffalocar car 435 mi
    8h 42m
    $80–115

  6. Fly to Rochester, bus

    1. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 16m
    $268–812

Lowell to Buffalo by bus (Greyhound)

Calendar5Weekly Buses
Duration11h 50mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

What companies run services between Lowell, MA, USA and Buffalo, NY, USA?

You can take a bus from Robert B Kennedy Bus Transfer Center to Buffalo via Boston in around 11h 50m. Alternatively, you can take a train from Lowell to Buffalo via North Station, North Station, Back Bay, Boston, and Buffalo Depew Station in around 14h 49m.

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