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How to get fromLouisville to Appletonby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Amtrak, Flixbus)

Find Transport to Appleton

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There are 8 ways to get from Louisville to Appleton by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Appleton International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Appleton International Airport (ATW)plane plane SDF - ATW
    5h 39m
    $86–471

  2. Bus

    cheapest
    1. Take the bus from Louisville Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    2. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus FlixBus 2550
    11h 30m
    $74–118

  3. Bus, train

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Appletonbus bus
    13h 49m
    $103–238

  4. Drive  483.2 mi

    1. Drive from Louisville to Appletoncar car 483.2 mi
    8h 30m
    $89–128

  5. Drive to Blue Grass Airport, fly to Appleton International Airport

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Appleton International Airport (ATW)plane plane LEX - ATW
    5h 25m
    $87–397

  6. Fly Louisville International Airport to Green Bay

    1. Fly from Louisville International Airport (SDF) to Green Bay (GRB)plane plane SDF - GRB
    6h 58m
    $112–506

  7. Fly Louisville International Airport to General Mitchell International Airport, bus

    1. Fly from Louisville International Airport (SDF) to General Mitchell International Airport (MKE)plane plane SDF - MKE
    2. Take the bus from Milwaukee to Appletonbus bus
    8h 18m
    $108–629

  8. Bus via Lafayette

    1. Take the bus from Louisville, KY to Lafayette Amtrak Stationbus bus
    2. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    3. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus
    12h 39m
    $87–136

Louisville to Appleton by bus

Calendar5Weekly Buses
Duration11h 30mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Appleton.ExpandLaunch map view
  • Distance: 455.2 mi
  • Duration: 5h 39m

What companies run services between Louisville, KY, USA and Appleton, WI, USA?

United Airlines, Delta, and American Airlines fly from Louisville International Airport (SDF) to Appleton International Airport (ATW) hourly. Alternatively, you can take a bus from Louisville Bus Station to Appleton Transit Center via Chicago Bus Station in around 11h 30m.

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