There are 7 ways to get from Louisville to Key West by car, plane, bus (Amtrak, Greyhound, Flixbus), bus, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Blue Grass Airport, fly
best- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Key West International Airport (EYW)plane LEX - EYW
5h 37m$124–582Bus
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
29h 51m$141–315Drive 1,175.1 mi
- Drive from Louisville to Key Westcar 1,175.1 mi
22h 4m$215–310Fly from Louisville International Airport
- Fly from Louisville International Airport (SDF) to Key West International Airport (EYW)plane SDF - EYW
6h 22m$143–716Bus to Evansville, fly
- Take the bus from Louisville, KY to Evansville, INbus
- Fly from Evansville (EVV) to Key West International Airport (EYW)plane EVV - EYW
8h 26m$200–789Bus to Covington, fly
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus
- Fly from Covington (CVG) to Key West International Airport (EYW)plane CVG - EYW
6h 37m$203–1,008Bus, shuttle
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Tallahasseebus
- Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to Miami Airportbus
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
30h 54m$311–542
Louisville to Key West by bus and foot
Questions & Answers
The cheapest way to get from Louisville to Key West is to bus which costs $140 - $320 and takes 29h 51m.
The fastest way to get from Louisville to Key West is to drive and fly which takes 5h 37m and costs $120 - $600.
No, there is no direct bus from Louisville to Key West. However, there are services departing from Louisville, KY and arriving at N Roosevelt & 3rd Street via Nashville Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 29h 51m.
The distance between Louisville and Key West is 1026 miles. The road distance is 1182 miles.
The best way to get from Louisville to Key West without a car is to bus which takes 29h 51m and costs $140 - $320.
It takes approximately 5h 37m to get from Louisville to Key West, including transfers.
Louisville to Key West bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
The best way to get from Louisville to Key West is to bus which takes 29h 51m and costs $140 - $320. Alternatively, you can fly, which costs $140 - $750 and takes 6h 22m.
Louisville to Key West bus services, operated by Amtrak Thruway, arrive at Nashville station.
Yes, the driving distance between Louisville to Key West is 1182 miles. It takes approximately 22h 4m to drive from Louisville to Key West.
What companies run services between Louisville, KY, USA and Key West, FL, USA?
You can take a bus from Louisville, KY to N Roosevelt & 3rd Street via Nashville Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 29h 51m. Alternatively, Delta, American Airlines, and two other airlines fly from Louisville International Airport (SDF) to Key West International Airport (EYW) 4 times a day.
- Website
- delta.com
Flights from Blue Grass Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $130–700
Flights from Evansville to Key West International Airport via Atlanta
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $130–700
Flights from Covington to Key West International Airport via Atlanta
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $180–950
- Website
- aa.com
Flights from Blue Grass Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $110–600
Flights from Blue Grass Airport to Key West International Airport via Miami
- Ave. Duration
- 6h 58m
- When
- Saturday
- Estimated price
- $110–600
Flights from Blue Grass Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 7h 11m
- When
- Sunday
- Estimated price
- $150–700
Flights from Louisville International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 51m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Evansville to Key West International Airport via Charlotte
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $150–750
Flights from Evansville to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 18m
- When
- Every day
- Estimated price
- $200–900
Flights from Evansville to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 7h 15m
- When
- Every day
- Estimated price
- $180–850
- Website
- allegiantair.com
Flights from Blue Grass Airport to Key West International Airport via St. Petersburg
- Ave. Duration
- 4h 12m
- When
- Thursday and Sunday
- Estimated price
- $100–550
Flights from Evansville to Key West International Airport via Orlando Sanford
- Ave. Duration
- 4h 49m
- When
- Thursday and Sunday
- Estimated price
- $140–700
Flights from Evansville to Key West International Airport via St. Petersburg
- Ave. Duration
- 5h 20m
- When
- Monday and Friday
- Estimated price
- $130–700
Flights from Covington to Key West International Airport
- Ave. Duration
- 2h 38m
- When
- Monday and Friday
- Estimated price
- $180–950
Flights from Covington to Key West International Airport via St. Petersburg
- Ave. Duration
- 4h 42m
- When
- Friday
- Estimated price
- $180–950
- Website
- united.com
Flights from Blue Grass Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $150–700
- Website
- flybreeze.com
Flights from Louisville International Airport to Key West International Airport via Orlando
- Ave. Duration
- 6h 26m
- When
- Monday and Friday
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $65–140
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–30
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to Tallahassee
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–60
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $55–170
- Schedules at
- flixbus.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Tallahassee - FSU - Old St Augustine at Intramural Field to Miami Airport
- Ave. Duration
- 9h 40m
- Frequency
- 5 times a day
- Estimated price
- $29–140
- Website
- https://www.redcoachusa.com
- Web
- $29–140
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
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