There are 2 ways to get from Louisville to Indianapolis by bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  2 h 10 min

  1. Take the bus from Louisville, KY to Indianapolis, IN - Amtrak 8251 / ...

$12 - $40

1 alternative option

Drive  •  1 h 55 min

  1. Drive from Louisville to Indianapolis 115.5 miles

$11 - $17

Questions & Answers

The cheapest way to get from Louisville to Indianapolis is to drive which costs $11 - $17 and takes 1 h 55 min.

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The quickest way to get from Louisville to Indianapolis is to drive which costs $11 - $17 and takes 1 h 55 min.

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The distance between Louisville and Indianapolis is 107 miles. The road distance is 115.5 miles.

Get driving directions

The bus from Louisville, KY to Indianapolis, IN - Amtrak takes 2 h 10 min including transfers and departs five times a day.

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Yes, there is a direct bus departing from Louisville, KY and arriving at Indianapolis, IN - Amtrak. Services depart five times a day, and operate every day. The journey takes approximately 2 h 10 min.

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What companies run services between Louisville, KY, USA and Indianapolis, IN, USA?

Amtrak operates a bus from Louisville to Indianapolis twice daily, and the journey takes 2 h 10 min. Two other operators also service this route.

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