There are 7 ways to get from Louisville to Key Largo by plane, shuttle, bus (Amtrak, Greyhound, Flixbus), car, or bus (Amtrak, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Miami International Airport, shuttle
best- Fly from Louisville International Airport (SDF) to Miami International Airport (MIA)plane SDF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 17m$202–683Bus
cheapest- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
25h 15m$188–317Drive 1,076.3 mi
- Drive from Louisville to Key Largocar 1,076.3 mi
19h 50m$197–284Fly Louisville International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Louisville International Airport (SDF) to Fort Lauderdale–Hollywood International Airport (FLL)plane SDF - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 37m$232–753Drive to Covington, fly to Miami International Airport, shuttle
- Drive from Louisville to Covington (CVG)car
- Fly from Covington (CVG) to Miami International Airport (MIA)plane CVG - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 29m$287–755Drive to Covington, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Drive from Louisville to Covington (CVG)car
- Fly from Covington (CVG) to Fort Lauderdale–Hollywood International Airport (FLL)plane CVG - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 51m$327–825Bus via Tallahassee
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Tallahasseebus
- Take the bus from Tallahassee to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
29h 25m$228–342
Louisville to Key Largo by bus
Comparing Your Travel Options
The cheapest way to get from Louisville to Key Largo is to bus which costs $180 - $320 and takes 25h 15m.
The fastest way to get from Louisville to Key Largo is to fly and shuttle which takes 6h 17m and costs $200 - $700.
No, there is no direct bus from Louisville to Key Largo. However, there are services departing from Louisville, KY and arriving at Key Largo Bus Stop via Nashville Bus Station, Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 25h 15m.
The distance between Louisville and Key Largo is 983 miles. The road distance is 1082.6 miles.
The best way to get from Louisville to Key Largo without a car is to bus which takes 25h 15m and costs $180 - $320.
It takes approximately 6h 17m to get from Louisville to Key Largo, including transfers.
Louisville to Key Largo bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Key Largo bus services, operated by Amtrak Thruway, arrive at Nashville station.
Yes, the driving distance between Louisville to Key Largo is 1083 miles. It takes approximately 19h 50m to drive from Louisville to Key Largo.
Book your Louisville to Key Largo bus tickets online with Omio.
What companies run services between Louisville, KY, USA and Key Largo, FL, USA?
You can take a bus from Louisville, KY to Key Largo Bus Stop via Nashville Bus Station, Atlanta Bus Station, and Miami Airport Station in around 25h 15m.
- Website
- delta.com
Flights from Louisville International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $110–600
Flights from Covington to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 31m
- When
- Every day
- Estimated price
- $140–750
- Website
- southwest.com
Flights from Louisville International Airport to Miami International Airport via Orlando
- Ave. Duration
- 4h 20m
- When
- Monday to Friday
- Estimated price
- $100–550
Flights from Louisville International Airport to Miami International Airport via Nashville
- Ave. Duration
- 5h 7m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $100–550
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 30m
- When
- Saturday
- Estimated price
- $110–600
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 4h 10m
- When
- Tuesday to Friday
- Estimated price
- $110–600
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport via Nashville
- Ave. Duration
- 4h 22m
- When
- Saturday and Sunday
- Estimated price
- $110–600
- Website
- aa.com
Flights from Louisville International Airport to Miami International Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $120–600
Flights from Covington to Miami International Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- $130–650
- Website
- allegiantair.com
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 24m
- When
- Monday and Friday
- Estimated price
- $110–600
Flights from Covington to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 28m
- When
- Thursday, Sunday, Friday, and Monday
- Estimated price
- $140–750
- Website
- flyfrontier.com
Flights from Covington to Miami International Airport
- Ave. Duration
- 2h 36m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $170–600
Flights from Covington to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 35m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $190–650
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Nashville
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Bus from Louisville, KY to Nashville
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $120–190
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–16
- Website
- Greyhound
Bus from Nashville Bus Station to Tallahassee
- Ave. Duration
- 9h 10m
- Frequency
- Once daily
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Tallahassee to Miami Airport Station
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- $100–150
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–16
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
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Booking & Getting There
There are 314+ hotels available in Key Largo.





