There are 7 ways to get from Louisville to Independence by bus, train, car, plane, or bus (Amtrak, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Louisville, KY to Evansville, INbus
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Independence Stationtrain
13h$101–146Bus
cheapest- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus Greyhound US0421D
15h 23m$83–184Drive 497.6 mi
- Drive from Louisville to Independencecar 497.6 mi
8h 22m$91–132Fly from Louisville International Airport
- Fly from Louisville International Airport (SDF) to Kansas City (MCI)plane SDF - MCI
8h 22m$112–703Bus to Indianapolis, fly
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Fly from Indianapolis (IND) to Kansas City (MCI)plane IND - MCI
9h 29m$253–612Bus to Nashville, fly
- Take the bus from Louisville, KY to Nashvillebus
- Fly from Nashville (BNA) to Kansas City (MCI)plane BNA - MCI
9h 47m$185–498Bus to Covington, fly
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus
- Fly from Covington (CVG) to Kansas City (MCI)plane CVG - MCI
11h 21m$162–895
Louisville to Independence by bus and train
Questions & Answers
The cheapest way to get from Louisville to Independence is to drive which costs $90 - $140 and takes 8h 22m.
The fastest way to get from Louisville to Independence is to fly which takes 8h 22m and costs $110 - $750.
No, there is no direct bus from Louisville to Independence. However, there are services departing from Louisville, KY and arriving at On White Oak At Osage Eb via Indianapolis Union Station and East Village - Bay A. The journey, including transfers, takes approximately 15h 23m.
The distance between Louisville and Independence is 559 miles. The road distance is 500.5 miles.
The best way to get from Louisville to Independence without a car is to bus and train which takes 13h and costs $100 - $150.
It takes approximately 13h to get from Louisville to Independence, including transfers.
Louisville to Independence bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
The best way to get from Louisville to Independence is to fly which takes 8h 22m and costs $110 - $750. Alternatively, you can bus, which costs $80 - $190 and takes 15h 23m.
Louisville to Independence bus services, operated by Amtrak Thruway, arrive at Indianapolis Union Station.
Independence is 1h behind Louisville. It is currently 10:56 PM in Louisville and 9:56 PM in Independence.
What companies run services between Louisville, KY, USA and Independence, MO, USA?
Southwest Airlines flies from Louisville International Airport (SDF) to Kansas City (MCI) once daily. Alternatively, you can take a bus from Louisville, KY to On White Oak At Osage Eb via Indianapolis Union Station, Kansas City Bus Station, and East Village - Bay A in around 15h 23m.
- Website
- southwest.com
Flights from Louisville International Airport to Kansas City via Nashville
- Ave. Duration
- 4h 25m
- When
- Monday to Wednesday
- Estimated price
- $110–700
Flights from Louisville International Airport to Kansas City via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–700
Flights from Indianapolis to Kansas City
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $85–550
Flights from Indianapolis to Kansas City via Chicago Midway
- Ave. Duration
- 3h 38m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–600
Flights from Nashville to Kansas City
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $85–550
Flights from Nashville to Kansas City via St. Louis
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $85–550
Flights from Nashville to Kansas City via Chicago Midway
- Ave. Duration
- 4h 16m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $110–600
Flights from Nashville to Kansas City via Indianapolis
- Ave. Duration
- 4h 15m
- When
- Saturday
- Estimated price
- $100–600
Flights from Covington to Kansas City via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday
- Estimated price
- $160–900
Flights from Covington to Kansas City via Chicago Midway
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–850
- Website
- delta.com
Flights from Nashville to Kansas City via Atlanta
- Ave. Duration
- 4h 14m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–650
Flights from Covington to Kansas City via Detroit
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $180–950
Flights from Covington to Kansas City via Atlanta
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Covington to Kansas City via Minneapolis
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $190–1,000
- Website
- aa.com
Flights from Indianapolis to Kansas City via Chicago O'Hare
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $95–600
Flights from Covington to Kansas City via Chicago O'Hare
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $150–850
- Website
- united.com
Flights from Indianapolis to Kansas City via Chicago O'Hare
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $95–600
Flights from Covington to Kansas City via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $150–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Independence Station
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $28–35
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Kansas City Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- Twice a week
- Estimated price
- $60–140
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
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More Questions & Answers
Yes, the driving distance between Louisville to Independence is 501 miles. It takes approximately 8h 22m to drive from Louisville to Independence.
There are 243+ hotels available in Independence.














